CA2207627A1 - 4-(heterocycloalkyle ou heteroaromatique)-phenyle substituees-2-azetidinones utilisees en tant qu'agents hypolipidemiques - Google Patents
4-(heterocycloalkyle ou heteroaromatique)-phenyle substituees-2-azetidinones utilisees en tant qu'agents hypolipidemiquesInfo
- Publication number
- CA2207627A1 CA2207627A1 CA002207627A CA2207627A CA2207627A1 CA 2207627 A1 CA2207627 A1 CA 2207627A1 CA 002207627 A CA002207627 A CA 002207627A CA 2207627 A CA2207627 A CA 2207627A CA 2207627 A1 CA2207627 A1 CA 2207627A1
- Authority
- CA
- Canada
- Prior art keywords
- alkyl
- optionally substituted
- sum
- heterocycloalkyl
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000001072 heteroaryl group Chemical group 0.000 title abstract 4
- 125000000592 heterocycloalkyl group Chemical group 0.000 title abstract 4
- 125000001997 phenyl group Chemical class [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title abstract 2
- 239000003524 antilipemic agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 3
- 125000003107 substituted aryl group Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- MNFORVFSTILPAW-UHFFFAOYSA-N azetidin-2-one Chemical compound O=C1CCN1 MNFORVFSTILPAW-UHFFFAOYSA-N 0.000 abstract 2
- 125000003003 spiro group Chemical group 0.000 abstract 2
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 239000003529 anticholesteremic agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/361,265 US5656624A (en) | 1994-12-21 | 1994-12-21 | 4-[(heterocycloalkyl or heteroaromatic)-substituted phenyl]-2-azetidinones useful as hypolipidemic agents |
| US08/361,265 | 1994-12-21 | ||
| PCT/US1995/016007 WO1996019450A1 (fr) | 1994-12-21 | 1995-12-18 | 4-(heterocycloalkyle ou heteroaromatique)-phenyle substituees-2-azetidinones utilisees en tant qu'agents hypolipidemiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2207627A1 true CA2207627A1 (fr) | 1996-06-27 |
| CA2207627C CA2207627C (fr) | 2005-11-15 |
Family
ID=35530899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002207627A Expired - Fee Related CA2207627C (fr) | 1994-12-21 | 1995-12-18 | 4-(heterocycloalkyle ou heteroaromatique)-phenyle substituees-2-azetidinones utilisees en tant qu'agents hypolipidemiques |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2207627C (fr) |
-
1995
- 1995-12-18 CA CA002207627A patent/CA2207627C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2207627C (fr) | 2005-11-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20121218 |