CA2204864A1 - Procede de production de ceramique osseuse spongieuse a faible teneur en oxyde de calcium - Google Patents
Procede de production de ceramique osseuse spongieuse a faible teneur en oxyde de calciumInfo
- Publication number
- CA2204864A1 CA2204864A1 CA 2204864 CA2204864A CA2204864A1 CA 2204864 A1 CA2204864 A1 CA 2204864A1 CA 2204864 CA2204864 CA 2204864 CA 2204864 A CA2204864 A CA 2204864A CA 2204864 A1 CA2204864 A1 CA 2204864A1
- Authority
- CA
- Canada
- Prior art keywords
- bone
- calcium oxide
- ceramic
- production
- oxide content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 46
- 239000000919 ceramic Substances 0.000 title claims abstract description 29
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 title claims abstract description 23
- 239000000292 calcium oxide Substances 0.000 title claims abstract description 23
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 title claims abstract description 23
- 238000000034 method Methods 0.000 title claims abstract description 21
- 238000004519 manufacturing process Methods 0.000 title claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 210000002805 bone matrix Anatomy 0.000 claims abstract description 10
- 238000005406 washing Methods 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 abstract description 15
- 238000005245 sintering Methods 0.000 abstract description 7
- 230000033558 biomineral tissue development Effects 0.000 abstract description 5
- 229940087373 calcium oxide Drugs 0.000 description 18
- 235000012255 calcium oxide Nutrition 0.000 description 18
- 239000002253 acid Substances 0.000 description 6
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 5
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 5
- 238000002441 X-ray diffraction Methods 0.000 description 4
- 238000010306 acid treatment Methods 0.000 description 3
- 238000000197 pyrolysis Methods 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 239000007943 implant Substances 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 238000002386 leaching Methods 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000543381 Cliftonia monophylla Species 0.000 description 1
- 244000228957 Ferula foetida Species 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000316 bone substitute Substances 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 1
- 239000000920 calcium hydroxide Substances 0.000 description 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000008239 natural water Substances 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 230000000278 osteoconductive effect Effects 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000008237 rinsing water Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Landscapes
- Compositions Of Oxide Ceramics (AREA)
- Materials For Medical Uses (AREA)
Abstract
L'invention concerne un procédé de production de céramique osseuse spongieuse à faible teneur en oxyde de calcium. Entre la minéralisation du matériau osseux et la vitrification de la céramique, il est prévu une opération de lavage à l'aide d'eau déminéralisée, qui vise à éliminer la part d'oxyde de calcium contenue dans la matrice osseuse minéralisée.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4440149A DE4440149A1 (de) | 1994-11-10 | 1994-11-10 | Verfahren zur Herstellung von calciumoxidarmer Spongiosa-Knochenkeramik |
| DEP4440149.3 | 1994-11-10 | ||
| PCT/EP1995/004285 WO1996014886A1 (fr) | 1994-11-10 | 1995-11-02 | Procede de production de ceramique osseuse spongieuse a faible teneur en oxyde de calcium |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2204864A1 true CA2204864A1 (fr) | 1996-05-23 |
Family
ID=29403404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2204864 Abandoned CA2204864A1 (fr) | 1994-11-10 | 1995-11-02 | Procede de production de ceramique osseuse spongieuse a faible teneur en oxyde de calcium |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2204864A1 (fr) |
-
1995
- 1995-11-02 CA CA 2204864 patent/CA2204864A1/fr not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |