CA2203681A1 - Analogues d'amidines cycliques utilises comme inhibiteurs de la monoxyde d'azote synthetase - Google Patents

Analogues d'amidines cycliques utilises comme inhibiteurs de la monoxyde d'azote synthetase

Info

Publication number
CA2203681A1
CA2203681A1 CA 2203681 CA2203681A CA2203681A1 CA 2203681 A1 CA2203681 A1 CA 2203681A1 CA 2203681 CA2203681 CA 2203681 CA 2203681 A CA2203681 A CA 2203681A CA 2203681 A1 CA2203681 A1 CA 2203681A1
Authority
CA
Canada
Prior art keywords
imino
hydrochloride
methyl
hydrogen
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2203681
Other languages
English (en)
Inventor
Ravindra N. Guthikonda
Stephan K. Grant
Malcolm Maccoss
Shrenik K. Shah
Kothandaraman Shankaran
Charles G. Caldwell
Philippe L. Durette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/468,120 external-priority patent/US5629322A/en
Application filed by Individual filed Critical Individual
Publication of CA2203681A1 publication Critical patent/CA2203681A1/fr
Abandoned legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés hétérocycliques et des sels pharmaceutiquement acceptables de ceux-ci qui se sont montrés utilesdans le traitement des maladies et des troubles liés à la monoxyde d'azote synthétase.
CA 2203681 1994-11-15 1995-11-13 Analogues d'amidines cycliques utilises comme inhibiteurs de la monoxyde d'azote synthetase Abandoned CA2203681A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33960794A 1994-11-15 1994-11-15
US468,120 1995-06-06
US08/468,120 US5629322A (en) 1994-11-15 1995-06-06 Cyclic amidine analogs as inhibitors of nitric oxide synthase
US339,607 1995-06-06
PCT/US1995/014812 WO1996014844A1 (fr) 1994-11-15 1995-11-13 Analogues d'amidines cycliques utilises comme inhibiteurs de la monoxyde d'azote synthetase

Publications (1)

Publication Number Publication Date
CA2203681A1 true CA2203681A1 (fr) 1996-05-23

Family

ID=29407633

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2203681 Abandoned CA2203681A1 (fr) 1994-11-15 1995-11-13 Analogues d'amidines cycliques utilises comme inhibiteurs de la monoxyde d'azote synthetase

Country Status (1)

Country Link
CA (1) CA2203681A1 (fr)

Similar Documents

Publication Publication Date Title
AU702415B2 (en) Cyclic amidine analogs as inhibitors of nitric oxide synthase
JP7092784B2 (ja) αvβ6インテグリン阻害剤
KR100830902B1 (ko) 디펩티딜 펩티데이즈-iv(dpp-iv) 저해용 신규화합물, 그것의 제조방법 및 그것을 활성성분으로서함유하는 약제 조성물
TWI676628B (zh) 抑制mcl-1蛋白之化合物
CA2574301C (fr) Derives de la rifamycine (<i>r/s</i>), leur preparation et compositions pharmaceutiques
US20090312310A1 (en) Imidazothiazole derivatives
JP2010504967A (ja) 新規なβ−ラクタマーゼ阻害剤
EP2855469B1 (fr) 5-amino-[1,4]thiazines en tant qu'inhibiteurs de bace 1
CA1244016A (fr) Diazepinones condenses, procede de preparation et composes pharmaceutiques les contenant
CN117177744A (zh) Cdk2抑制剂及其使用方法
EP0372484A2 (fr) Benzènes condensés
CN102317289A (zh) 作为β分泌酶抑制剂的内酰胺
EP0520320A2 (fr) Dérivés de la tétrahydropyrrolo(1,2-a)pyrazine-4-spiro-3'-pyrrolidine, procédé pour leur préparation et compositions pharmaceutiques les contenant
AU2007331247B2 (en) 2-quinolinone and 2-quinoxalinone- derivatives and their use as antibacterial agents
KR900005014B1 (ko) 1,2,3,4-테트라히드로-6-치환-4-아릴(또는 헤테로시클로)-3-[(치환 아미노)카르보닐]-2-티옥소(또는 옥소)-5-피리미딘 카르복실산 및 에스테르 및 그의 제조 방법
AU2009324358A1 (en) Spiro azepane-oxazolidinones as Kv1.3 potassium channel blockers
CN108137608B (zh) Janus激酶1选择性抑制剂及其药物用途
US20110124867A1 (en) Process and intermediates for the Synthesis of heterocyclic Substituted Piperazines with CXCR3 Antagonist Activity
DE69619259T2 (de) Amidin- und isothioharnstoffderivate als inhibitoren der stickstoffoxid-synthase
EP3720855B1 (fr) Composés imidazopyridiniques et leur utilisation comme médicament
WO2024017880A1 (fr) Dérivés d'imidazotriazine utilisés comme modulateurs de l'il-17
KR20050096970A (ko) 트리시클릭 아제핀 유도체, 이의 제조 방법 및 이를포함하는 약학적 조성물
CA2203681A1 (fr) Analogues d'amidines cycliques utilises comme inhibiteurs de la monoxyde d'azote synthetase
HUT58318A (en) Process for producing pirimidinyl derivatives
CZ20013977A3 (cs) Substituované benzolaktamové sloučeniny

Legal Events

Date Code Title Description
FZDE Dead