CA2203273A1 - Synthese microbienne d'inhibiteurs de protease de hiv - Google Patents

Synthese microbienne d'inhibiteurs de protease de hiv

Info

Publication number
CA2203273A1
CA2203273A1 CA 2203273 CA2203273A CA2203273A1 CA 2203273 A1 CA2203273 A1 CA 2203273A1 CA 2203273 CA2203273 CA 2203273 CA 2203273 A CA2203273 A CA 2203273A CA 2203273 A1 CA2203273 A1 CA 2203273A1
Authority
CA
Canada
Prior art keywords
hiv
compound
aids
treatment
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2203273
Other languages
English (en)
Inventor
Byron H. Arison
Randall R. Miller
Ali Shafiee
Brian Heimbuch
George M. Garrity
Shieh-Shung T. Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/328,221 external-priority patent/US5612217A/en
Application filed by Individual filed Critical Individual
Publication of CA2203273A1 publication Critical patent/CA2203273A1/fr
Abandoned legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Des produits de biotransformation d'une fermentation avec une culture de MA7074 sont des inhibiteurs puissants de la protéase de HIV. Ces produits sont utiles dans la prévention ou le traitement de l'infection par HIV et dans le traitement du SIDA, sous forme de composés, de sels pharmaceutiquement acceptables, d'ingrédients de compositions pharmaceutiques, combinés ou non à d'autres agents antiviraux, immunomodulateurs, antibiotiques ou vaccins. L'invention concerne également des procédés de traitement du SIDA, ainsi que des procédés de prévention ou de traitement de l'infection par HIV.
CA 2203273 1994-10-25 1995-10-20 Synthese microbienne d'inhibiteurs de protease de hiv Abandoned CA2203273A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/328,221 US5612217A (en) 1994-10-25 1994-10-25 Streptomyces sp. MA 7074 (ATCC 55605) used for microbial synthesis of HIV protease inhibitors
US328,221 1994-10-25
PCT/US1995/013632 WO1996012790A1 (fr) 1994-10-25 1995-10-20 Synthese microbienne d'inhibiteurs de protease de hiv

Publications (1)

Publication Number Publication Date
CA2203273A1 true CA2203273A1 (fr) 1996-05-02

Family

ID=29405794

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2203273 Abandoned CA2203273A1 (fr) 1994-10-25 1995-10-20 Synthese microbienne d'inhibiteurs de protease de hiv

Country Status (1)

Country Link
CA (1) CA2203273A1 (fr)

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