CA2186621A1 - Compose antimicrobien contenant de la lanthionine - Google Patents

Compose antimicrobien contenant de la lanthionine

Info

Publication number
CA2186621A1
CA2186621A1 CA002186621A CA2186621A CA2186621A1 CA 2186621 A1 CA2186621 A1 CA 2186621A1 CA 002186621 A CA002186621 A CA 002186621A CA 2186621 A CA2186621 A CA 2186621A CA 2186621 A1 CA2186621 A1 CA 2186621A1
Authority
CA
Canada
Prior art keywords
peptide
pharmaceutically acceptable
peptide according
acid addition
acceptable acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002186621A
Other languages
English (en)
Inventor
Bruno Suri
John Edmondson Peel
Fritz Raschdorf
Josef Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9409200A external-priority patent/GB9409200D0/en
Priority claimed from GBGB9425886.0A external-priority patent/GB9425886D0/en
Application filed by Individual filed Critical Individual
Publication of CA2186621A1 publication Critical patent/CA2186621A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

On décrit un peptide antimicrobien contenant de la lanthionine, susceptible d'être obtenu à partir de la souche 664 de Staphylococcus hyicus, les sels d'addition d'acide de ce peptide, acceptables sur le plan pharmacologique, de même que des compositions pharmaceutiques comprenant ce peptide ou les sels d'addition d'acide de celui-ci ainsi que des molécules d'ADN codant ledit peptide. On purifie ce peptide à partir d'un milieu de culture de souche 664 de Staphylococcus hyicus, et on peut l'utiliser dans un procédé de traitement ou de prévention de la mastite chez un mammifère, qui consiste à administrer audit mammifère une quantité, efficace sur le plan pharmacologique, du composé ou d'un des sels d'addition d'acide de celui-ci, afin de traiter efficacement la mastite ou de supprimer de façon sûre le taux, la sévérité et la durée de l'infection bactérienne consécutive à celle-ci.
CA002186621A 1994-05-07 1995-04-26 Compose antimicrobien contenant de la lanthionine Abandoned CA2186621A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9409200A GB9409200D0 (en) 1994-05-07 1994-05-07 Antimicrobial compound
GB9409200.4 1994-12-21
GB9425886.0 1994-12-21
GBGB9425886.0A GB9425886D0 (en) 1994-12-21 1994-12-21 Antimicrobial compound

Publications (1)

Publication Number Publication Date
CA2186621A1 true CA2186621A1 (fr) 1995-11-16

Family

ID=26304850

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002186621A Abandoned CA2186621A1 (fr) 1994-05-07 1995-04-26 Compose antimicrobien contenant de la lanthionine

Country Status (5)

Country Link
EP (1) EP0759077A1 (fr)
JP (1) JPH09512711A (fr)
AU (1) AU2408695A (fr)
CA (1) CA2186621A1 (fr)
WO (1) WO1995030751A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070003508A1 (en) 2005-07-01 2007-01-04 Wooley Richard E Methods and compositions for promoting wound healing
NZ539076A (en) * 2005-03-29 2008-05-30 Blis Technologies Ltd Skin treatment compositions
US8383125B2 (en) 2006-03-23 2013-02-26 Agriculture Victoria Services Pty, Limited Antimicrobial protein
US20110209228A1 (en) * 2008-03-13 2011-08-25 Benjamin Cocks Method of treatment using antimicrobial composition

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0181578B1 (fr) * 1984-11-06 1991-09-04 Dr. Karl Thomae GmbH Polypeptide antibiotique, son procédé de préparation et son application
GB8811760D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Antibiotic

Also Published As

Publication number Publication date
EP0759077A1 (fr) 1997-02-26
AU2408695A (en) 1995-11-29
WO1995030751A1 (fr) 1995-11-16
JPH09512711A (ja) 1997-12-22

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Legal Events

Date Code Title Description
FZDE Dead