CA2182694C - Aerosols opthalmiques aqueux - Google Patents

Aerosols opthalmiques aqueux Download PDF

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Publication number
CA2182694C
CA2182694C CA002182694A CA2182694A CA2182694C CA 2182694 C CA2182694 C CA 2182694C CA 002182694 A CA002182694 A CA 002182694A CA 2182694 A CA2182694 A CA 2182694A CA 2182694 C CA2182694 C CA 2182694C
Authority
CA
Canada
Prior art keywords
formulation
spray nozzle
eye
droplets
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002182694A
Other languages
English (en)
Other versions
CA2182694A1 (fr
Inventor
Raymond Charles Rowe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca UK Ltd
Original Assignee
AstraZeneca UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9405952A external-priority patent/GB9405952D0/en
Application filed by AstraZeneca UK Ltd filed Critical AstraZeneca UK Ltd
Publication of CA2182694A1 publication Critical patent/CA2182694A1/fr
Application granted granted Critical
Publication of CA2182694C publication Critical patent/CA2182694C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B17/00—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups
    • B05B17/04—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods
    • B05B17/06—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations
    • B05B17/0607—Apparatus for spraying or atomising liquids or other fluent materials, not covered by the preceding groups operating with special methods using ultrasonic or other kinds of vibrations generated by electrical means, e.g. piezoelectric transducers

Landscapes

  • Medicinal Preparation (AREA)

Abstract

Un procédé permet d'administrer dans l'oeil une formulation ophtalmique liquide, qui comprend un liquide acceptable sur le plan ophtalmique et contient éventuellement une substance active sur ce même plan, caractérisée par une viscosité située entre 10?-3¿ et 1 Pa.s et une résistivité inférieure à 10?4¿ ohm.cm. Un jet de cette formulation est éjecté vers l'oeil par une buse de pulvérisation (12) adjacente à un transducteur (7) piézoélectrique ou électromagnétique, de façon à former un flux de gouttelettes non chargées, de taille uniforme et d'espacement égal. Ce flux de gouttelettes non chargées passe ensuite devant une électrode de charge (13) qui induit une charge électronique sur chaque gouttelette dudit flux, et les gouttelettes chargées déchargent cette charge électrique par mise à la terre en entrant en contact avec l'oeil. On décrit un pulvérisateur approprié à ce procédé.
CA002182694A 1994-03-25 1995-03-23 Aerosols opthalmiques aqueux Expired - Fee Related CA2182694C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9405952.4 1994-03-25
GB9405952A GB9405952D0 (en) 1994-03-25 1994-03-25 Aqueous ophthalmic sprays
PCT/GB1995/000643 WO1995026236A1 (fr) 1994-03-25 1995-03-23 Aerosols opthalmiques aqueux

Publications (2)

Publication Number Publication Date
CA2182694A1 CA2182694A1 (fr) 1995-10-05
CA2182694C true CA2182694C (fr) 2007-04-03

Family

ID=37951689

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002182694A Expired - Fee Related CA2182694C (fr) 1994-03-25 1995-03-23 Aerosols opthalmiques aqueux

Country Status (1)

Country Link
CA (1) CA2182694C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109674576B (zh) * 2017-10-19 2024-02-27 深圳市启明医药科技有限公司 流体供应单元及微液滴喷射驱动装置、发生装置

Also Published As

Publication number Publication date
CA2182694A1 (fr) 1995-10-05

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Effective date: 20130325