CA2179041C - Formulations de gelule a liberation biphasee - Google Patents

Formulations de gelule a liberation biphasee Download PDF

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Publication number
CA2179041C
CA2179041C CA002179041A CA2179041A CA2179041C CA 2179041 C CA2179041 C CA 2179041C CA 002179041 A CA002179041 A CA 002179041A CA 2179041 A CA2179041 A CA 2179041A CA 2179041 C CA2179041 C CA 2179041C
Authority
CA
Canada
Prior art keywords
formulation
fill
barrier
compositions
hydrophobic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002179041A
Other languages
English (en)
Other versions
CA2179041A1 (fr
Inventor
Stephen George Barnwell
Simon Higginbottom
Ian Peter Whelan
Stephen John Burns
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PII Drug Delivery LLC
Original Assignee
PII Drug Delivery LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939325445A external-priority patent/GB9325445D0/en
Application filed by PII Drug Delivery LLC filed Critical PII Drug Delivery LLC
Priority to CA2572498A priority Critical patent/CA2572498C/fr
Publication of CA2179041A1 publication Critical patent/CA2179041A1/fr
Application granted granted Critical
Publication of CA2179041C publication Critical patent/CA2179041C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Ces formulations de gélule comportent au moins deux compositions de remplissage différentes qu'on empêche de se mélanger soit en utilisant ces deux compositions sous forme solide, soit en prévoyant une barrière physique entre elles afin qu'elles ne puissent se mélanger. Cette invention présente l'avantage que l'on peut préparer ces deux différentes formulations dans une seule gélule sans qu'une formulation ait un effet adverse sur l'autre.
CA002179041A 1993-12-13 1994-12-12 Formulations de gelule a liberation biphasee Expired - Fee Related CA2179041C (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2572498A CA2572498C (fr) 1993-12-13 1994-12-12 Formulations de gelule a liberation biphasee

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939325445A GB9325445D0 (en) 1993-12-13 1993-12-13 Pharmaceutical formulations
GB9325445.6 1993-12-13
PCT/GB1994/002703 WO1995016438A1 (fr) 1993-12-13 1994-12-12 Formulations de gelule a liberation biphasee

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2572498A Division CA2572498C (fr) 1993-12-13 1994-12-12 Formulations de gelule a liberation biphasee

Publications (2)

Publication Number Publication Date
CA2179041A1 CA2179041A1 (fr) 1995-06-22
CA2179041C true CA2179041C (fr) 2007-04-10

Family

ID=38007157

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002179041A Expired - Fee Related CA2179041C (fr) 1993-12-13 1994-12-12 Formulations de gelule a liberation biphasee

Country Status (1)

Country Link
CA (1) CA2179041C (fr)

Also Published As

Publication number Publication date
CA2179041A1 (fr) 1995-06-22

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