CA2173957A1 - Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagas - Google Patents
Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagasInfo
- Publication number
- CA2173957A1 CA2173957A1 CA002173957A CA2173957A CA2173957A1 CA 2173957 A1 CA2173957 A1 CA 2173957A1 CA 002173957 A CA002173957 A CA 002173957A CA 2173957 A CA2173957 A CA 2173957A CA 2173957 A1 CA2173957 A1 CA 2173957A1
- Authority
- CA
- Canada
- Prior art keywords
- trypanosoma cruzi
- detection
- gene coding
- chagas
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6893—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for protozoa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne un nouvel antigène de Trypanosoma cruzi, dénommé PTc100, et un gène code codant pour ce demier, dénommé Tc100. Selon l'invention, on a déterminé et décrit les séquences nucléotidiques de Tc100 et d'acides aminés de PTc100. PTc100 et Tc100, ou leurs fragments, modifiés ou non, peuvent être utilisés directement ou indirectement pour la détection de Trypanosoma cruzi, ou le suivi de l'infection générée par ce dernier, chez l'homme ou l'animal.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR94/10132 | 1994-08-12 | ||
FR9410132A FR2723589B1 (fr) | 1994-08-12 | 1994-08-12 | Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagas |
PCT/FR1995/001071 WO1996005312A1 (fr) | 1994-08-12 | 1995-08-09 | Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagas |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2173957A1 true CA2173957A1 (fr) | 1996-02-22 |
CA2173957C CA2173957C (fr) | 2003-03-25 |
Family
ID=9466385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002173957A Expired - Fee Related CA2173957C (fr) | 1994-08-12 | 1995-08-09 | Nouvel antigene de trypanosoma cruzi, et gene codant pour cette derniere; leur application a la detection de la maladie de chagas |
Country Status (7)
Country | Link |
---|---|
US (3) | US5820864A (fr) |
EP (1) | EP0723589A1 (fr) |
AU (1) | AU3169195A (fr) |
BR (1) | BRPI9506314B8 (fr) |
CA (1) | CA2173957C (fr) |
FR (1) | FR2723589B1 (fr) |
WO (1) | WO1996005312A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6403103B1 (en) | 1994-08-12 | 2002-06-11 | Bio Merieux | Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease |
US7749717B2 (en) * | 2006-10-19 | 2010-07-06 | Abbott Laboratories | Methods for the detection and diagnosis of Trypanosoma cruzi infection |
WO2010129267A2 (fr) | 2009-04-27 | 2010-11-11 | University Of Georgia Research Foundation, Inc. | Peptides anti-trypanosome et leurs utilisations |
US20120316211A1 (en) * | 2011-05-11 | 2012-12-13 | The Board or Regents of the University of Texas System | Diagnostic Methods for Assessing Risk of Chagas Disease and Heart Failure |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4298596A (en) * | 1979-03-29 | 1981-11-03 | Burroughs Wellcome Co. | Trypanosoma cruzi glycoprotein vaccine for inducing immunity to Chagas' disease |
US5256545A (en) * | 1987-03-30 | 1993-10-26 | Board Of Regents, The University Of Texas System | Sterol Regulatory Elements |
US5495070A (en) * | 1988-10-04 | 1996-02-27 | Agracetus, Inc. | Genetically engineering cotton plants for altered fiber |
GB8904762D0 (en) * | 1989-03-02 | 1989-04-12 | Glaxo Group Ltd | Biological process |
WO1991017759A1 (fr) * | 1990-05-11 | 1991-11-28 | Research Corporation Technologies, Inc. | Facteur immunosuppresseur trypanosomique |
US5474925A (en) * | 1991-12-19 | 1995-12-12 | Agracetus, Inc. | Immobilized proteins in cotton fiber |
TW246717B (fr) * | 1992-07-10 | 1995-05-01 | Abbott Lab | |
US5312746A (en) * | 1993-01-08 | 1994-05-17 | Life Technologies, Inc. | Cloning and expressing restriction endonucleases and modification methylases from caryophanon |
-
1994
- 1994-08-12 FR FR9410132A patent/FR2723589B1/fr not_active Expired - Fee Related
-
1995
- 1995-06-07 US US08/480,917 patent/US5820864A/en not_active Expired - Lifetime
- 1995-08-09 AU AU31691/95A patent/AU3169195A/en not_active Abandoned
- 1995-08-09 WO PCT/FR1995/001071 patent/WO1996005312A1/fr not_active Application Discontinuation
- 1995-08-09 CA CA002173957A patent/CA2173957C/fr not_active Expired - Fee Related
- 1995-08-09 EP EP95927775A patent/EP0723589A1/fr not_active Withdrawn
- 1995-08-09 BR BRPI9506314A patent/BRPI9506314B8/pt not_active IP Right Cessation
-
1998
- 1998-08-24 US US09/138,736 patent/US6270767B1/en not_active Expired - Fee Related
- 1998-08-24 US US09/138,735 patent/US6933110B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
FR2723589B1 (fr) | 1996-09-20 |
US6933110B1 (en) | 2005-08-23 |
CA2173957C (fr) | 2003-03-25 |
US6270767B1 (en) | 2001-08-07 |
WO1996005312A1 (fr) | 1996-02-22 |
EP0723589A1 (fr) | 1996-07-31 |
BRPI9506314B8 (pt) | 2016-06-07 |
BR9506314A (pt) | 1997-08-05 |
MX9601346A (es) | 1998-06-30 |
US5820864A (en) | 1998-10-13 |
AU3169195A (en) | 1996-03-07 |
BR9506314B1 (pt) | 2010-08-10 |
FR2723589A1 (fr) | 1996-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |