CA2156075C - Aerosol formulation containing a dispersing aid - Google Patents

Aerosol formulation containing a dispersing aid Download PDF

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Publication number
CA2156075C
CA2156075C CA002156075A CA2156075A CA2156075C CA 2156075 C CA2156075 C CA 2156075C CA 002156075 A CA002156075 A CA 002156075A CA 2156075 A CA2156075 A CA 2156075A CA 2156075 C CA2156075 C CA 2156075C
Authority
CA
Canada
Prior art keywords
formulation according
group
formulation
chain
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002156075A
Other languages
English (en)
French (fr)
Other versions
CA2156075A1 (en
Inventor
Daniel C. Duan
James S. Stefely
David W. Schultz
Chester L. Leach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Publication of CA2156075A1 publication Critical patent/CA2156075A1/en
Application granted granted Critical
Publication of CA2156075C publication Critical patent/CA2156075C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002156075A 1993-03-17 1994-03-16 Aerosol formulation containing a dispersing aid Expired - Fee Related CA2156075C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3260593A 1993-03-17 1993-03-17
US08/032,605 1993-03-17
PCT/US1994/002826 WO1994021228A1 (en) 1993-03-17 1994-03-16 Aerosol formulation containing a diol-diacid derived dispersing aid

Publications (2)

Publication Number Publication Date
CA2156075A1 CA2156075A1 (en) 1994-09-29
CA2156075C true CA2156075C (en) 2004-06-22

Family

ID=21865817

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002156075A Expired - Fee Related CA2156075C (en) 1993-03-17 1994-03-16 Aerosol formulation containing a dispersing aid

Country Status (10)

Country Link
US (1) US6042811A (es)
EP (1) EP0689423B1 (es)
JP (1) JPH08507792A (es)
KR (1) KR100321650B1 (es)
AU (1) AU679510B2 (es)
CA (1) CA2156075C (es)
DE (1) DE69405719T2 (es)
ES (1) ES2107203T3 (es)
NZ (1) NZ263410A (es)
WO (1) WO1994021228A1 (es)

Families Citing this family (44)

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US6413536B1 (en) 1995-06-07 2002-07-02 Southern Biosystems, Inc. High viscosity liquid controlled delivery system and medical or surgical device
US7833543B2 (en) * 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
US6054488A (en) * 1996-06-11 2000-04-25 3M Innovative Properties Company Medicinal aerosol formulations of formoterol
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
AU2003204078B2 (en) * 1997-02-07 2006-08-17 Minnesota Mining And Manufacturing Company Biocompatible compounds for pharmaceutical drug delivery systems
AU761559B2 (en) * 1997-02-07 2003-06-05 Minnesota Mining And Manufacturing Company Biocompatible compounds for pharmaceutical drug delivery systems
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US20060025328A1 (en) * 1997-05-28 2006-02-02 Burns Patrick J Compositions suitable for controlled release of the hormone GnRH and its analogs
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US7087215B2 (en) * 1998-12-21 2006-08-08 Generex Pharmaceuticals Incorporated Methods of administering and enhancing absorption of pharmaceutical agents
US6849263B2 (en) * 1998-12-21 2005-02-01 Generex Pharmaceutical Incorporated Pharmaceutical compositions for buccal delivery of pain relief medications
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
AU5070100A (en) 2000-05-22 2001-12-03 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurised metered dose inhalers
PT1273292E (pt) 2001-07-02 2004-10-29 Chiesi Farma Spa Formulacao optimizada de tobramicina para aerossolizacao
US6592899B2 (en) 2001-10-03 2003-07-15 Macromed Incorporated PLA/PLGA oligomers combined with block copolymers for enhancing solubility of a drug in water
ATE406152T1 (de) * 2001-12-21 2008-09-15 3M Innovative Properties Co Medizinische aerosolzusammensetzungen mit einer eine amid- und/oder estergruppe enthaltenden exzipientenverbindung
JP2005514437A (ja) * 2001-12-21 2005-05-19 スリーエム イノベイティブ プロパティズ カンパニー イオン対複合体を含む医薬用エアロゾル製剤
WO2003059317A2 (en) * 2001-12-21 2003-07-24 3M Innovative Properties Company Medicinal aerosol compositions with a functionalized polyethyleneglycol excipient
GB0207906D0 (en) 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and mometasone aerosol formulations
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
PT2218448E (pt) 2002-12-13 2016-01-26 Durect Corp Sistema oral de entrega de fármaco que compreende materiais transportadores líquidos de alta viscosidade
US20060286138A1 (en) * 2003-04-10 2006-12-21 Malshe Vinod C Novel biodegradable aliphatic polyesters and pharmaceutical compositions and applications thereof
KR100998053B1 (ko) * 2004-01-29 2010-12-03 주식회사 엘지생활건강 화장비누 조성물
US20050287077A1 (en) * 2004-02-10 2005-12-29 James E. Shipley Process for preparing stable SOL of pharmaceutical ingredients and hydrofluorocarbon
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
SI2415484T1 (sl) 2004-09-17 2014-10-30 Durect Corporation Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem
US20070012186A1 (en) * 2005-03-11 2007-01-18 Wilson Todd S System and method of dehumidifying and filtering air
WO2007011763A2 (en) * 2005-07-15 2007-01-25 3M Innovative Properties Company Adhesive sheet and methods of use thereof
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
GB0614621D0 (en) 2006-07-24 2006-08-30 3M Innovative Properties Co Metered dose dispensers
GB0620700D0 (en) 2006-10-19 2006-11-29 3M Innovative Properties Co Metered dose valves and dispensers
PT2117521E (pt) 2006-11-03 2012-09-10 Durect Corp Sistemas de administração transdérmica que compreendem bupivacaína
EP3326621A1 (en) * 2007-12-06 2018-05-30 Durect Corporation Oral pharmaceutical dosage forms
GB0801876D0 (en) 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
GB201118188D0 (en) 2011-10-21 2011-12-07 3M Innovative Properties Co Manufacture of medicinal aerosol canisters
GB201210580D0 (en) 2012-06-14 2012-08-01 3M Innovative Properties Co Metered dose dispensing valve
GB201221063D0 (en) 2012-11-23 2013-01-09 3M Innovative Properties Co Metered dose dispensing valve
US9555113B2 (en) 2013-03-15 2017-01-31 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2733252A (en) * 1956-01-31 Salts of fatty acid esters of lactylic
US2362511A (en) * 1939-11-21 1944-11-14 Du Pont Modified glycolide resins
US2789992A (en) * 1951-12-12 1957-04-23 Patterson Co C Acyl lactylic acid products
US3098795A (en) * 1958-11-04 1963-07-23 Dyk & Company Inc Van Cosmetic compositions containing lactic acid esters of fatty alcohols
US3728447A (en) * 1970-03-03 1973-04-17 Patterson Co C Fatty acid lactylates and glycolates for conditioning hair
US3933825A (en) * 1973-05-14 1976-01-20 Bristol-Myers Company Amine salts of acyl lactylic acids
JPS5825720B2 (ja) * 1974-12-05 1983-05-28 ライオン株式会社 フンリユウジヨウセンジヨウザイソセイブツ
JPH0625090B2 (ja) * 1987-02-12 1994-04-06 花王株式会社 毛髪化粧料
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
US5008028A (en) * 1988-12-14 1991-04-16 The Lubrizol Corporation Liquid compositions containing carboxylic esters
GB8921222D0 (en) * 1989-09-20 1989-11-08 Riker Laboratories Inc Medicinal aerosol formulations
DE69109284T2 (de) * 1990-03-23 1995-08-24 Minnesota Mining And Mfg. Co., Saint Paul, Minn. Verwendung von fluorierten löslichen tensiden zur herstellung von aerosolarzneimitteln mit dosierter abgabe.
WO1992000062A1 (en) * 1990-06-27 1992-01-09 Minnesota Mining And Manufacturing Company The use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
US5126123A (en) * 1990-06-28 1992-06-30 Glaxo, Inc. Aerosol drug formulations
CA2085884C (en) * 1990-06-29 2001-12-04 Asit Somani Pressurized hydrofluorocarbon aerosol compositions
NZ244439A (en) * 1991-09-25 1994-01-26 Fisons Plc Pressurised aerosol compositions comprising hydrofluoroalkane, dispersed
US5658549A (en) * 1991-12-12 1997-08-19 Glaxo Group Limited Aerosol formulations containing propellant 134a and fluticasone propionate
US5266308A (en) * 1991-12-20 1993-11-30 Chesebrough-Pond's Usa Co. Hair treatment composition

Also Published As

Publication number Publication date
KR960700689A (ko) 1996-02-24
ES2107203T3 (es) 1997-11-16
WO1994021228A1 (en) 1994-09-29
DE69405719T2 (de) 1998-01-15
NZ263410A (en) 1997-05-26
US6042811A (en) 2000-03-28
CA2156075A1 (en) 1994-09-29
KR100321650B1 (ko) 2002-07-27
EP0689423A1 (en) 1996-01-03
JPH08507792A (ja) 1996-08-20
EP0689423B1 (en) 1997-09-17
AU679510B2 (en) 1997-07-03
AU6409394A (en) 1994-10-11
DE69405719D1 (de) 1997-10-23

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