CA2151473A1 - Synthese de polymeres encodes - Google Patents

Synthese de polymeres encodes

Info

Publication number
CA2151473A1
CA2151473A1 CA 2151473 CA2151473A CA2151473A1 CA 2151473 A1 CA2151473 A1 CA 2151473A1 CA 2151473 CA2151473 CA 2151473 CA 2151473 A CA2151473 A CA 2151473A CA 2151473 A1 CA2151473 A1 CA 2151473A1
Authority
CA
Canada
Prior art keywords
active
polymer
encoding
carbon atoms
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2151473
Other languages
English (en)
Inventor
Ronald N . Zuckermann
Janice M. Kerr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2151473A1 publication Critical patent/CA2151473A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00572—Chemical means
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Graft Or Block Polymers (AREA)
CA 2151473 1992-12-11 1993-12-10 Synthese de polymeres encodes Abandoned CA2151473A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98827892A 1992-12-11 1992-12-11
US07/988,278 1992-12-11

Publications (1)

Publication Number Publication Date
CA2151473A1 true CA2151473A1 (fr) 1994-06-23

Family

ID=25534002

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2151473 Abandoned CA2151473A1 (fr) 1992-12-11 1993-12-10 Synthese de polymeres encodes

Country Status (5)

Country Link
EP (1) EP0675873A4 (fr)
JP (1) JPH08504444A (fr)
AU (1) AU5827294A (fr)
CA (1) CA2151473A1 (fr)
WO (1) WO1994013623A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527675A (en) * 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
US5776737A (en) * 1994-12-22 1998-07-07 Visible Genetics Inc. Method and composition for internal identification of samples
GB9502225D0 (en) * 1995-02-04 1995-03-22 Zeneca Ltd Method
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
GB9515070D0 (en) * 1995-07-22 1995-09-20 Zeneca Ltd Label
EP2177627B1 (fr) * 1999-02-23 2012-05-02 Caliper Life Sciences, Inc. Manipulation de microparticules dans des systèmes microfluidiques
DE10041238A1 (de) * 2000-08-22 2002-03-07 Aventis Res & Tech Gmbh & Co Verfahren zur Identifizierung spezifisch spaltbarer peptide und Verwendung solcher Peptidsequenzen
WO2002052046A2 (fr) 2000-12-23 2002-07-04 Chiron Corporation Procede de criblage et de transfection d'oligonucleotides
US7727713B2 (en) 2001-06-20 2010-06-01 Nuevolution A/S Templated molecules and methods for using such molecules
NZ535144A (en) 2002-03-15 2006-03-31 Nuevolution As An improved method for synthesising templated molecules
AU2003247266A1 (en) 2002-08-01 2004-02-23 Nuevolution A/S Multi-step synthesis of templated molecules
HUE033651T2 (en) 2002-10-30 2017-12-28 Nuevolution As A method for producing two-function complexes
EP2175019A3 (fr) 2002-12-19 2011-04-06 Nuevolution A/S Procédés de synthèse guidée à fonction et structure quasi-sélectives
WO2004074429A2 (fr) 2003-02-21 2004-09-02 Nuevolution A/S Procede de production d'une banque de deuxieme generation
WO2004099441A2 (fr) * 2003-05-09 2004-11-18 Hyscite Discovery As Selection et developpement de bibliotheques chimiques
US11118215B2 (en) 2003-09-18 2021-09-14 Nuevolution A/S Method for obtaining structural information concerning an encoded molecule and method for selecting compounds
US7972994B2 (en) 2003-12-17 2011-07-05 Glaxosmithkline Llc Methods for synthesis of encoded libraries
JP5646127B2 (ja) * 2003-12-17 2014-12-24 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ コードされたライブラリーの合成のための方法
AU2006257915B2 (en) 2005-06-09 2011-09-08 Glaxosmithkline Llc Methods for synthesis of encoded libraries
AU2006309096B2 (en) * 2005-10-28 2013-07-04 Glaxosmithkline Llc Methods for identifying compounds of interest using encoded libraries
PT3305900T (pt) 2005-12-01 2021-10-27 Nuevolution As Métodos de codificação enzimática para síntese eficaz de bibliotecas grandes
EP3540059A1 (fr) 2010-04-16 2019-09-18 Nuevolution A/S Complexes bifonctionnels et procédés de fabrication et d'utilisation de tels complexes
LT3650459T (lt) * 2015-02-24 2023-12-27 City Of Hope Chemiškai koduotos erdviniu požiūriu orientuotos bibliotekos atrankos platformos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359353A (en) * 1981-05-18 1982-11-16 Hydrocarbon Research, Inc. Polypeptides as chemical tagging materials
WO1993006121A1 (fr) * 1991-09-18 1993-04-01 Affymax Technologies N.V. Procede de synthese de diverses collections d'oligomeres
CA2143848C (fr) * 1992-10-01 2007-09-11 W. Clark Still Chimie combinatoire complexe, avec encodage a l'aide de descripteurs

Also Published As

Publication number Publication date
WO1994013623A1 (fr) 1994-06-23
EP0675873A1 (fr) 1995-10-11
JPH08504444A (ja) 1996-05-14
AU5827294A (en) 1994-07-04
EP0675873A4 (fr) 2000-03-29

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead