CA2146856C - Methode et appareil pour le dosage de la glycemie sans effraction - Google Patents

Methode et appareil pour le dosage de la glycemie sans effraction Download PDF

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Publication number
CA2146856C
CA2146856C CA002146856A CA2146856A CA2146856C CA 2146856 C CA2146856 C CA 2146856C CA 002146856 A CA002146856 A CA 002146856A CA 2146856 A CA2146856 A CA 2146856A CA 2146856 C CA2146856 C CA 2146856C
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CA
Canada
Prior art keywords
wavelength
intensity
light
derivative
blood sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002146856A
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English (en)
Other versions
CA2146856A1 (fr
Inventor
Katsue Koashi
Shigeo Minami
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kurashiki Spinning Co Ltd
Original Assignee
Kurashiki Spinning Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kurashiki Spinning Co Ltd filed Critical Kurashiki Spinning Co Ltd
Priority to CA002146856A priority Critical patent/CA2146856C/fr
Priority to US08/411,631 priority patent/US5533509A/en
Priority to EP95908156A priority patent/EP0670143B1/fr
Priority to PCT/JP1993/001140 priority patent/WO1995005120A1/fr
Priority claimed from PCT/JP1993/001140 external-priority patent/WO1995005120A1/fr
Publication of CA2146856A1 publication Critical patent/CA2146856A1/fr
Application granted granted Critical
Publication of CA2146856C publication Critical patent/CA2146856C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7239Details of waveform analysis using differentiation including higher order derivatives
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/39Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/06Illumination; Optics
    • G01N2201/065Integrating spheres

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Artificial Intelligence (AREA)
  • Signal Processing (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Physiology (AREA)
  • Psychiatry (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Un faisceau laser, dont la longueur d'onde est modulée périodiquement, émis par un laser (11) à semi-conducteur à longueur d'onde variable est périodiquement modulé en intensité par un atténuateur (12). Ce faisceau laser est divisé par un diviseur de faisceau (14) de façon qu'il passe par deux chemins optiques (13a, 13b) et qu'il soit appliqué, par l'intermédiaire du chemin optique (13a) à une zone (17) dans laquelle le taux de sucre sanguin doit être mesuré. L'intensité de la lumière transmise à travers ladite zone (17) de l'objet ou bien de la lumière réfléchie par cette zone et l'intensité du faisceau laser dans le chemin optique (13b) sont détectées, respectivement, par un premier détecteur et un second détecteur, et le rapport d'une des intensités à l'autre intensité est déterminé par un amplificateur de rapport logarithmique (25). Un rapport de variation de ce rapport à une variation d'une longueur d'onde de modulation est détecté par un amplificateur synchrone (26), et un signal spectral différentiel du spectre d'absorption du glucose au niveau de la zone de l'objet est tiré de ce taux de variation. Une unité de traitement arithmétique (27) est conçue pour déterminer le taux de sucre sanguin de la zone de l'objet, sur la base de ce signal spectral différentiel.
CA002146856A 1993-08-12 1993-08-12 Methode et appareil pour le dosage de la glycemie sans effraction Expired - Fee Related CA2146856C (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002146856A CA2146856C (fr) 1993-08-12 1993-08-12 Methode et appareil pour le dosage de la glycemie sans effraction
US08/411,631 US5533509A (en) 1993-08-12 1993-08-12 Method and apparatus for non-invasive measurement of blood sugar level
EP95908156A EP0670143B1 (fr) 1993-08-12 1993-08-12 Procede non-invasif de mesure du taux de sucre sanguin et instrument de mesure utilise a cet effet
PCT/JP1993/001140 WO1995005120A1 (fr) 1993-08-12 1993-08-12 Procede non-invasif de mesure du taux de sucre sanguin et instrument de mesure utilise a cet effet

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002146856A CA2146856C (fr) 1993-08-12 1993-08-12 Methode et appareil pour le dosage de la glycemie sans effraction
PCT/JP1993/001140 WO1995005120A1 (fr) 1993-08-12 1993-08-12 Procede non-invasif de mesure du taux de sucre sanguin et instrument de mesure utilise a cet effet

Publications (2)

Publication Number Publication Date
CA2146856A1 CA2146856A1 (fr) 1995-02-23
CA2146856C true CA2146856C (fr) 2004-04-06

Family

ID=4155639

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002146856A Expired - Fee Related CA2146856C (fr) 1993-08-12 1993-08-12 Methode et appareil pour le dosage de la glycemie sans effraction

Country Status (1)

Country Link
CA (1) CA2146856C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020094233A1 (fr) * 2018-11-08 2020-05-14 Diamontech Ag Dispositif et procédé pour l'analyse d'une substance

Also Published As

Publication number Publication date
CA2146856A1 (fr) 1995-02-23

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