CA2146856C - Methode et appareil pour le dosage de la glycemie sans effraction - Google Patents
Methode et appareil pour le dosage de la glycemie sans effraction Download PDFInfo
- Publication number
- CA2146856C CA2146856C CA002146856A CA2146856A CA2146856C CA 2146856 C CA2146856 C CA 2146856C CA 002146856 A CA002146856 A CA 002146856A CA 2146856 A CA2146856 A CA 2146856A CA 2146856 C CA2146856 C CA 2146856C
- Authority
- CA
- Canada
- Prior art keywords
- wavelength
- intensity
- light
- derivative
- blood sugar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/39—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/06—Illumination; Optics
- G01N2201/065—Integrating spheres
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Biophysics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Artificial Intelligence (AREA)
- Signal Processing (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Physiology (AREA)
- Psychiatry (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Un faisceau laser, dont la longueur d'onde est modulée périodiquement, émis par un laser (11) à semi-conducteur à longueur d'onde variable est périodiquement modulé en intensité par un atténuateur (12). Ce faisceau laser est divisé par un diviseur de faisceau (14) de façon qu'il passe par deux chemins optiques (13a, 13b) et qu'il soit appliqué, par l'intermédiaire du chemin optique (13a) à une zone (17) dans laquelle le taux de sucre sanguin doit être mesuré. L'intensité de la lumière transmise à travers ladite zone (17) de l'objet ou bien de la lumière réfléchie par cette zone et l'intensité du faisceau laser dans le chemin optique (13b) sont détectées, respectivement, par un premier détecteur et un second détecteur, et le rapport d'une des intensités à l'autre intensité est déterminé par un amplificateur de rapport logarithmique (25). Un rapport de variation de ce rapport à une variation d'une longueur d'onde de modulation est détecté par un amplificateur synchrone (26), et un signal spectral différentiel du spectre d'absorption du glucose au niveau de la zone de l'objet est tiré de ce taux de variation. Une unité de traitement arithmétique (27) est conçue pour déterminer le taux de sucre sanguin de la zone de l'objet, sur la base de ce signal spectral différentiel.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002146856A CA2146856C (fr) | 1993-08-12 | 1993-08-12 | Methode et appareil pour le dosage de la glycemie sans effraction |
US08/411,631 US5533509A (en) | 1993-08-12 | 1993-08-12 | Method and apparatus for non-invasive measurement of blood sugar level |
EP95908156A EP0670143B1 (fr) | 1993-08-12 | 1993-08-12 | Procede non-invasif de mesure du taux de sucre sanguin et instrument de mesure utilise a cet effet |
PCT/JP1993/001140 WO1995005120A1 (fr) | 1993-08-12 | 1993-08-12 | Procede non-invasif de mesure du taux de sucre sanguin et instrument de mesure utilise a cet effet |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002146856A CA2146856C (fr) | 1993-08-12 | 1993-08-12 | Methode et appareil pour le dosage de la glycemie sans effraction |
PCT/JP1993/001140 WO1995005120A1 (fr) | 1993-08-12 | 1993-08-12 | Procede non-invasif de mesure du taux de sucre sanguin et instrument de mesure utilise a cet effet |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2146856A1 CA2146856A1 (fr) | 1995-02-23 |
CA2146856C true CA2146856C (fr) | 2004-04-06 |
Family
ID=4155639
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002146856A Expired - Fee Related CA2146856C (fr) | 1993-08-12 | 1993-08-12 | Methode et appareil pour le dosage de la glycemie sans effraction |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2146856C (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020094233A1 (fr) * | 2018-11-08 | 2020-05-14 | Diamontech Ag | Dispositif et procédé pour l'analyse d'une substance |
-
1993
- 1993-08-12 CA CA002146856A patent/CA2146856C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2146856A1 (fr) | 1995-02-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |