CA2140661A1 - Nouveaux composes chimioluminescents et methode d'utilisation - Google Patents
Nouveaux composes chimioluminescents et methode d'utilisationInfo
- Publication number
- CA2140661A1 CA2140661A1 CA002140661A CA2140661A CA2140661A1 CA 2140661 A1 CA2140661 A1 CA 2140661A1 CA 002140661 A CA002140661 A CA 002140661A CA 2140661 A CA2140661 A CA 2140661A CA 2140661 A1 CA2140661 A1 CA 2140661A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- analyte
- chemiluminescent
- group
- sbp member
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/805—Test papers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/818—Aeration or oxygen transfer technique
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91645392A | 1992-07-20 | 1992-07-20 | |
US07/916,453 | 1992-07-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2140661A1 true CA2140661A1 (fr) | 1994-02-03 |
Family
ID=25437285
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002140661A Abandoned CA2140661A1 (fr) | 1992-07-20 | 1993-07-19 | Nouveaux composes chimioluminescents et methode d'utilisation |
Country Status (5)
Country | Link |
---|---|
US (3) | US5545834A (fr) |
EP (1) | EP0651752A1 (fr) |
JP (1) | JPH07509245A (fr) |
CA (1) | CA2140661A1 (fr) |
WO (1) | WO1994002486A1 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109517802A (zh) * | 2018-11-20 | 2019-03-26 | 扬州大学 | 分泌鸡白痢沙门菌IpaJ单克隆抗体的杂交瘤细胞株、其单克隆抗体及其应用 |
CN113125714A (zh) * | 2019-12-31 | 2021-07-16 | 博阳生物科技(上海)有限公司 | 一种人类免疫缺陷病毒抗体检测试剂盒及其应用 |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6002000A (en) * | 1992-07-20 | 1999-12-14 | Dade Behring Marburg Gmbh | Chemiluminescent compounds and methods of use |
JPH07509245A (ja) * | 1992-07-20 | 1995-10-12 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 新規化学発光化合物およびその使用方法 |
US6159686A (en) | 1992-09-14 | 2000-12-12 | Sri International | Up-converting reporters for biological and other assays |
US5736410A (en) | 1992-09-14 | 1998-04-07 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
US6399397B1 (en) | 1992-09-14 | 2002-06-04 | Sri International | Up-converting reporters for biological and other assays using laser excitation techniques |
DE4442050A1 (de) * | 1994-11-25 | 1996-05-30 | Hoechst Ag | Heterospiroverbindungen und ihre Verwendung als Elektrolumineszenzmaterialien |
US5731148A (en) * | 1995-06-07 | 1998-03-24 | Gen-Probe Incorporated | Adduct protection assay |
US6087121A (en) * | 1997-07-11 | 2000-07-11 | Mayo Foundation For Medical Education And Research | Chemiluminescent detection of heme proteins in biological samples |
AU2679899A (en) * | 1998-02-18 | 1999-09-06 | Dade Behring Inc. | Chemiluminescent compositions for use in detection of multiple analytes |
US6838292B1 (en) | 1999-04-19 | 2005-01-04 | Alion Science And Technology Corporation | Detection of biological warfare agents |
WO2000079283A1 (fr) | 1999-06-23 | 2000-12-28 | Cornell Research Foundation, Inc. | Deshydration/rehydration de liposomes marques sur un dispositif d'essai |
AU6381900A (en) * | 1999-07-30 | 2001-02-19 | Bayer Corporation | Chemiluminescent substrates of hydrolytic enzymes such as phosphatases |
US6783948B1 (en) | 1999-07-30 | 2004-08-31 | Bayer Corporation | Chemiluminescent acridinium compounds and analogues thereof as substrates of hydrolytic enzymes |
US6576460B1 (en) | 1999-10-28 | 2003-06-10 | Cornell Research Foundation, Inc. | Filtration-detection device and method of use |
US6703248B1 (en) * | 1999-12-15 | 2004-03-09 | Dade Behring Marburg Gmbh | Particles for diagnostic and therapeutic use |
ATE395364T1 (de) | 1999-12-22 | 2008-05-15 | Dade Behring Marburg Gmbh | Gegen procalcitonin gerichtete antikörper, ihre herstellung und verwendung |
ES2280170T3 (es) * | 1999-12-22 | 2007-09-16 | Dade Behring Marburg Gmbh | Soluciones de procalcitonina humana. |
EP1264181B1 (fr) | 2000-03-06 | 2007-06-06 | Dade Behring Marburg GmbH | Supports a revetement en polysaccharides, leur preparation et leur utilisation |
US7635571B2 (en) * | 2000-12-07 | 2009-12-22 | Siemens Healthcare Diagnostics Products Gmbh | Amplified signal in binding assays |
DE10064827A1 (de) * | 2000-12-22 | 2002-06-27 | Dade Behring Marburg Gmbh | Nachweisverfahren |
US6872828B2 (en) | 2001-12-20 | 2005-03-29 | Lumigen, Inc. | Compounds for generating chemiluminescence with a peroxidase |
DE60237005D1 (de) * | 2001-02-28 | 2010-08-26 | Bio Merieux Inc | Integrierte filtrations- und detektionsvorrichtung |
US20030060695A1 (en) * | 2001-03-07 | 2003-03-27 | Connelly Patrick R. | Implantable artificial organ devices |
DE10111392A1 (de) | 2001-03-09 | 2002-09-12 | Chromeon Gmbh | Bioanalytisches Messverfahren unter Verwendung von Oxidasen |
US20050203578A1 (en) * | 2001-08-15 | 2005-09-15 | Weiner Michael L. | Process and apparatus for treating biological organisms |
DK1441737T3 (da) | 2001-10-30 | 2006-11-13 | Novartis Ag | Staurosporin-derivater som inhibitorer af FLT3-receptor-tyrosinkinase-aktivitet |
EP1512010B1 (fr) | 2002-05-31 | 2008-01-02 | Cornell Research Foundation, Inc. | Biocapteur universel et procedes d'utilisation |
US6897036B2 (en) * | 2002-06-06 | 2005-05-24 | Lumigen, Inc. | Fluorescent detection of peroxidase enzymes |
US7319041B2 (en) * | 2002-09-27 | 2008-01-15 | Siemens Medical Solutions Diagnostic | Applications of acridinium compounds and derivatives in homogeneous assays |
US7390670B2 (en) | 2003-02-20 | 2008-06-24 | Lumigen, Inc. | Signalling compounds and methods for detecting hydrogen peroxide |
GB0307403D0 (en) * | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
US7014925B2 (en) * | 2003-04-29 | 2006-03-21 | Canon Kabushiki Kaisha | Heterogeneous spiro compounds in organic light emitting device elements |
WO2005062048A1 (fr) | 2003-12-01 | 2005-07-07 | Dade Behring Marburg Gmbh | Procede de detection homogene |
US20050118727A1 (en) * | 2003-12-01 | 2005-06-02 | Carsten Schelp | Conjugates and their use in detection methods |
DE102005026163A1 (de) * | 2004-08-24 | 2006-03-02 | Dade Behring Marburg Gmbh | Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung |
US20060121491A1 (en) * | 2004-12-02 | 2006-06-08 | Wolber Paul K | Partially degenerate oligonucleotide standards and methods for generating the same |
EP2180323B1 (fr) * | 2005-04-06 | 2012-02-01 | Abbott Laboratories | Procédés permettant de mesurer les complexes immunosuppresseurs tacrolimus, sirolimus et cyclosporine A dans un prelèvement sanguin |
DE102005022047A1 (de) | 2005-05-09 | 2006-11-30 | Dade Behring Marburg Gmbh | Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung |
US9347947B2 (en) * | 2009-03-12 | 2016-05-24 | Siemens Healthcare Diagnostics Inc. | Immunoassays employing non-particulate chemiluminescent reagent |
US8153442B2 (en) * | 2009-10-21 | 2012-04-10 | Siemens Healthcare Diagnostics Inc. | Stabilization of signal generation in particles used in assays |
US20120318332A1 (en) * | 2011-06-19 | 2012-12-20 | John Cooper | System And Method For A Networked Solar Panel Railroad Infrastructure |
US9868030B2 (en) * | 2014-04-29 | 2018-01-16 | Clare Donovan | Chemiluminescent swim goggles |
US20210247398A1 (en) | 2018-07-30 | 2021-08-12 | Siemens Healthcare Diagnostics Inc. | Kits, microfluidics devices, and methods for performing biotin assays |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3876659A (en) * | 1970-09-18 | 1975-04-08 | Sandoz Ag | Spiro tricyclic isoindolines |
US4383031A (en) * | 1975-04-28 | 1983-05-10 | Miles Laboratories, Inc. | Homogeneous chemiluminescent specific binding assay |
US4380580A (en) * | 1978-04-10 | 1983-04-19 | Miles Laboratories, Inc. | Heterogenous chemiluminescent specific binding assay |
GB8420053D0 (en) * | 1984-08-07 | 1984-09-12 | Secr Social Service Brit | Enhanced luminescent/luminometric assay |
US4950588A (en) * | 1985-07-10 | 1990-08-21 | Molecular Diagnostics, Inc. | Prolonged enhanced chemiluminescence |
US5004565A (en) * | 1986-07-17 | 1991-04-02 | The Board Of Governors Of Wayne State University | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes |
US5616729A (en) * | 1986-07-17 | 1997-04-01 | Board Of Governors Of Wayne State University | Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers |
US4962192A (en) * | 1986-07-17 | 1990-10-09 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
US5013827A (en) * | 1986-07-17 | 1991-05-07 | Board Of Governors Of Wayne State University | Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers |
US4857652A (en) * | 1986-07-17 | 1989-08-15 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
US5068339A (en) * | 1986-07-17 | 1991-11-26 | Board Of Governors Of Wayne State University | Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers |
US4959182A (en) * | 1986-07-17 | 1990-09-25 | Board Of Governors Of Wayne State University | Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes |
US4931223A (en) * | 1986-07-24 | 1990-06-05 | Tropix, Inc. | Methods of using chemiluminescent 1,2-dioxetanes |
BR8707399A (pt) * | 1986-07-24 | 1988-09-13 | Quest Systems Inc | Metodo de detectar uma substancia usando decomposicao enzimaticamente induzida de dioxetanos |
US4810636A (en) * | 1986-12-09 | 1989-03-07 | Miles Inc. | Chromogenic acridinone enzyme substrates |
US4891324A (en) * | 1987-01-07 | 1990-01-02 | Syntex (U.S.A.) Inc. | Particle with luminescer for assays |
NL8703075A (nl) * | 1987-12-18 | 1989-07-17 | Nederlanden Staat | Acridiniumverbindingen als chemiluminescentie-merkstof. |
US5338847A (en) * | 1987-12-31 | 1994-08-16 | London Diagnostics, Inc. | Hydrolytically stable chemiluminescent labels and their conjugates, and assays therefrom by adduct formation |
NZ227506A (en) * | 1987-12-31 | 1992-06-25 | London Diagnostics Inc | Specific binding assays using chemiluminescent compounds |
US5281712A (en) * | 1987-12-31 | 1994-01-25 | London Diagnostics, Inc. | Ammonium substituted chemiluminescent labels and their conjugates, and assays therefrom |
US4950613A (en) * | 1988-02-26 | 1990-08-21 | Gen-Probe Incorporated | Proteted chemiluminescent labels |
WO1989012232A1 (fr) * | 1988-06-08 | 1989-12-14 | London Diagnostics, Inc. | Analyses mettant en oeuvre la production de signaux detectables induite par activateur |
US5055414A (en) * | 1988-07-05 | 1991-10-08 | Eastman Kodak Company | Phenalenimine fluorescent dyes and their use in analytical methods |
US5225584A (en) * | 1989-09-06 | 1993-07-06 | Tropix, Inc. | Synthesis of stable water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor |
JP3184894B2 (ja) * | 1989-10-05 | 2001-07-09 | エックスオックスエミス, インコーポレイテッド | ハロペルオキシターゼ酸至適化学的発光分析系 |
US5578498A (en) * | 1991-05-22 | 1996-11-26 | Behringwerke Ag | Metal chelate containing compositions for use in chemiluminescent assays |
US5154887A (en) * | 1991-05-28 | 1992-10-13 | Eastman Kodak Company | Phenalenimine fluorescent dyes and their use in analytical compositions, elements and methods |
JPH07509245A (ja) * | 1992-07-20 | 1995-10-12 | デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング | 新規化学発光化合物およびその使用方法 |
US5670644A (en) * | 1993-05-17 | 1997-09-23 | Lumigen, Inc. | Acridan compounds |
US5593845A (en) * | 1993-05-17 | 1997-01-14 | Lumigen, Inc. | Aryl N-alkylacridancarboxylate derivatives useful for chemiluminescent detection |
CA2170873A1 (fr) * | 1993-09-03 | 1995-03-09 | Dariush Davalian | Immuno-essais utilisant la fluorescence de l'oxygene |
-
1993
- 1993-07-19 JP JP6504547A patent/JPH07509245A/ja active Pending
- 1993-07-19 CA CA002140661A patent/CA2140661A1/fr not_active Abandoned
- 1993-07-19 EP EP93917182A patent/EP0651752A1/fr not_active Ceased
- 1993-07-19 WO PCT/US1993/006636 patent/WO1994002486A1/fr not_active Application Discontinuation
-
1995
- 1995-01-17 US US08/373,678 patent/US5545834A/en not_active Expired - Lifetime
-
1996
- 1996-06-11 US US08/664,269 patent/US5936070A/en not_active Expired - Lifetime
- 1996-06-11 US US08/661,846 patent/US5672478A/en not_active Expired - Lifetime
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109517802A (zh) * | 2018-11-20 | 2019-03-26 | 扬州大学 | 分泌鸡白痢沙门菌IpaJ单克隆抗体的杂交瘤细胞株、其单克隆抗体及其应用 |
CN109517802B (zh) * | 2018-11-20 | 2022-06-14 | 扬州大学 | 分泌鸡白痢沙门菌IpaJ单克隆抗体的杂交瘤细胞株、其单克隆抗体及其应用 |
CN113125714A (zh) * | 2019-12-31 | 2021-07-16 | 博阳生物科技(上海)有限公司 | 一种人类免疫缺陷病毒抗体检测试剂盒及其应用 |
CN113125714B (zh) * | 2019-12-31 | 2023-06-16 | 科美博阳诊断技术(上海)有限公司 | 一种人类免疫缺陷病毒抗体检测试剂盒及其应用 |
Also Published As
Publication number | Publication date |
---|---|
EP0651752A1 (fr) | 1995-05-10 |
US5936070A (en) | 1999-08-10 |
US5545834A (en) | 1996-08-13 |
US5672478A (en) | 1997-09-30 |
WO1994002486A1 (fr) | 1994-02-03 |
JPH07509245A (ja) | 1995-10-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |