CA2137779A1 - Purification de proteines renfermant du kringle, et particulierement le t-pa - Google Patents

Purification de proteines renfermant du kringle, et particulierement le t-pa

Info

Publication number
CA2137779A1
CA2137779A1 CA002137779A CA2137779A CA2137779A1 CA 2137779 A1 CA2137779 A1 CA 2137779A1 CA 002137779 A CA002137779 A CA 002137779A CA 2137779 A CA2137779 A CA 2137779A CA 2137779 A1 CA2137779 A1 CA 2137779A1
Authority
CA
Canada
Prior art keywords
plasminogen
acid
kringle
elution
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002137779A
Other languages
English (en)
Inventor
Marie Johannessen
Erik Halkjaer
Lars C. Petersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2137779A1 publication Critical patent/CA2137779A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002137779A 1992-06-23 1993-06-23 Purification de proteines renfermant du kringle, et particulierement le t-pa Abandoned CA2137779A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK92825A DK82592D0 (da) 1992-06-23 1992-06-23 Fremstilling af proteiner
DK0825/92 1992-06-23

Publications (1)

Publication Number Publication Date
CA2137779A1 true CA2137779A1 (fr) 1994-01-06

Family

ID=8097981

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002137779A Abandoned CA2137779A1 (fr) 1992-06-23 1993-06-23 Purification de proteines renfermant du kringle, et particulierement le t-pa

Country Status (11)

Country Link
EP (1) EP0672051A1 (fr)
JP (1) JPH07508009A (fr)
KR (1) KR950702204A (fr)
AU (1) AU4311893A (fr)
CA (1) CA2137779A1 (fr)
CZ (1) CZ328594A3 (fr)
DK (1) DK82592D0 (fr)
FI (1) FI946031A0 (fr)
HU (1) HUT71326A (fr)
NO (1) NO944981D0 (fr)
WO (1) WO1994000483A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6210906B1 (en) 1998-01-20 2001-04-03 Abbott Laboratories Specific antibodies to kringle 5 of apo(a) and methods of use therefor
EP1240200B1 (fr) * 1999-12-23 2009-06-03 Csl Limited Purification de fibrinogene present dans des proteases de plasma
AU8591901A (en) 2000-09-05 2002-03-22 Karolinska Innovations Ab Materials and methods relating to endothelial cell growth inhibitors
CZ20033097A3 (cs) * 2001-05-21 2004-06-16 Omrix Biopharmaceuticals S.A. Způsob odstranění plasmin(ogenu) z proteinových roztoků
CN110770340B (zh) * 2017-05-31 2023-09-19 Brain生物科技股份公司 在宿主细胞中丝氨酸蛋白酶的表达的优化

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6379591A (ja) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc ｔＰＡの精製方法

Also Published As

Publication number Publication date
CZ328594A3 (en) 1995-06-14
JPH07508009A (ja) 1995-09-07
EP0672051A1 (fr) 1995-09-20
FI946031A (fi) 1994-12-22
HUT71326A (en) 1995-11-28
WO1994000483A1 (fr) 1994-01-06
NO944981L (no) 1994-12-22
FI946031A0 (fi) 1994-12-22
DK82592D0 (da) 1992-06-23
KR950702204A (ko) 1995-06-19
AU4311893A (en) 1994-01-24
NO944981D0 (no) 1994-12-22

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Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 19970623