CA2121377C - Altered dipole moment magnetic resonance imaging method - Google Patents
Altered dipole moment magnetic resonance imaging method Download PDFInfo
- Publication number
- CA2121377C CA2121377C CA002121377A CA2121377A CA2121377C CA 2121377 C CA2121377 C CA 2121377C CA 002121377 A CA002121377 A CA 002121377A CA 2121377 A CA2121377 A CA 2121377A CA 2121377 C CA2121377 C CA 2121377C
- Authority
- CA
- Canada
- Prior art keywords
- stable
- xenon
- subject
- mole percent
- krypton
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Signal Processing (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/047,019 | 1993-04-16 | ||
| US08/047,019 US5357959A (en) | 1993-04-16 | 1993-04-16 | Altered dipole moment magnetic resonance imaging method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2121377A1 CA2121377A1 (en) | 1994-10-17 |
| CA2121377C true CA2121377C (en) | 2000-10-31 |
Family
ID=21946624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002121377A Expired - Fee Related CA2121377C (en) | 1993-04-16 | 1994-04-15 | Altered dipole moment magnetic resonance imaging method |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5357959A (OSRAM) |
| EP (1) | EP0620447B1 (OSRAM) |
| JP (1) | JP2807964B2 (OSRAM) |
| KR (1) | KR0177532B1 (OSRAM) |
| CN (1) | CN1093893A (OSRAM) |
| BR (1) | BR9401499A (OSRAM) |
| CA (1) | CA2121377C (OSRAM) |
| DE (1) | DE69427931T2 (OSRAM) |
| ES (1) | ES2158873T3 (OSRAM) |
| IL (1) | IL109281A (OSRAM) |
| TW (1) | TW281629B (OSRAM) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5494036A (en) | 1993-11-26 | 1996-02-27 | Medrad, Inc. | Patient infusion system for use with MRI |
| US5617861A (en) * | 1994-02-16 | 1997-04-08 | Huntington Medical Research Institutes | Magnetic resonance spectral analysis of the brain for diagnosis of clinical conditions |
| US5545396A (en) * | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
| US6123919A (en) * | 1994-04-08 | 2000-09-26 | The Trustees Of Princeton University | Magnetic resonance imaging using hyperpolarized noble gases |
| USH1968H1 (en) * | 1995-06-07 | 2001-06-05 | General Electric Company | Hyperpolarized MR imaging using pulse sequence with progressively increasing flip angle |
| US5617860A (en) * | 1995-06-07 | 1997-04-08 | Smithsonian Astrophysical Observatory | Method and system for producing polarized 129 Xe gas |
| US5617859A (en) * | 1995-10-02 | 1997-04-08 | General Electric Company | Apparatus and methods for magnetic resonance (MR) imaging of cavities using fluids polarized at low temperatures |
| US5611340A (en) * | 1995-10-02 | 1997-03-18 | General Electric Company | Apparatus and methods for magnetic resonance (MR) angiography using hydrogen polarized at low temperatures |
| WO1997037239A1 (en) | 1996-03-29 | 1997-10-09 | Lawrence Berkeley National Laboratory | Enhancement of nmr and mri in the presence of hyperpolarized noble gases |
| US8765099B2 (en) * | 1996-04-08 | 2014-07-01 | Koninklijke Philips N.V. | Magnetic resonance imaging hyperpolarization of liquids or solids by light with orbital angular momentum |
| IL119623A0 (en) * | 1996-11-15 | 1997-02-18 | Inta Medics Ltd | Non-invasive real time diagnosis of migraine |
| US6085743A (en) * | 1997-05-30 | 2000-07-11 | The Regent Of The University Of Michigan | Polarized gas delivery system/method |
| US6198957B1 (en) | 1997-12-19 | 2001-03-06 | Varian, Inc. | Radiotherapy machine including magnetic resonance imaging system |
| US6176838B1 (en) * | 1998-01-29 | 2001-01-23 | Anzai Medical Kabushiki Kaisha | Method and apparatus for measuring hepatic blood flow amount |
| US6321105B1 (en) * | 1998-04-08 | 2001-11-20 | Bracco S.P.A. | Method for diagnosing neurological, neurodegenerative and psychiatric diseases by magnetic resonance imaging using contrast agents with high magnetic susceptibility and extended plasma half life |
| EP1090250A1 (en) | 1998-06-17 | 2001-04-11 | Medi-Physics, Inc. | Hyperpolarized gas transport device and associated transport method |
| US6125654A (en) * | 1998-10-16 | 2000-10-03 | Syracuse University | Bulk production and usage of hyperpolarized 129 Xenon |
| US6284222B1 (en) | 1998-11-03 | 2001-09-04 | Medi--Physics, Inc. | Hyperpolarized helium-3 microbubble gas entrapment methods |
| GB9828853D0 (en) * | 1998-12-30 | 1999-02-17 | Nycomed Amersham Plc | Nmr spectroscopy method |
| US6295465B1 (en) * | 1999-02-17 | 2001-09-25 | Siemens Medical Systems, Inc. | Myocardial perfusion studies using magnetic resonance imaging |
| AU4686899A (en) | 1999-02-23 | 2000-09-14 | Medi-Physics, Inc. | Portable system for monitoring the polarization level of a hyperpolarized gas during transport |
| US6708053B1 (en) | 1999-03-04 | 2004-03-16 | Science And Technology Corp. @ Unm | Biochemical markers of brain function |
| DE19910986C2 (de) * | 1999-03-11 | 2001-06-07 | Aga Ab | Verwendung von Xenon bei der Behandlung von Neurointoxikationen |
| US6385479B1 (en) | 1999-03-31 | 2002-05-07 | Science & Technology Corporation @ Unm | Method for determining activity in the central nervous system |
| US6295834B1 (en) | 1999-06-30 | 2001-10-02 | Medi-Physics, Inc. | NMR polarization monitoring coils, hyperpolarizers with same, and methods for determining the polarization level of accumulated hyperpolarized noble gases during production |
| US6648130B1 (en) * | 1999-08-11 | 2003-11-18 | Medi-Physics, Inc. | Hyperpolarized gas transport and storage devices and associated transport and storage methods using permanent magnets |
| KR100577410B1 (ko) * | 1999-11-30 | 2006-05-08 | 엘지.필립스 엘시디 주식회사 | 엑스레이 영상 감지소자 및 그 제조방법 |
| US6704592B1 (en) | 2000-06-02 | 2004-03-09 | Medrad, Inc. | Communication systems for use with magnetic resonance imaging systems |
| US6652833B2 (en) | 2000-07-13 | 2003-11-25 | The Regents Of The University Of California | Functionalized active-nucleus complex sensor |
| US20030165431A1 (en) * | 2000-07-13 | 2003-09-04 | The Regents Of The University Of California | Method for detecting macromolecular conformational change and binding information |
| US7061237B2 (en) * | 2000-07-13 | 2006-06-13 | The Regents Of The University Of California | Remote NMR/MRI detection of laser polarized gases |
| AU2002220211A1 (en) * | 2000-12-07 | 2002-06-18 | Mclean Hospital Corporation | Use of magnetic resonance imaging in diagnosis of membrane fluidity-related disorders |
| JP2006524088A (ja) * | 2003-04-24 | 2006-10-26 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 繊維トラッキング磁気共鳴イメージング方法 |
| DE102005026604A1 (de) * | 2005-06-09 | 2006-12-14 | Membrana Gmbh | Verfahren zum Lösen von Gasen mit kurzlebigen physikalischen Eigenschaften in einer Flüssigkeit |
| US20090264733A1 (en) * | 2008-04-17 | 2009-10-22 | Regents Of The University Of Minnesota | Mri contrast using high transverse relaxation rate contrast agent |
| WO2010114609A1 (en) | 2009-04-02 | 2010-10-07 | Regents Of The University Of Minnesota | Localisation of magnetic particles by means of swift-mri |
| JP2012529960A (ja) * | 2009-06-19 | 2012-11-29 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 軌道角運動量を持つ光子を使用した過分極装置と組み合わせたｍｒｉ温度測定 |
| WO2016134275A1 (en) | 2015-02-20 | 2016-08-25 | Bayer Healthcare Llc | Contrast imaging agent with dissolved gas-evolving fluid |
| TWI611795B (zh) * | 2016-07-18 | 2018-01-21 | 許百靈 | 多針孔單光子ｓｐｅｃｔ心肌血流絕對定量方法與用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4586511A (en) * | 1983-03-04 | 1986-05-06 | Children's Hospital Medical Center | Methods and compositions for detecting and imaging a gas in an animal by nuclear magnetic resonance |
| JPS6347692A (ja) * | 1986-08-14 | 1988-02-29 | Toushina Seiki:Kk | 気圧変化警報装置 |
| US4893627A (en) * | 1988-05-26 | 1990-01-16 | The United States Of America As Represented By The United States Department Of Energy | Method for nuclear magnetic resonance imaging using deuterum as a contrast agent |
| US5186924A (en) * | 1991-01-16 | 1993-02-16 | Praxair Technology Inc. | Magnetic resonance human medical and veterinary imaging method |
| US5046498A (en) * | 1991-01-16 | 1991-09-10 | Union Carbide Industrial Gases Technology Corporation | Magnetic resonance human medical and veterinary imaging method |
| US5099834A (en) * | 1991-07-16 | 1992-03-31 | Union Carbide Industrial Gases Technology Corporation | Method for anesthesia |
-
1993
- 1993-04-16 US US08/047,019 patent/US5357959A/en not_active Expired - Fee Related
-
1994
- 1994-04-11 IL IL10928194A patent/IL109281A/en not_active IP Right Cessation
- 1994-04-15 CN CN94104432A patent/CN1093893A/zh active Pending
- 1994-04-15 KR KR1019940007927A patent/KR0177532B1/ko not_active Expired - Fee Related
- 1994-04-15 TW TW083103367A patent/TW281629B/zh active
- 1994-04-15 BR BR9401499A patent/BR9401499A/pt not_active Application Discontinuation
- 1994-04-15 DE DE69427931T patent/DE69427931T2/de not_active Expired - Fee Related
- 1994-04-15 EP EP94105891A patent/EP0620447B1/en not_active Expired - Lifetime
- 1994-04-15 JP JP6101481A patent/JP2807964B2/ja not_active Expired - Lifetime
- 1994-04-15 CA CA002121377A patent/CA2121377C/en not_active Expired - Fee Related
- 1994-04-15 ES ES94105891T patent/ES2158873T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69427931D1 (de) | 2001-09-20 |
| DE69427931T2 (de) | 2002-04-04 |
| EP0620447A3 (en) | 1995-06-14 |
| JP2807964B2 (ja) | 1998-10-08 |
| TW281629B (OSRAM) | 1996-07-21 |
| KR0177532B1 (ko) | 1999-04-01 |
| JPH06319721A (ja) | 1994-11-22 |
| IL109281A0 (en) | 1994-07-31 |
| ES2158873T3 (es) | 2001-09-16 |
| EP0620447B1 (en) | 2001-08-16 |
| CA2121377A1 (en) | 1994-10-17 |
| US5357959A (en) | 1994-10-25 |
| EP0620447A2 (en) | 1994-10-19 |
| IL109281A (en) | 1998-12-06 |
| KR940023441A (ko) | 1994-11-17 |
| BR9401499A (pt) | 1994-12-13 |
| CN1093893A (zh) | 1994-10-26 |
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