CA2110819A1 - Agents de visualisation specifiques d'un tissu, faisant appel a des anticorps anti-idiotypiques (image interne) - Google Patents

Agents de visualisation specifiques d'un tissu, faisant appel a des anticorps anti-idiotypiques (image interne)

Info

Publication number
CA2110819A1
CA2110819A1 CA002110819A CA2110819A CA2110819A1 CA 2110819 A1 CA2110819 A1 CA 2110819A1 CA 002110819 A CA002110819 A CA 002110819A CA 2110819 A CA2110819 A CA 2110819A CA 2110819 A1 CA2110819 A1 CA 2110819A1
Authority
CA
Canada
Prior art keywords
idiotypic antibody
recombinant
warm
fragmented
whole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002110819A
Other languages
English (en)
Inventor
Raghavan Rajagopalan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2110819A1 publication Critical patent/CA2110819A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1078Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being against an immunoglobulin, i.e. being an (anti)-anti-idiotypic antibody
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA002110819A 1991-07-01 1992-06-29 Agents de visualisation specifiques d'un tissu, faisant appel a des anticorps anti-idiotypiques (image interne) Abandoned CA2110819A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72422891A 1991-07-01 1991-07-01
US724,228 1991-07-01
PCT/US1992/005500 WO1993000934A1 (fr) 1991-07-01 1992-06-29 Agents d'imagerie specifiques aux tissus comprenant des anticorps anti-idiotypiques permettant de produire des images internes

Publications (1)

Publication Number Publication Date
CA2110819A1 true CA2110819A1 (fr) 1993-01-21

Family

ID=24909565

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002110819A Abandoned CA2110819A1 (fr) 1991-07-01 1992-06-29 Agents de visualisation specifiques d'un tissu, faisant appel a des anticorps anti-idiotypiques (image interne)

Country Status (5)

Country Link
EP (1) EP0592549A4 (fr)
JP (1) JPH06509102A (fr)
AU (1) AU2307092A (fr)
CA (1) CA2110819A1 (fr)
WO (1) WO1993000934A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030031627A1 (en) * 2001-07-31 2003-02-13 Mallinckrodt Inc. Internal image antibodies for optical imaging and therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4606855A (en) * 1982-07-26 1986-08-19 Mex Research Associates C/O Leon Reimer Monoclonal antibody to digoxin
US4859450A (en) * 1984-08-13 1989-08-22 The General Hospital Corporation Method of NMR imaging using antibody to cardiac myosin
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
US4735210A (en) * 1985-07-05 1988-04-05 Immunomedics, Inc. Lymphographic and organ imaging method and kit
US4732974A (en) * 1986-03-05 1988-03-22 Mallinckrodt, Inc. Metal ion labeling of carrier molecules
GB2189810B (en) * 1986-04-28 1990-10-10 Antibody Technology Ltd Antibodies their preparation and use and products containing them
US4861869A (en) * 1986-05-29 1989-08-29 Mallinckrodt, Inc. Coupling agents for joining radionuclide metal ions with biologically useful proteins
US4861581A (en) * 1986-12-05 1989-08-29 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
KR0162259B1 (ko) * 1989-12-05 1998-12-01 아미 펙터 감염성 병변 및 염증성 병변을 검출 및 치료하기 위한 키메라 항체

Also Published As

Publication number Publication date
EP0592549A1 (fr) 1994-04-20
JPH06509102A (ja) 1994-10-13
AU2307092A (en) 1993-02-11
WO1993000934A1 (fr) 1993-01-21
EP0592549A4 (fr) 2000-10-25

Similar Documents

Publication Publication Date Title
Goodwin et al. Pre-targeted immunoscintigraphy of murine tumors with indium-111-labeled bifunctional haptens
CA1260827A (fr) Complexes anticorps - ions metalliques
AU613318B2 (en) Affinity enhancement system
US5807879A (en) Biotinidase-resistant biotinylated compound and methods of use thereof
US4634586A (en) Reagent and method for radioimaging leukocytes
JP3051339B2 (ja) 治療的抗白血球結合体及び哺乳動物用非経口的注射剤
JP4169782B2 (ja) 低酸素症の検出
JPH03157338A (ja) ヒト腫瘍造影用注射組成物
Primus et al. Immunological considerations in the use of goat antibodies to carcinoembryonic antigen for the radioimmunodetection of cancer
CA1252714A (fr) Agent de diagnostic de cardiopathies et mode d'utilisation
Carney et al. Dual isotope study of iodine-125 and indium-111-labeled antibody in athymic mice
CA2113578A1 (fr) Composes trifonctionnels specifiques de cellules multiresistantes
US5084266A (en) Method for tumor imaging utilizing a labelled tumor specific antibody and a non-tumor reactive antibody
CA2110819A1 (fr) Agents de visualisation specifiques d'un tissu, faisant appel a des anticorps anti-idiotypiques (image interne)
JPH03198794A (ja) 抗ヒト心筋cプロテインモノクローナル抗体及び該抗体を産生するハイブリドーマ
US5208008A (en) Regioselective chemical modification of monoclonal antibodies
US4888163A (en) Diagnostic agent for breast cancer or tumor
EP0090025A1 (fr) Marquage specifique de glandes mammaires
EP0569531B1 (fr) Fragments d'anticorps stabilises
Gomibuchi et al. Radioimmunodetection of human melanoma tumor xenografts with human monoclonal antibodies
Cook The Development of Novel Platforms for the Imaging of Cancer by Positron Emission Tomography
Britton et al. Radioimmunoscintigraphy
Hailu Studies on the potential of radiolabeled MAb174H64 in the detection and radioimmunoscintigraphy of squamous cell carcinoma (SCC) and the preliminary characterization of the SCC associated antigen
Haptens Pre-TargetedImmunoscintigraphyof Murine
Schwarz et al. Radiolabeled Antibodies: Introduction and Metal Conjugation Techniques

Legal Events

Date Code Title Description
FZDE Discontinued
FZDE Discontinued

Effective date: 19960101