CA2106988C - Rotary disc filtration device - Google Patents
Rotary disc filtration deviceInfo
- Publication number
- CA2106988C CA2106988C CA002106988A CA2106988A CA2106988C CA 2106988 C CA2106988 C CA 2106988C CA 002106988 A CA002106988 A CA 002106988A CA 2106988 A CA2106988 A CA 2106988A CA 2106988 C CA2106988 C CA 2106988C
- Authority
- CA
- Canada
- Prior art keywords
- filter
- fluid
- disc
- gap
- filtration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000001914 filtration Methods 0.000 title claims abstract description 217
- 239000012530 fluid Substances 0.000 claims abstract description 230
- 239000012466 permeate Substances 0.000 claims abstract description 103
- 238000004891 communication Methods 0.000 claims abstract description 14
- 238000000034 method Methods 0.000 claims description 38
- 239000012465 retentate Substances 0.000 claims description 37
- 230000008569 process Effects 0.000 claims description 33
- 239000000126 substance Substances 0.000 claims description 20
- 239000000463 material Substances 0.000 claims description 18
- 239000002245 particle Substances 0.000 claims description 16
- 239000003446 ligand Substances 0.000 claims description 15
- 239000013060 biological fluid Substances 0.000 claims description 12
- 239000003921 oil Substances 0.000 claims description 12
- 238000001179 sorption measurement Methods 0.000 claims description 12
- 238000012360 testing method Methods 0.000 claims description 12
- 241000894007 species Species 0.000 claims description 11
- 239000011159 matrix material Substances 0.000 claims description 10
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- 238000000855 fermentation Methods 0.000 claims description 4
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- 244000005700 microbiome Species 0.000 claims description 3
- 239000002243 precursor Substances 0.000 claims description 3
- 239000007790 solid phase Substances 0.000 claims description 3
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 2
- 239000002250 absorbent Substances 0.000 claims description 2
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- 238000009295 crossflow filtration Methods 0.000 description 8
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
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- 108091003079 Bovine Serum Albumin Proteins 0.000 description 3
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- 229940098773 bovine serum albumin Drugs 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000001471 micro-filtration Methods 0.000 description 3
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- 230000036961 partial effect Effects 0.000 description 3
- 238000007873 sieving Methods 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000006227 byproduct Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000009920 chelation Effects 0.000 description 2
- 239000012527 feed solution Substances 0.000 description 2
- 108010074605 gamma-Globulins Proteins 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000000873 masking effect Effects 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 239000008267 milk Substances 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 235000015205 orange juice Nutrition 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 239000000376 reactant Substances 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 235000019499 Citrus oil Nutrition 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000001261 affinity purification Methods 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 150000001335 aliphatic alkanes Chemical class 0.000 description 1
- 150000001336 alkenes Chemical class 0.000 description 1
- 150000001345 alkine derivatives Chemical class 0.000 description 1
- 235000015197 apple juice Nutrition 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 229960000074 biopharmaceutical Drugs 0.000 description 1
- 235000010633 broth Nutrition 0.000 description 1
- 235000014171 carbonated beverage Nutrition 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- NCEXYHBECQHGNR-UHFFFAOYSA-N chembl421 Chemical compound C1=C(O)C(C(=O)O)=CC(N=NC=2C=CC(=CC=2)S(=O)(=O)NC=2N=CC=CC=2)=C1 NCEXYHBECQHGNR-UHFFFAOYSA-N 0.000 description 1
- 238000007385 chemical modification Methods 0.000 description 1
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- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000010500 citrus oil Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
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- 238000005859 coupling reaction Methods 0.000 description 1
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- 238000007872 degassing Methods 0.000 description 1
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- 238000000909 electrodialysis Methods 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 229920006334 epoxy coating Polymers 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000012065 filter cake Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000007792 gaseous phase Substances 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 210000004408 hybridoma Anatomy 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 229910001410 inorganic ion Inorganic materials 0.000 description 1
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- 239000000543 intermediate Substances 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000003350 kerosene Substances 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 238000010327 methods by industry Methods 0.000 description 1
- FYFFGSSZFBZTAH-UHFFFAOYSA-N methylaminomethanetriol Chemical compound CNC(O)(O)O FYFFGSSZFBZTAH-UHFFFAOYSA-N 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000004745 nonwoven fabric Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 238000005373 pervaporation Methods 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000010287 polarization Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 239000012429 reaction media Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 238000004064 recycling Methods 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
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- 239000011347 resin Substances 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
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- 235000000346 sugar Nutrition 0.000 description 1
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- 239000000725 suspension Substances 0.000 description 1
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- 239000002562 thickening agent Substances 0.000 description 1
- 238000013519 translation Methods 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- -1 vaccines Substances 0.000 description 1
- 238000011514 vinification Methods 0.000 description 1
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- 239000002699 waste material Substances 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/08—Prevention of membrane fouling or of concentration polarisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/01—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements
- B01D29/05—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements supported
- B01D29/055—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with flat filtering elements supported ring shaped
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/39—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with hollow discs side by side on, or around, one or more tubes, e.g. of the leaf type
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/50—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition
- B01D29/52—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition in parallel connection
- B01D29/54—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition in parallel connection arranged concentrically or coaxially
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/76—Handling the filter cake in the filter for purposes other than for regenerating
- B01D29/86—Retarding cake deposition on the filter during the filtration period, e.g. using stirrers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/88—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor having feed or discharge devices
- B01D29/94—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor having feed or discharge devices for discharging the filter cake, e.g. chutes
- B01D29/945—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor having feed or discharge devices for discharging the filter cake, e.g. chutes for continuously discharging concentrated liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D29/00—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor
- B01D29/96—Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups B01D24/00 - B01D27/00; Filtering elements therefor in which the filtering elements are moved between filtering operations; Particular measures for removing or replacing the filtering elements; Transport systems for filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/15—Filters with filtering elements which move during the filtering operation with rotary plane filtering surfaces
- B01D33/21—Filters with filtering elements which move during the filtering operation with rotary plane filtering surfaces with hollow filtering discs transversely mounted on a hollow rotary shaft
- B01D33/23—Construction of discs or component sectors thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/35—Filters with filtering elements which move during the filtering operation with multiple filtering elements characterised by their mutual disposition
- B01D33/37—Filters with filtering elements which move during the filtering operation with multiple filtering elements characterised by their mutual disposition in parallel connection
- B01D33/39—Filters with filtering elements which move during the filtering operation with multiple filtering elements characterised by their mutual disposition in parallel connection concentrically or coaxially
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/70—Filters with filtering elements which move during the filtering operation having feed or discharge devices
- B01D33/72—Filters with filtering elements which move during the filtering operation having feed or discharge devices for feeding
- B01D33/722—Filters with filtering elements which move during the filtering operation having feed or discharge devices for feeding containing fixed liquid displacement elements or cores
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/70—Filters with filtering elements which move during the filtering operation having feed or discharge devices
- B01D33/76—Filters with filtering elements which move during the filtering operation having feed or discharge devices for discharging the filter cake, e.g. chutes
- B01D33/763—Filters with filtering elements which move during the filtering operation having feed or discharge devices for discharging the filter cake, e.g. chutes for continuously discharging concentrated liquid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/80—Accessories
- B01D33/803—Accessories in which the filtering elements are moved between filtering operations ; Particular measures for removing or replacing the filtering elements; Transport systems for filters
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/06—Filters making use of electricity or magnetism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/16—Rotary, reciprocated or vibrated modules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/20—By influencing the flow
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/20—By influencing the flow
- B01D2321/2033—By influencing the flow dynamically
- B01D2321/2058—By influencing the flow dynamically by vibration of the membrane, e.g. with an actuator
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Filtering Of Dispersed Particles In Gases (AREA)
- Centrifugal Separators (AREA)
- Filtering Materials (AREA)
- Filtration Of Liquid (AREA)
- Fluid-Pressure Circuits (AREA)
- Control Of Throttle Valves Provided In The Intake System Or In The Exhaust System (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US708,069 | 1991-05-30 | ||
| US07/708,069 US5143630A (en) | 1991-05-30 | 1991-05-30 | Rotary disc filtration device |
| PCT/US1992/004634 WO1992021426A1 (en) | 1991-05-30 | 1992-05-28 | Rotary disc filtration device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2106988A1 CA2106988A1 (en) | 1992-12-01 |
| CA2106988C true CA2106988C (en) | 1999-06-22 |
Family
ID=24844268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002106988A Expired - Lifetime CA2106988C (en) | 1991-05-30 | 1992-05-28 | Rotary disc filtration device |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5143630A (en:Method) |
| EP (1) | EP0586591B1 (en:Method) |
| JP (1) | JPH0771603B2 (en:Method) |
| AT (1) | ATE182806T1 (en:Method) |
| AU (1) | AU650159B2 (en:Method) |
| CA (1) | CA2106988C (en:Method) |
| DE (1) | DE69229730T2 (en:Method) |
| WO (1) | WO1992021426A1 (en:Method) |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993012859A1 (en) * | 1991-12-24 | 1993-07-08 | Pall Corporation | Dynamic filter system |
| GB2302822B (en) * | 1991-12-24 | 1997-04-02 | Pall Corp | Dynamic filter system |
| US5679249A (en) * | 1991-12-24 | 1997-10-21 | Pall Corporation | Dynamic filter system |
| DE4207614C1 (en:Method) * | 1992-03-10 | 1993-09-23 | Pall Corp., Glen Cove, N.Y., Us | |
| US5578213A (en) * | 1992-07-28 | 1996-11-26 | Pall Corporation | Fluid treatment process |
| US5374356A (en) * | 1992-07-28 | 1994-12-20 | Pall Corporation | Fluid treatment process using dynamic microfiltration and ultrafiltration |
| WO1994003266A1 (en) * | 1992-08-03 | 1994-02-17 | Maloney James V Jr | Improved mass and thermal transfer means for use in heart lung machines, dialyzers, and other applications |
| US5395531A (en) * | 1992-09-28 | 1995-03-07 | Pall Corporation | Method for fractionating a fat composition |
| US6117322A (en) * | 1993-06-23 | 2000-09-12 | Pall Corporation | Dynamic filter system |
| CA2127605A1 (en) * | 1993-12-23 | 1995-06-24 | Peter J. Degen | Affinity separation method |
| US5798041A (en) * | 1995-09-06 | 1998-08-25 | Hemasure, Inc. | In-line liquid filtration device useable for blood, blood products or the like |
| US6251292B1 (en) | 1994-03-10 | 2001-06-26 | Hemasure, Inc. | Method of preventing air from becoming entrapped within a filtration device |
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-
1991
- 1991-05-30 US US07/708,069 patent/US5143630A/en not_active Expired - Lifetime
-
1992
- 1992-05-28 AU AU21719/92A patent/AU650159B2/en not_active Expired
- 1992-05-28 CA CA002106988A patent/CA2106988C/en not_active Expired - Lifetime
- 1992-05-28 EP EP92913641A patent/EP0586591B1/en not_active Expired - Lifetime
- 1992-05-28 DE DE69229730T patent/DE69229730T2/de not_active Expired - Fee Related
- 1992-05-28 JP JP5500625A patent/JPH0771603B2/ja not_active Expired - Fee Related
- 1992-05-28 WO PCT/US1992/004634 patent/WO1992021426A1/en not_active Ceased
- 1992-05-28 AT AT92913641T patent/ATE182806T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH06503033A (ja) | 1994-04-07 |
| AU650159B2 (en) | 1994-06-09 |
| ATE182806T1 (de) | 1999-08-15 |
| JPH0771603B2 (ja) | 1995-08-02 |
| EP0586591A4 (en:Method) | 1994-04-27 |
| EP0586591B1 (en) | 1999-08-04 |
| CA2106988A1 (en) | 1992-12-01 |
| EP0586591A1 (en) | 1994-03-16 |
| US5143630A (en) | 1992-09-01 |
| DE69229730T2 (de) | 1999-12-02 |
| DE69229730D1 (de) | 1999-09-09 |
| WO1992021426A1 (en) | 1992-12-10 |
| AU2171992A (en) | 1993-01-08 |
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