CA2106191A1 - System for high-speed measurement and sorting of particles - Google Patents
System for high-speed measurement and sorting of particlesInfo
- Publication number
- CA2106191A1 CA2106191A1 CA002106191A CA2106191A CA2106191A1 CA 2106191 A1 CA2106191 A1 CA 2106191A1 CA 002106191 A CA002106191 A CA 002106191A CA 2106191 A CA2106191 A CA 2106191A CA 2106191 A1 CA2106191 A1 CA 2106191A1
- Authority
- CA
- Canada
- Prior art keywords
- logic
- detection signals
- signal
- particle
- signals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
- B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
- B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
- B07C5/34—Sorting according to other particular properties
- B07C5/342—Sorting according to other particular properties according to optical properties, e.g. colour
- B07C5/3425—Sorting according to other particular properties according to optical properties, e.g. colour of granular material, e.g. ore particles, grain
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S209/00—Classifying, separating, and assorting solids
- Y10S209/906—Pneumatic or liquid stream feeding item
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Developing Agents For Electrophotography (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US671,009 | 1991-03-18 | ||
| US07/671,009 US5204884A (en) | 1991-03-18 | 1991-03-18 | System for high-speed measurement and sorting of particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2106191A1 true CA2106191A1 (en) | 1992-09-19 |
Family
ID=24692785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002106191A Abandoned CA2106191A1 (en) | 1991-03-18 | 1992-03-18 | System for high-speed measurement and sorting of particles |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5204884A (enExample) |
| EP (2) | EP0576583B1 (enExample) |
| JP (1) | JPH06507241A (enExample) |
| AT (1) | ATE184993T1 (enExample) |
| CA (1) | CA2106191A1 (enExample) |
| DE (1) | DE69230033T2 (enExample) |
| WO (1) | WO1992016829A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7043500B2 (en) | 2001-04-25 | 2006-05-09 | Board Of Regents, The University Of Texas Syxtem | Subtractive clustering for use in analysis of data |
Families Citing this family (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5199576A (en) * | 1991-04-05 | 1993-04-06 | University Of Rochester | System for flexibly sorting particles |
| US6136540A (en) * | 1994-10-03 | 2000-10-24 | Ikonisys Inc. | Automated fluorescence in situ hybridization detection of genetic abnormalities |
| US5352613A (en) * | 1993-10-07 | 1994-10-04 | Tafas Triantafillos P | Cytological screening method |
| DE69532045T2 (de) * | 1994-08-01 | 2004-07-08 | Abbott Laboratories, Abbott Park | Verfahren und Vorrichtung zur Vorbereitung einer Flüssigkeit |
| US5891734A (en) * | 1994-08-01 | 1999-04-06 | Abbott Laboratories | Method for performing automated analysis |
| US5656499A (en) * | 1994-08-01 | 1997-08-12 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
| US5631165A (en) * | 1994-08-01 | 1997-05-20 | Abbott Laboratories | Method for performing automated hematology and cytometry analysis |
| DE19520298A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Sortiervorrichtung für biologische Zellen oder Viren |
| US5736330A (en) * | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
| EP0852004B1 (en) | 1995-10-11 | 2011-01-19 | Luminex Corporation | Multiplexed analysis of clinical specimens |
| US5981180A (en) * | 1995-10-11 | 1999-11-09 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
| US5837547A (en) * | 1995-12-27 | 1998-11-17 | Caribbean Microparticles Corporation | Flow cytometer calibration method |
| US6449562B1 (en) | 1996-10-10 | 2002-09-10 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and method |
| EP2264427B1 (en) | 1997-01-31 | 2017-05-03 | Xy, Llc | Optical apparatus with focussing reflector for converging radiation onto a flow of particles, and related method of analysis |
| US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US6281018B1 (en) * | 1998-02-26 | 2001-08-28 | Coulter International Corp. | Selective purification and enrichment sorting of flow cytometer droplets based upon analysis of droplet precursor regions |
| US7024316B1 (en) * | 1999-10-21 | 2006-04-04 | Dakocytomation Colorado, Inc. | Transiently dynamic flow cytometer analysis system |
| JP2003512605A (ja) * | 1999-10-21 | 2003-04-02 | サイトメーション, インコーポレイテッド | 一時的動的フローサイトメータ分析システム |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| AU3768902A (en) | 2000-11-29 | 2002-06-11 | Xy Inc | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| US6793642B2 (en) * | 2001-05-07 | 2004-09-21 | Biomed Solutions, Llc | Flow cytometer |
| EP1405058A4 (en) * | 2001-03-19 | 2007-07-04 | Ikonisys Inc | SYSTEM AND METHOD FOR INCREASING THE CONTRAST OF AN IMAGE PRODUCED BY AN EPIFLUORESCENT MICROSCOPE |
| US20030040119A1 (en) * | 2001-04-11 | 2003-02-27 | The Regents Of The University Of Michigan | Separation devices and methods for separating particles |
| AU2003202943A1 (en) * | 2002-01-10 | 2003-07-30 | Board Of Regents, The University Of Texas System | Flow sorting system and methods regarding same |
| US20030175980A1 (en) * | 2002-03-14 | 2003-09-18 | Hayenga Jon W. | Ribbon flow cytometry and cell sorting |
| US6976590B2 (en) | 2002-06-24 | 2005-12-20 | Cytonome, Inc. | Method and apparatus for sorting particles |
| US9943847B2 (en) | 2002-04-17 | 2018-04-17 | Cytonome/St, Llc | Microfluidic system including a bubble valve for regulating fluid flow through a microchannel |
| US6808075B2 (en) | 2002-04-17 | 2004-10-26 | Cytonome, Inc. | Method and apparatus for sorting particles |
| JP2005533501A (ja) * | 2002-07-22 | 2005-11-10 | エックスワイ,インコーポレイテッド | 精子細胞操作系 |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| NZ538462A (en) | 2002-08-01 | 2008-06-30 | Xy Inc | Low pressure sperm cell separation system |
| BRPI0313476B1 (pt) | 2002-08-15 | 2015-06-23 | Xy Llc | Citômetro de fluxo de alta resolução |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| WO2004025266A2 (en) * | 2002-09-16 | 2004-03-25 | Cytonome, Inc | Method and apparatus for sorting particles |
| EP2194379B1 (en) | 2003-03-28 | 2014-09-03 | Inguran, LLC | Apparatus and methods for providing sex-sorted animal sperm |
| NZ544103A (en) * | 2003-05-15 | 2010-10-29 | Xy Llc | Efficient haploid cell sorting for flow cytometer systems |
| US7910523B2 (en) | 2003-05-23 | 2011-03-22 | Board Of Regents, The University Of Texas System | Structure based and combinatorially selected oligonucleoside phosphorothioate and phosphorodithioate aptamer targeting AP-1 transcription factors |
| US7701193B2 (en) * | 2003-09-02 | 2010-04-20 | Chempaq A/S | Pulse height analyser |
| WO2005095590A2 (en) | 2004-03-29 | 2005-10-13 | Monsanto Technology Llc | Sperm suspensions for sorting into x or y chromosome-bearing enriched populations |
| BRPI0513685A (pt) | 2004-07-22 | 2008-05-13 | Monsanto Technology Llc | processo para enriquecimento de uma população de células de esperma |
| US9260693B2 (en) | 2004-12-03 | 2016-02-16 | Cytonome/St, Llc | Actuation of parallel microfluidic arrays |
| US7996188B2 (en) * | 2005-08-22 | 2011-08-09 | Accuri Cytometers, Inc. | User interface for a flow cytometer system |
| US8017402B2 (en) | 2006-03-08 | 2011-09-13 | Accuri Cytometers, Inc. | Fluidic system for a flow cytometer |
| US8303894B2 (en) * | 2005-10-13 | 2012-11-06 | Accuri Cytometers, Inc. | Detection and fluidic system of a flow cytometer |
| US7780916B2 (en) * | 2006-03-08 | 2010-08-24 | Accuri Cytometers, Inc. | Flow cytometer system with unclogging feature |
| US8283177B2 (en) * | 2006-03-08 | 2012-10-09 | Accuri Cytometers, Inc. | Fluidic system with washing capabilities for a flow cytometer |
| DE102006021487B3 (de) * | 2006-05-05 | 2007-09-06 | Parsum Gmbh | Verfahren und Vorrichtung zur Bestimmung der in einem Partikelstrom enthaltenen Partikel |
| US8077310B2 (en) * | 2006-08-30 | 2011-12-13 | Accuri Cytometers, Inc. | System and method of capturing multiple source excitations from a single location on a flow channel |
| US8715573B2 (en) * | 2006-10-13 | 2014-05-06 | Accuri Cytometers, Inc. | Fluidic system for a flow cytometer with temporal processing |
| US8445286B2 (en) * | 2006-11-07 | 2013-05-21 | Accuri Cytometers, Inc. | Flow cell for a flow cytometer system |
| US7739060B2 (en) * | 2006-12-22 | 2010-06-15 | Accuri Cytometers, Inc. | Detection system and user interface for a flow cytometer system |
| JP5385161B2 (ja) | 2007-03-23 | 2014-01-08 | ベックマン コールター, インコーポレイテッド | フローサイトメトリに関する用途についてのマルチゲインアダプティブリニア処理およびゲート制御されたデジタルシステム |
| US8432541B2 (en) * | 2007-12-17 | 2013-04-30 | Accuri Cytometers, Inc. | Optical system for a flow cytometer with an interrogation zone |
| US8507279B2 (en) * | 2009-06-02 | 2013-08-13 | Accuri Cytometers, Inc. | System and method of verification of a prepared sample for a flow cytometer |
| US8004674B2 (en) * | 2009-06-02 | 2011-08-23 | Accuri Cytometers, Inc. | Data collection system and method for a flow cytometer |
| US8589851B2 (en) * | 2009-12-15 | 2013-11-19 | Memoir Systems, Inc. | Intelligent memory system compiler |
| WO2011106402A1 (en) * | 2010-02-23 | 2011-09-01 | Accuri Cytometers, Inc. | Method and system for detecting fluorochromes in a flow cytometer |
| WO2011159708A1 (en) | 2010-06-14 | 2011-12-22 | Accuri Cytometers, Inc. | System and method for creating a flow cytometer network |
| WO2012061155A2 (en) | 2010-10-25 | 2012-05-10 | Accuri Cytometers, Inc. | Systems and user interface for collecting a data set in a flow cytometer |
| EP3035031B1 (en) * | 2010-12-03 | 2022-06-01 | Cellply S.R.L. | Microanalysis of cellular function |
| US9753026B1 (en) | 2012-12-31 | 2017-09-05 | Techshot, Inc. | Cell processing cartridge for miniature cytometer |
| JP6338597B2 (ja) | 2013-01-09 | 2018-06-06 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアThe Regents Of The University Of California | 無線周波数多重励起を用いた蛍光イメージングのための装置及び方法 |
| EP3120130B1 (en) | 2014-03-18 | 2023-07-26 | The Regents of the University of California | Parallel flow cytometer using radiofrequency mulitplexing, and method |
| US9596349B1 (en) | 2015-06-29 | 2017-03-14 | State Farm Mutual Automobile Insurance Company | Voice and speech recognition for call center feedback and quality assurance |
| EP3362778B1 (en) | 2015-10-13 | 2022-08-03 | Omega Biosystems Incorporated | Multi-modal fluorescence imaging flow cytometry system |
| WO2017161247A1 (en) * | 2016-03-17 | 2017-09-21 | Bd Biosciences | Cell sorting using a high throughput fluorescence flow cytometer |
| GB2566847B (en) | 2016-05-19 | 2022-04-20 | Univ Leland Stanford Junior | Systems and methods for automated single cell cytological classification in flow |
| WO2017201546A1 (en) * | 2016-05-20 | 2017-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for automated single cell cytological classification in flow |
| JP6795554B2 (ja) * | 2018-07-10 | 2020-12-02 | 新東工業株式会社 | 計量装置 |
| US10611995B2 (en) | 2018-08-15 | 2020-04-07 | Deepcell, Inc. | Systems and methods for particle analysis |
| US11815507B2 (en) | 2018-08-15 | 2023-11-14 | Deepcell, Inc. | Systems and methods for particle analysis |
| EP3908824B1 (en) | 2019-01-11 | 2025-09-10 | Becton, Dickinson and Company | Optimized sorting gates |
| WO2021007075A1 (en) | 2019-07-10 | 2021-01-14 | Becton, Dickinson And Company | Reconfigurable integrated circuits for adjusting cell sorting classification |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2088111A1 (enExample) * | 1970-05-20 | 1972-01-07 | Coultronics France | |
| US3757213A (en) * | 1970-05-25 | 1973-09-04 | Coulter Electronics | Ntrol particle size analyzing apparatus and method using threshold level co |
| US3838549A (en) * | 1973-03-29 | 1974-10-01 | Fmc Corp | Packaging method |
| US4052596A (en) * | 1974-12-23 | 1977-10-04 | Hycel, Inc. | Automatic hematology analyzer |
| US4115806A (en) * | 1975-05-23 | 1978-09-19 | Bausch & Lomb Incorporated | Image analysis data transfer |
| US4318480A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device |
| JPS5658676A (en) * | 1979-10-18 | 1981-05-21 | Hajime Sangyo Kk | Inspection device |
| US4564598A (en) * | 1982-07-12 | 1986-01-14 | Syntex (U.S.A.) Inc. | Limited volume method for particle counting |
| JPS59174742A (ja) * | 1983-03-25 | 1984-10-03 | Agency Of Ind Science & Technol | 微小粒子を区分又は選別する方法及びその装置 |
| US4526276A (en) * | 1983-04-28 | 1985-07-02 | Becton, Dickinson And Company | Apparatus and method for sorting particles by gas actuation |
| JPS60213850A (ja) * | 1984-04-09 | 1985-10-26 | Hitachi Ltd | 粒子分析装置 |
| US4661913A (en) * | 1984-09-11 | 1987-04-28 | Becton, Dickinson And Company | Apparatus and method for the detection and classification of articles using flow cytometry techniques |
| US4727020A (en) * | 1985-02-25 | 1988-02-23 | Becton, Dickinson And Company | Method for analysis of subpopulations of blood cells |
| JPS62116260A (ja) * | 1985-11-15 | 1987-05-27 | Toa Medical Electronics Co Ltd | フロ−サイトメ−タ信号処理装置 |
| US4770992A (en) * | 1985-11-27 | 1988-09-13 | Den Engh Gerrit J Van | Detection of specific DNA sequences by flow cytometry |
| US4867908A (en) * | 1986-08-29 | 1989-09-19 | Becton, Dickinson And Company | Method and materials for calibrating flow cytometers and other analysis instruments |
| US5223398A (en) * | 1987-03-13 | 1993-06-29 | Coulter Corporation | Method for screening cells or formed bodies for enumeration of populations expressing selected characteristics |
| US4882284A (en) * | 1987-04-13 | 1989-11-21 | Ortho Pharmaceutical Corporation | Method for quantitating and differentiating white blood cells |
| JP2642632B2 (ja) * | 1987-07-03 | 1997-08-20 | 株式会社日立製作所 | 微粒子計測装置および微粒子計測方法 |
| JPS6435345A (en) * | 1987-07-31 | 1989-02-06 | Canon Kk | Particle analyzing device |
| DE3814811A1 (de) * | 1988-05-02 | 1989-11-16 | Merck Patent Gmbh | Verfahren und mittel zur differenzierung und bestimmung von leukozyten |
| WO1990010858A1 (en) * | 1989-03-06 | 1990-09-20 | Tsi Incorporated | Single particle detector using light scattering techniques |
| US4981580A (en) * | 1989-05-01 | 1991-01-01 | Coulter Corporation | Coincidence arbitration in a flow cytomery sorting system |
| US5156810A (en) * | 1989-06-15 | 1992-10-20 | Biocircuits Corporation | Biosensors employing electrical, optical and mechanical signals |
| US5030002A (en) * | 1989-08-11 | 1991-07-09 | Becton, Dickinson And Company | Method and apparatus for sorting particles with a moving catcher tube |
| US5199576A (en) * | 1991-04-05 | 1993-04-06 | University Of Rochester | System for flexibly sorting particles |
-
1991
- 1991-03-18 US US07/671,009 patent/US5204884A/en not_active Expired - Fee Related
-
1992
- 1992-03-18 WO PCT/US1992/002338 patent/WO1992016829A1/en not_active Ceased
- 1992-03-18 JP JP4508843A patent/JPH06507241A/ja active Pending
- 1992-03-18 EP EP92909044A patent/EP0576583B1/en not_active Expired - Lifetime
- 1992-03-18 DE DE69230033T patent/DE69230033T2/de not_active Expired - Fee Related
- 1992-03-18 CA CA002106191A patent/CA2106191A1/en not_active Abandoned
- 1992-03-18 AT AT92909044T patent/ATE184993T1/de not_active IP Right Cessation
- 1992-03-18 EP EP99103729A patent/EP0924510A1/en not_active Withdrawn
-
1996
- 1996-08-23 US US08/702,209 patent/US5804143A/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7043500B2 (en) | 2001-04-25 | 2006-05-09 | Board Of Regents, The University Of Texas Syxtem | Subtractive clustering for use in analysis of data |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0924510A1 (en) | 1999-06-23 |
| ATE184993T1 (de) | 1999-10-15 |
| JPH06507241A (ja) | 1994-08-11 |
| DE69230033D1 (de) | 1999-10-28 |
| EP0576583B1 (en) | 1999-09-22 |
| WO1992016829A1 (en) | 1992-10-01 |
| EP0576583A1 (en) | 1994-01-05 |
| US5804143A (en) | 1998-09-08 |
| DE69230033T2 (de) | 2000-06-08 |
| US5204884A (en) | 1993-04-20 |
| EP0576583A4 (enExample) | 1994-04-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |