CA2094822A1 - Pseudopentapeptides presentant une activite immunomodulatoire - Google Patents

Pseudopentapeptides presentant une activite immunomodulatoire

Info

Publication number
CA2094822A1
CA2094822A1 CA002094822A CA2094822A CA2094822A1 CA 2094822 A1 CA2094822 A1 CA 2094822A1 CA 002094822 A CA002094822 A CA 002094822A CA 2094822 A CA2094822 A CA 2094822A CA 2094822 A1 CA2094822 A1 CA 2094822A1
Authority
CA
Canada
Prior art keywords
mmol
residue
group
asp
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002094822A
Other languages
English (en)
Inventor
Joseph I. Degraw
Ronald Almquist
Charles Hiebert
R. Lane Smith
Itsuo Uchida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tobacco Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2094822A1 publication Critical patent/CA2094822A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • C07K14/662—Thymopoietins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
CA002094822A 1991-08-26 1992-08-19 Pseudopentapeptides presentant une activite immunomodulatoire Abandoned CA2094822A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US74988691A 1991-08-26 1991-08-26
US749,886 1991-08-26
US92060192A 1992-08-03 1992-08-03
US920,601 1992-08-03

Publications (1)

Publication Number Publication Date
CA2094822A1 true CA2094822A1 (fr) 1993-02-27

Family

ID=27115189

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002094822A Abandoned CA2094822A1 (fr) 1991-08-26 1992-08-19 Pseudopentapeptides presentant une activite immunomodulatoire

Country Status (5)

Country Link
EP (1) EP0556405A1 (fr)
JP (1) JPH06501961A (fr)
KR (1) KR930702383A (fr)
CA (1) CA2094822A1 (fr)
WO (1) WO1993004080A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744485A (en) * 1994-03-25 1998-04-28 Vertex Pharmaceuticals Incorporated Carbamates and ureas as modifiers of multi-drug resistance
FR2763071B1 (fr) * 1997-05-07 2003-05-16 Centre Nat Rech Scient Analogues peptidiques, et leurs utilisations notamment dans des compositions pharmaceutiques et pour le diagnostic
EP2513113B1 (fr) 2009-12-18 2018-08-01 Idenix Pharmaceuticals LLC Inhibiteurs du virus de l'hépatite c à base de 5,5-arylène ou hétéroarylène condensé

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ229004A (en) * 1988-05-19 1993-09-27 Immunobiology Res Inst Inc Tetrapeptides having t cell helper acitivity
IT1229658B (it) * 1989-04-21 1991-09-06 Eniricerche Spa Analoghi della timopentina retro-inversi ad uno o piu' legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.

Also Published As

Publication number Publication date
KR930702383A (ko) 1993-09-08
EP0556405A1 (fr) 1993-08-25
JPH06501961A (ja) 1994-03-03
WO1993004080A1 (fr) 1993-03-04

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Legal Events

Date Code Title Description
FZDE Dead