CA2089336A1 - Method for processing and preserving collagen-based tissues for transplantation - Google Patents

Method for processing and preserving collagen-based tissues for transplantation

Info

Publication number
CA2089336A1
CA2089336A1 CA 2089336 CA2089336A CA2089336A1 CA 2089336 A1 CA2089336 A1 CA 2089336A1 CA 2089336 CA2089336 CA 2089336 CA 2089336 A CA2089336 A CA 2089336A CA 2089336 A1 CA2089336 A1 CA 2089336A1
Authority
CA
Canada
Prior art keywords
processing
transplantation
preserving
treatment
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2089336
Other languages
French (fr)
Other versions
CA2089336C (en
Inventor
Stephen A. Livesey
Anthony A. Del Campo
Abhijit Nag
Ken B. Nichols
Edward S. Griffey
Christopher Coleman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LifeCell Corp
Original Assignee
LifeCell Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/004,752 external-priority patent/US5336616A/en
Application filed by LifeCell Corp filed Critical LifeCell Corp
Publication of CA2089336A1 publication Critical patent/CA2089336A1/en
Application granted granted Critical
Publication of CA2089336C publication Critical patent/CA2089336C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A method for processing and preserving an acellular collagen-based tissue matrix for transplantation is disclosed. The method includes the steps of processing biological tissues with a stabilizing solution to reduce procurement damage, treatment with a processing solution to remove cells, treatment with a cryoprotectant solution followed by freezing, drying, storage and rehydration under conditions that preclude functionally significant damage and reconstitution with viable cells.
CA 2089336 1990-09-12 1993-02-11 Method for processing and preserving collagen-based tissues for transplantation Expired - Lifetime CA2089336C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US58158490A 1990-09-12 1990-09-12
US83513892A 1992-02-12 1992-02-12
US07/835,138 1992-02-12
US08/004,752 US5336616A (en) 1990-09-12 1993-02-02 Method for processing and preserving collagen-based tissues for transplantation
US08/004,752 1993-02-02

Publications (2)

Publication Number Publication Date
CA2089336A1 true CA2089336A1 (en) 1993-08-13
CA2089336C CA2089336C (en) 2000-04-25

Family

ID=27357699

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2089336 Expired - Lifetime CA2089336C (en) 1990-09-12 1993-02-11 Method for processing and preserving collagen-based tissues for transplantation

Country Status (1)

Country Link
CA (1) CA2089336C (en)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996018293A1 (en) * 1994-12-12 1996-06-20 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5554497A (en) * 1994-12-12 1996-09-10 Charlotte-Mecklenburg Hospital Authority Cardioplegic solution for arresting an organ
US5595571A (en) * 1994-04-18 1997-01-21 Hancock Jaffe Laboratories Biological material pre-fixation treatment
US7358284B2 (en) 1998-06-19 2008-04-15 Lifecell Corporation Particulate acellular tissue matrix
CN110072992A (en) * 2016-12-14 2019-07-30 株式会社大塚制药工场 Mammalian cell freezen protective liquid
CN113396894A (en) * 2021-07-06 2021-09-17 南方医科大学南方医院 Composite freezing medium suitable for unit hair follicle preservation and preparation method and application thereof
CN118987350A (en) * 2024-07-05 2024-11-22 爱博诺德(北京)医疗科技股份有限公司 Acellular matrix scaffold material and preparation method and application thereof

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595571A (en) * 1994-04-18 1997-01-21 Hancock Jaffe Laboratories Biological material pre-fixation treatment
US5720777A (en) * 1994-04-18 1998-02-24 Hancock Jaffee Laboratories Biological material pre-fixation treatment
US5843180A (en) * 1994-04-18 1998-12-01 Hancock Jaffe Laboratories Method of treating a mammal having a defective heart valve
US5843181A (en) * 1994-04-18 1998-12-01 Hancock Jaffe Laboratories Biological material pre-fixation treatment
WO1996018293A1 (en) * 1994-12-12 1996-06-20 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
US5554497A (en) * 1994-12-12 1996-09-10 Charlotte-Mecklenburg Hospital Authority Cardioplegic solution for arresting an organ
US7358284B2 (en) 1998-06-19 2008-04-15 Lifecell Corporation Particulate acellular tissue matrix
CN110072992A (en) * 2016-12-14 2019-07-30 株式会社大塚制药工场 Mammalian cell freezen protective liquid
EP3556849A4 (en) * 2016-12-14 2020-08-19 Otsuka Pharmaceutical Factory, Inc. Mammalian Cryopreservation Fluid
AU2017377309B2 (en) * 2016-12-14 2021-05-27 Otsuka Pharmaceutical Factory, Inc. Mammalian cell cryopreservation liquid
AU2017377309B9 (en) * 2016-12-14 2021-06-03 Otsuka Pharmaceutical Factory, Inc. Mammalian cell cryopreservation liquid
US11889829B2 (en) 2016-12-14 2024-02-06 Otsuka Pharmaceutical Factory, Inc. Mammalian cell cryopreservation liquid
CN113396894A (en) * 2021-07-06 2021-09-17 南方医科大学南方医院 Composite freezing medium suitable for unit hair follicle preservation and preparation method and application thereof
CN118987350A (en) * 2024-07-05 2024-11-22 爱博诺德(北京)医疗科技股份有限公司 Acellular matrix scaffold material and preparation method and application thereof
CN118987350B (en) * 2024-07-05 2025-05-16 爱博诺德(北京)医疗科技股份有限公司 A decellularized matrix scaffold material and its preparation method and application

Also Published As

Publication number Publication date
CA2089336C (en) 2000-04-25

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Effective date: 20130211