CA2089162A1 - Onset of antiestrogen resistance in breast cancer - Google Patents

Onset of antiestrogen resistance in breast cancer

Info

Publication number
CA2089162A1
CA2089162A1 CA002089162A CA2089162A CA2089162A1 CA 2089162 A1 CA2089162 A1 CA 2089162A1 CA 002089162 A CA002089162 A CA 002089162A CA 2089162 A CA2089162 A CA 2089162A CA 2089162 A1 CA2089162 A1 CA 2089162A1
Authority
CA
Canada
Prior art keywords
tamoxifen
treatment
trans
cis
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002089162A
Other languages
English (en)
French (fr)
Inventor
C. Kent Osborne
Michael W. Degregorio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
University of Texas System
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2089162A1 publication Critical patent/CA2089162A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/57515—

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002089162A 1990-09-05 1991-09-04 Onset of antiestrogen resistance in breast cancer Abandoned CA2089162A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/577,790 US5119827A (en) 1990-09-05 1990-09-05 Mechanisms of antiestrogen resistance in breast cancer
US577,790 1990-09-05

Publications (1)

Publication Number Publication Date
CA2089162A1 true CA2089162A1 (en) 1992-03-06

Family

ID=24310178

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002089162A Abandoned CA2089162A1 (en) 1990-09-05 1991-09-04 Onset of antiestrogen resistance in breast cancer

Country Status (4)

Country Link
US (2) US5119827A (enExample)
EP (1) EP0547141A1 (enExample)
CA (1) CA2089162A1 (enExample)
WO (1) WO1992003973A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5119827A (en) * 1990-09-05 1992-06-09 Board Of Regents, The University Of Texas System Mechanisms of antiestrogen resistance in breast cancer
US5704045A (en) * 1995-01-09 1997-12-30 King; Douglas L. System and method of risk transfer and risk diversification including means to assure with assurance of timely payment and segregation of the interests of capital
US5742775A (en) * 1995-01-18 1998-04-21 King; Douglas L. Method and apparatus of creating financial instrument and administering an adjustable rate loan system
DE19628298C2 (de) * 1996-07-12 2002-04-11 Max Delbrueck Centrum Verfahren zum Nachweis einer Hormon- bzw. Antihormonresistenz bei Tumoren
WO1999006831A2 (en) * 1997-07-29 1999-02-11 Dorssers Lambert C J Breast cancer resistance genes, methods for their detection and uses thereof
CA2301032C (en) 1997-08-15 2009-01-13 Duke University A method of preventing or treating estrogen-dependent diseases and disorders
AU3105700A (en) * 1998-12-08 2000-06-26 Board Of Regents, The University Of Texas System Methods for detection of antiestrogen-resistant breast cancer
WO2004035805A2 (en) * 2002-05-17 2004-04-29 Baylor College Of Medicine Differential patterns of gene expression that predict for docetaxel chemosensitivity and chemoresistance
RU2232391C2 (ru) * 2002-09-05 2004-07-10 ООО "Медицинская диагностика" Способ дифференциальной диагностики злокачественных новообразований и соматических незлокачественных заболеваний
WO2005042766A2 (en) * 2003-10-31 2005-05-12 Molecular Targeting Technologies, Inc. Technetium-99m glucarate methods of use for monitoring tissues
US7829291B2 (en) * 2005-02-17 2010-11-09 Vanderbilt University In situ analysis of tissues
WO2011072244A1 (en) * 2009-12-10 2011-06-16 Mount Sinai School Of Medicine Of New York University Method of treatment of breast cancer with tamoxifen
AU2015259294A1 (en) * 2014-05-12 2016-12-01 Quest Diagnostics Investments Llc Quantitation of tamoxifen and metabolites thereof by mass spectrometry
WO2018045208A1 (en) * 2016-09-02 2018-03-08 Board Of Regents, The University Of Texas System Collection probe and methods for the use thereof
US10643832B2 (en) 2016-09-02 2020-05-05 Board Of Regents, The University Of Texas System Collection probe and methods for the use thereof
MX2020005448A (es) 2017-11-27 2020-08-27 Univ Texas Sonda de recoleccion minimamente invasiva y metodos para el uso de esta.
EP3914891A4 (en) 2019-01-25 2022-09-28 Board of Regents, The University of Texas System DEVICE AND METHOD FOR CLEANING AND/OR REPLACING MEDICAL DEVICES

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558373B1 (fr) * 1984-01-20 1987-07-03 Mauvais Jarvis Pierre Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee
US5023234A (en) * 1985-02-08 1991-06-11 Fernand Labrie Combination male breast cancer therapy
US5030417A (en) * 1984-09-19 1991-07-09 Mayo Foundation For Medical Education And Research Method and kit to assay for steroid receptor functionality in cancerous cells
US4806464A (en) * 1984-09-19 1989-02-21 Mayo Foundation For Medical Education And Research Nuclear binding assay for steroid receptor functionality in cancerous cells
AU8123787A (en) * 1986-11-17 1988-05-19 Oncotech Method to monitor and circumvent acquired resistance to chemotherapy in humans
AU2253688A (en) * 1987-07-24 1989-03-01 Xoma Corporation Methods for breast cancer detection
US5119827A (en) * 1990-09-05 1992-06-09 Board Of Regents, The University Of Texas System Mechanisms of antiestrogen resistance in breast cancer

Also Published As

Publication number Publication date
US5384260A (en) 1995-01-24
EP0547141A4 (enExample) 1994-01-05
US5119827A (en) 1992-06-09
EP0547141A1 (en) 1993-06-23
WO1992003973A1 (en) 1992-03-19

Similar Documents

Publication Publication Date Title
US5384260A (en) Detection of onset of antiestrogen resistance in breast cancer
Wiebe et al. Identification of estrogenic tamoxifen metabolite (s) in tamoxifen-resistant human breast tumors.
Onn et al. Effects of intraventricular 6-hydroxydopamine on the dopaminergic innervation of striatum: histochemical and neurochemical analysis
Lien et al. Identification of 4-hydroxy-N-desmethyltamoxifen as a metabolite of tamoxifen in human bile
Lazarevic et al. Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial
US4859585A (en) In-vitro methods for identifying compositions which are agonists and antagonists of estrogens
Muir Flax lignansanalytical methods and how they influence our understanding of biological activity
Murphy et al. Analysis of tamoxifen and its metabolites in human plasma by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM)
Levine et al. Distribution of venlafaxine in three postmortem cases
Evans et al. Analysis of cocaine and cocaine metabolites by high pressure liquid chromatography
US20170176446A1 (en) Methods for Determining the Oncogenic Condition of Cell, Uses Thereof, and Methods for Treating Cancer
Hatano et al. D2-dopamine receptor specific brain uptake of carbon-11-labeled YM-09151-2
Verhagen et al. Metabolism of a [18F] fluorine labeled progestin (21-[18F] fluoro-16α-ethyl-19-norprogesterone) in humans: a clue for future investigations
AU2001284753A1 (en) Detection of COX-2 activity and anandamide metabolites
JPH06509221A (ja) 治療に対する腫瘍反応の予測方法
Liehr et al. Inhibition of estrogen-induced renal carcinogenesis in male Syrian hamsters by tamoxifen without decrease in DNA adduct levels
Wolf et al. Estrogen and progestin receptors in human prostatic carcinoma
Murphy et al. Analysis of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen levels in cytosol and KCl-nuclear extracts of breast tumours from tamoxifen treated patients by gas chromatoraphy-mass spectrometry (GC-MS) using selected ion monitoring (SIM)
Mihailescu et al. Identification of tamoxifen and metabolites in human male urine by GC/MS
Bowman et al. Hypothalamic, pituitary and uterine cytoplasmic and nuclear oestrogen receptors and their relationship to the serum concentration of tamoxifen and its metabolite, 4-hydroxytamoxifen, in the ovariectomized rat
Gal et al. Disposition of (R, S)-tocainide. Some stereoselective aspects.
Boros et al. Isofenphos induced metabolic changes in K562 myeloid blast cells
Muskiet et al. Determination of some L-3, 4-dihydroxyphenylalanine and dopamine metabolites in urine by means of mass fragmentography.
Fuhrman et al. Soy intake is associated with increased 2-hydroxylation and decreased 16α-hydroxylation of estrogens in Asian-American women
Lyman et al. Metabolism of nonsteroidal antiestrogens

Legal Events

Date Code Title Description
FZDE Discontinued