CA2089162A1 - Onset of antiestrogen resistance in breast cancer - Google Patents
Onset of antiestrogen resistance in breast cancerInfo
- Publication number
- CA2089162A1 CA2089162A1 CA002089162A CA2089162A CA2089162A1 CA 2089162 A1 CA2089162 A1 CA 2089162A1 CA 002089162 A CA002089162 A CA 002089162A CA 2089162 A CA2089162 A CA 2089162A CA 2089162 A1 CA2089162 A1 CA 2089162A1
- Authority
- CA
- Canada
- Prior art keywords
- tamoxifen
- treatment
- trans
- cis
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
-
- G01N33/57515—
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US577,790 | 1990-09-05 | ||
| US07/577,790 US5119827A (en) | 1990-09-05 | 1990-09-05 | Mechanisms of antiestrogen resistance in breast cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2089162A1 true CA2089162A1 (en) | 1992-03-06 |
Family
ID=24310178
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002089162A Abandoned CA2089162A1 (en) | 1990-09-05 | 1991-09-04 | Onset of antiestrogen resistance in breast cancer |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US5119827A (enExample) |
| EP (1) | EP0547141A1 (enExample) |
| CA (1) | CA2089162A1 (enExample) |
| WO (1) | WO1992003973A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5119827A (en) * | 1990-09-05 | 1992-06-09 | Board Of Regents, The University Of Texas System | Mechanisms of antiestrogen resistance in breast cancer |
| US5704045A (en) * | 1995-01-09 | 1997-12-30 | King; Douglas L. | System and method of risk transfer and risk diversification including means to assure with assurance of timely payment and segregation of the interests of capital |
| US5742775A (en) * | 1995-01-18 | 1998-04-21 | King; Douglas L. | Method and apparatus of creating financial instrument and administering an adjustable rate loan system |
| DE19628298C2 (de) * | 1996-07-12 | 2002-04-11 | Max Delbrueck Centrum | Verfahren zum Nachweis einer Hormon- bzw. Antihormonresistenz bei Tumoren |
| WO1999006831A2 (en) * | 1997-07-29 | 1999-02-11 | Dorssers Lambert C J | Breast cancer resistance genes, methods for their detection and uses thereof |
| DE69840126D1 (de) | 1997-08-15 | 2008-11-27 | Univ Duke | Verfahren zur prophylaxis oder behandlung von östrogen-abhängigen krankheiten |
| AU3105700A (en) * | 1998-12-08 | 2000-06-26 | Board Of Regents, The University Of Texas System | Methods for detection of antiestrogen-resistant breast cancer |
| MXPA04011424A (es) * | 2002-05-17 | 2005-02-17 | Baylor College Medicine | Patrones diferenciales de expresion genetica que predicen la quimioresistencia y quimiosensibilidad a docetaxel. |
| RU2232391C2 (ru) * | 2002-09-05 | 2004-07-10 | ООО "Медицинская диагностика" | Способ дифференциальной диагностики злокачественных новообразований и соматических незлокачественных заболеваний |
| US20050152835A1 (en) * | 2003-10-31 | 2005-07-14 | Pak Koon Y. | Technetium-99M glucarate methods of use for monitoring tissues |
| US7829291B2 (en) * | 2005-02-17 | 2010-11-09 | Vanderbilt University | In situ analysis of tissues |
| WO2011072244A1 (en) * | 2009-12-10 | 2011-06-16 | Mount Sinai School Of Medicine Of New York University | Method of treatment of breast cancer with tamoxifen |
| CN106537139B (zh) | 2014-05-12 | 2019-04-16 | 奎斯特诊断投资公司 | 通过质谱法定量他莫昔芬及其代谢物 |
| WO2018045208A1 (en) * | 2016-09-02 | 2018-03-08 | Board Of Regents, The University Of Texas System | Collection probe and methods for the use thereof |
| KR102543773B1 (ko) | 2016-09-02 | 2023-06-16 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 수집 프로브 및 이들의 사용 방법 |
| CN111566481A (zh) | 2017-11-27 | 2020-08-21 | 得克萨斯州大学系统董事会 | 微创收集探头及其使用方法 |
| WO2020154477A1 (en) | 2019-01-25 | 2020-07-30 | Board Of Regents, The University Of Texas System | Apparatus and methods for cleaning and/or exchanging medical devices |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2558373B1 (fr) * | 1984-01-20 | 1987-07-03 | Mauvais Jarvis Pierre | Medicament antioestrogene a base de 4-hydroxytamoxifene pour administration percutanee |
| US5023234A (en) * | 1985-02-08 | 1991-06-11 | Fernand Labrie | Combination male breast cancer therapy |
| US5030417A (en) * | 1984-09-19 | 1991-07-09 | Mayo Foundation For Medical Education And Research | Method and kit to assay for steroid receptor functionality in cancerous cells |
| US4806464A (en) * | 1984-09-19 | 1989-02-21 | Mayo Foundation For Medical Education And Research | Nuclear binding assay for steroid receptor functionality in cancerous cells |
| AU8123787A (en) * | 1986-11-17 | 1988-05-19 | Oncotech | Method to monitor and circumvent acquired resistance to chemotherapy in humans |
| AU2253688A (en) * | 1987-07-24 | 1989-03-01 | Xoma Corporation | Methods for breast cancer detection |
| US5119827A (en) * | 1990-09-05 | 1992-06-09 | Board Of Regents, The University Of Texas System | Mechanisms of antiestrogen resistance in breast cancer |
-
1990
- 1990-09-05 US US07/577,790 patent/US5119827A/en not_active Expired - Fee Related
-
1991
- 1991-09-04 EP EP91916623A patent/EP0547141A1/en not_active Withdrawn
- 1991-09-04 WO PCT/US1991/006323 patent/WO1992003973A1/en not_active Ceased
- 1991-09-04 CA CA002089162A patent/CA2089162A1/en not_active Abandoned
-
1993
- 1993-03-17 US US08/030,351 patent/US5384260A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1992003973A1 (en) | 1992-03-19 |
| EP0547141A4 (enExample) | 1994-01-05 |
| US5384260A (en) | 1995-01-24 |
| US5119827A (en) | 1992-06-09 |
| EP0547141A1 (en) | 1993-06-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5384260A (en) | Detection of onset of antiestrogen resistance in breast cancer | |
| Wiebe et al. | Identification of estrogenic tamoxifen metabolite (s) in tamoxifen-resistant human breast tumors. | |
| Onn et al. | Effects of intraventricular 6-hydroxydopamine on the dopaminergic innervation of striatum: histochemical and neurochemical analysis | |
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| Lien et al. | Identification of 4-hydroxy-N-desmethyltamoxifen as a metabolite of tamoxifen in human bile | |
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| Murphy et al. | Analysis of tamoxifen and its metabolites in human plasma by gas chromatography-mass spectrometry (GC-MS) using selected ion monitoring (SIM) | |
| Markaverich et al. | Leukotoxin diols from ground corncob bedding disrupt estrous cyclicity in rats and stimulate MCF-7 breast cancer cell proliferation | |
| Levine et al. | Distribution of venlafaxine in three postmortem cases | |
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| Hatano et al. | D2-dopamine receptor specific brain uptake of carbon-11-labeled YM-09151-2 | |
| Verhagen et al. | Metabolism of a [18F] fluorine labeled progestin (21-[18F] fluoro-16α-ethyl-19-norprogesterone) in humans: a clue for future investigations | |
| US20140221353A1 (en) | Methods for Determining the Oncogenic Condition of Cell, Uses Thereof, and Methods for Treating Cancer | |
| JPH06509221A (ja) | 治療に対する腫瘍反応の予測方法 | |
| Liehr et al. | Inhibition of estrogen-induced renal carcinogenesis in male Syrian hamsters by tamoxifen without decrease in DNA adduct levels | |
| Murphy et al. | Analysis of tamoxifen, N-desmethyltamoxifen and 4-hydroxytamoxifen levels in cytosol and KCl-nuclear extracts of breast tumours from tamoxifen treated patients by gas chromatoraphy-mass spectrometry (GC-MS) using selected ion monitoring (SIM) | |
| Mihailescu et al. | Identification of tamoxifen and metabolites in human male urine by GC/MS | |
| Bowman et al. | Hypothalamic, pituitary and uterine cytoplasmic and nuclear oestrogen receptors and their relationship to the serum concentration of tamoxifen and its metabolite, 4-hydroxytamoxifen, in the ovariectomized rat | |
| Lee et al. | Polyamine profiles in the urine of patients with leukemia | |
| Wolf et al. | Estrogen and progestin receptors in human prostatic carcinoma | |
| L’homme et al. | Time-resolved fluoroimmunoassay of plasma and urine O-desmethylangolensin | |
| Gal et al. | Disposition of (R, S)-tocainide. Some stereoselective aspects. | |
| Boros et al. | Isofenphos induced metabolic changes in K562 myeloid blast cells | |
| Fuhrman et al. | Soy intake is associated with increased 2-hydroxylation and decreased 16α-hydroxylation of estrogens in Asian-American women |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |