CA2087528A1 - Immunoglobulines chimeriques neutralisant le vih-1 - Google Patents
Immunoglobulines chimeriques neutralisant le vih-1Info
- Publication number
- CA2087528A1 CA2087528A1 CA002087528A CA2087528A CA2087528A1 CA 2087528 A1 CA2087528 A1 CA 2087528A1 CA 002087528 A CA002087528 A CA 002087528A CA 2087528 A CA2087528 A CA 2087528A CA 2087528 A1 CA2087528 A1 CA 2087528A1
- Authority
- CA
- Canada
- Prior art keywords
- chimeric
- cells
- antibody
- hiv
- antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 229960000907 methylthioninium chloride Drugs 0.000 description 1
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- 238000010369 molecular cloning Methods 0.000 description 1
- 239000003068 molecular probe Substances 0.000 description 1
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- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
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- 239000013600 plasmid vector Substances 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 210000002729 polyribosome Anatomy 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000001243 protein synthesis Methods 0.000 description 1
- 239000002213 purine nucleotide Substances 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
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- 230000010076 replication Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 102220065853 rs559756386 Human genes 0.000 description 1
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- 238000013207 serial dilution Methods 0.000 description 1
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- 239000007974 sodium acetate buffer Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1990/004048 WO1992001719A1 (fr) | 1990-07-18 | 1990-07-18 | Immunoglobulines chimeriques netralisant le hiv-1 |
| EP19900912204 EP0540512A4 (en) | 1990-07-18 | 1990-07-18 | Chimeric hiv-1-neutralizing immunoglobulins |
| AU61761/90A AU644811B2 (en) | 1990-07-18 | 1990-07-18 | Chimeric HIV-1-neutralizing immunoglobulins |
| CA002087528A CA2087528A1 (fr) | 1990-07-18 | 1990-07-18 | Immunoglobulines chimeriques neutralisant le vih-1 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1990/004048 WO1992001719A1 (fr) | 1990-07-18 | 1990-07-18 | Immunoglobulines chimeriques netralisant le hiv-1 |
| CA002087528A CA2087528A1 (fr) | 1990-07-18 | 1990-07-18 | Immunoglobulines chimeriques neutralisant le vih-1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2087528A1 true CA2087528A1 (fr) | 1992-01-19 |
Family
ID=4150996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002087528A Abandoned CA2087528A1 (fr) | 1990-07-18 | 1990-07-18 | Immunoglobulines chimeriques neutralisant le vih-1 |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0540512A4 (fr) |
| AU (1) | AU644811B2 (fr) |
| CA (1) | CA2087528A1 (fr) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0295803B1 (fr) * | 1987-05-29 | 1993-11-03 | Shuzo Matsushita | Anticorps monoclonaux |
-
1990
- 1990-07-18 AU AU61761/90A patent/AU644811B2/en not_active Ceased
- 1990-07-18 EP EP19900912204 patent/EP0540512A4/en not_active Withdrawn
- 1990-07-18 CA CA002087528A patent/CA2087528A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU644811B2 (en) | 1993-12-23 |
| EP0540512A4 (en) | 1993-06-30 |
| AU6176190A (en) | 1992-02-18 |
| EP0540512A1 (fr) | 1993-05-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |