CA2086100A1 - Substitutions regioselectives dans des cyclodextrines - Google Patents
Substitutions regioselectives dans des cyclodextrinesInfo
- Publication number
- CA2086100A1 CA2086100A1 CA2086100A CA2086100A CA2086100A1 CA 2086100 A1 CA2086100 A1 CA 2086100A1 CA 2086100 A CA2086100 A CA 2086100A CA 2086100 A CA2086100 A CA 2086100A CA 2086100 A1 CA2086100 A1 CA 2086100A1
- Authority
- CA
- Canada
- Prior art keywords
- cyclodextrin
- cyclodextrins
- regioselective
- substitutions
- cyclodextrins includes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Méthode pour augmenter la solubilité des cyclodextrines, consistant à faire réagir les cyclodextrines avec des amines dans des conditions de catalyse hétérogène, par exposition de ces cyclodextrines à de l'ammoniac et à du nickel de Raney, ou par leur sulfatation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/544,546 US5173481A (en) | 1989-04-03 | 1990-06-28 | Preparation of specifically substituted cyclodextrins |
US544,546 | 1990-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2086100A1 true CA2086100A1 (fr) | 1991-12-29 |
CA2086100C CA2086100C (fr) | 1998-09-08 |
Family
ID=24172617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002086100A Expired - Lifetime CA2086100C (fr) | 1990-06-28 | 1991-06-28 | Substitutions regioselectives dans des cyclodextrines |
Country Status (11)
Country | Link |
---|---|
US (1) | US5173481A (fr) |
EP (1) | EP0536318B1 (fr) |
JP (1) | JPH0762043B2 (fr) |
AT (1) | ATE157992T1 (fr) |
AU (1) | AU643551B2 (fr) |
CA (1) | CA2086100C (fr) |
DE (1) | DE69127624T2 (fr) |
DK (1) | DK0536318T3 (fr) |
ES (1) | ES2109271T3 (fr) |
GR (1) | GR3025620T3 (fr) |
WO (1) | WO1992000331A1 (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR927003647A (ko) * | 1990-11-30 | 1992-12-18 | 돕빵 인사쯔 가부시끼가이샤 | 시클로덱스트린유도체 및 시클로덱스트린 고정화 폴리머의 제조방법 |
ES2053399B1 (es) * | 1993-01-11 | 1995-02-16 | Univ Madrid Complutense | Procedimiento para la obtencion de derivados de beta-ciclodextrina. |
US5661040A (en) * | 1993-07-13 | 1997-08-26 | Abbott Laboratories | Fluorescent polymer labeled conjugates and intermediates |
US5985772A (en) | 1994-06-23 | 1999-11-16 | Cellresin Technologies, Llc | Packaging system comprising cellulosic web with a permeant barrier or contaminant trap |
US5776842A (en) | 1994-06-23 | 1998-07-07 | Cellresin Technologies, Llc | Cellulosic web with a contaminant barrier or trap |
US5492947A (en) | 1994-06-23 | 1996-02-20 | Aspen Research Corporation | Barrier material comprising a thermoplastic and a compatible cyclodextrin derivative |
DE4428654A1 (de) | 1994-08-12 | 1996-02-15 | Consortium Elektrochem Ind | Wasserlösliche Cyclodextrinderivate mit lipophilen Substituenten und Verfahren zu ihrer Herstellung |
US5569756A (en) * | 1995-03-21 | 1996-10-29 | American Maize-Products Company | Purification of chemically modified cyclodextrins |
US5882565A (en) | 1995-12-11 | 1999-03-16 | Cellresin Technologies, Llc | Barrier material comprising a thermoplastic and a compatible cyclodextrin derivative |
EP0954326B2 (fr) | 1996-04-19 | 2009-07-22 | Grifols Inc. | Procede d'inactivation de virus dans des proteines sanguines lyophilisees |
TWI242015B (en) | 1999-11-29 | 2005-10-21 | Akzo Nobel Nv | 6-mercapto-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block |
US20020146409A1 (en) * | 2001-01-30 | 2002-10-10 | Herring Steven W. | Methods for stabilizing lyophilized blood proteins |
US7385004B2 (en) | 2002-12-10 | 2008-06-10 | Cellresin Technologies, Llc | Enhanced lubrication in polyolefin closure with polyolefin grafted cyclodextrin |
US8129450B2 (en) | 2002-12-10 | 2012-03-06 | Cellresin Technologies, Llc | Articles having a polymer grafted cyclodextrin |
US7166671B2 (en) | 2002-12-10 | 2007-01-23 | Cellresin Technologies, Llc | Grafted cyclodextrin |
DE10344967B4 (de) * | 2003-09-07 | 2011-07-28 | Henkel AG & Co. KGaA, 40589 | Alkoxylgruppen-haltige Cyclodextrin-Derivate; Verfahren zu deren Herstellung und deren Verwendung |
CA2568010C (fr) | 2004-05-24 | 2012-09-18 | Cellresin Technologies, Llc | Materiaux barrieres greffes amphoteres |
US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
DK2814849T3 (da) | 2012-02-15 | 2020-03-09 | Cydex Pharmaceuticals Inc | Fremgangsmåde til fremstilling af cyclodextrin-derivater |
KR101633479B1 (ko) | 2012-02-28 | 2016-07-08 | 사이덱스 파마슈티칼스, 인크. | 알킬화된 시클로덱스트린 조성물 및 이의 제조 및 사용 방법 |
AU2013292647B2 (en) | 2012-07-18 | 2018-03-15 | Onyx Therapeutics, Inc. | Liposomal compositions of epoxyketone-based proteasome inhibitors |
MX360192B (es) | 2012-10-22 | 2018-10-24 | Cydex Pharmaceuticals Inc | Composiciones de ciclodextrinas alquiladas y procesos para preparar y usar las mismas. |
US10851184B2 (en) | 2014-08-22 | 2020-12-01 | Cydex Pharmaceuticals, Inc. | Fractionated alkylated cyclodextrin compositions and processes for preparing and using the same |
JP2019163344A (ja) * | 2016-07-25 | 2019-09-26 | 国立大学法人 東京大学 | 擬ポリロタキサン、ポリロタキサン、及びそれらの製造方法 |
EP3574047B1 (fr) | 2017-01-30 | 2024-03-06 | Bio-Rad Laboratories, Inc. | Compositions d'émulsion et leurs procédés d'utilisation |
CN111808299B (zh) * | 2020-07-02 | 2022-05-31 | 山东滨州智源生物科技有限公司 | 一种羟丙基倍他环糊精水溶液的制备方法 |
CN113845607A (zh) * | 2021-10-26 | 2021-12-28 | 波托菲诺(海南)实业有限公司 | 一种羟丙基-γ-环糊精的制备方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3459731A (en) * | 1966-12-16 | 1969-08-05 | Corn Products Co | Cyclodextrin polyethers and their production |
US3654370A (en) * | 1970-08-28 | 1972-04-04 | Jefferson Chem Co Inc | Process for preparing polyoxyalkylene polyamines |
JPS5036422A (fr) * | 1973-08-07 | 1975-04-05 | ||
US4020160A (en) * | 1975-08-15 | 1977-04-26 | American Cyanamid Company | Cyclodextrin sulfate salts as complement inhibitors |
FR2398425A1 (fr) * | 1977-07-18 | 1979-02-16 | Hehemann Guenter | Casque stereophonique |
US4124758A (en) * | 1977-08-29 | 1978-11-07 | Texaco Development Corporation | Aminated hydroxyalkyl cellulose |
US4247535A (en) * | 1979-11-05 | 1981-01-27 | American Cyanamid Company | Modified cyclodextrin sulfate salts as complement inhibitors |
DE3477929D1 (en) * | 1983-12-17 | 1989-06-01 | Hoechst Ag | Beta-cyclodextrin and process for its preparation |
EP0146841A3 (fr) * | 1983-12-17 | 1986-11-20 | Consortium für elektrochemische Industrie GmbH | Ether mixte de bêta-cyclodextrine soluble dans l'eau et procédé pour sa préparation |
US4727064A (en) * | 1984-04-25 | 1988-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Pharmaceutical preparations containing cyclodextrin derivatives |
US4912093A (en) * | 1986-10-01 | 1990-03-27 | Marion Laboratories, Inc. | Use of synthetic sulfated saccharides to enhance wound healing |
EP0240098A3 (fr) * | 1986-04-04 | 1989-05-10 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Oligo et Polysaccharides pour le traitement des maladies causées par des rétrovirus |
US4840991A (en) * | 1986-11-28 | 1989-06-20 | Desoto, Inc. | Aqueous dispersions of partially cross-linked emulsion copolymers |
US4877778A (en) * | 1987-07-01 | 1989-10-31 | The Children's Medical Center Corporation | Method of enhancing lipophile transport using cyclodextrin derivatives |
IE64346B1 (en) * | 1988-01-19 | 1995-07-26 | Moses Judah Folkman | Growth inhibiting agent and the use thereof |
US5019562A (en) * | 1988-01-19 | 1991-05-28 | The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation | Growth inhibiting agent and the use thereof |
MY106598A (en) * | 1988-08-31 | 1995-06-30 | Australian Commercial Res & Development Ltd | Compositions and methods for drug delivery and chromatography. |
-
1990
- 1990-06-28 US US07/544,546 patent/US5173481A/en not_active Expired - Lifetime
-
1991
- 1991-06-28 AU AU82347/91A patent/AU643551B2/en not_active Ceased
- 1991-06-28 ES ES91913620T patent/ES2109271T3/es not_active Expired - Lifetime
- 1991-06-28 EP EP91913620A patent/EP0536318B1/fr not_active Expired - Lifetime
- 1991-06-28 AT AT91913620T patent/ATE157992T1/de not_active IP Right Cessation
- 1991-06-28 DE DE69127624T patent/DE69127624T2/de not_active Expired - Fee Related
- 1991-06-28 DK DK91913620.0T patent/DK0536318T3/da active
- 1991-06-28 CA CA002086100A patent/CA2086100C/fr not_active Expired - Lifetime
- 1991-06-28 JP JP3512648A patent/JPH0762043B2/ja not_active Expired - Lifetime
- 1991-06-28 WO PCT/US1991/004651 patent/WO1992000331A1/fr active IP Right Grant
-
1997
- 1997-12-08 GR GR970402925T patent/GR3025620T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0536318A1 (fr) | 1993-04-14 |
AU643551B2 (en) | 1993-11-18 |
AU8234791A (en) | 1992-01-23 |
EP0536318A4 (en) | 1993-11-18 |
US5173481A (en) | 1992-12-22 |
JPH0762043B2 (ja) | 1995-07-05 |
DE69127624T2 (de) | 1998-03-12 |
JPH05507757A (ja) | 1993-11-04 |
ATE157992T1 (de) | 1997-09-15 |
DK0536318T3 (da) | 1998-04-27 |
WO1992000331A1 (fr) | 1992-01-09 |
EP0536318B1 (fr) | 1997-09-10 |
ES2109271T3 (es) | 1998-01-16 |
DE69127624D1 (de) | 1997-10-16 |
GR3025620T3 (en) | 1998-03-31 |
CA2086100C (fr) | 1998-09-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed | ||
MKEC | Expiry (correction) |
Effective date: 20121202 |