CA2082495A1 - A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols - Google Patents

A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols

Info

Publication number
CA2082495A1
CA2082495A1 CA002082495A CA2082495A CA2082495A1 CA 2082495 A1 CA2082495 A1 CA 2082495A1 CA 002082495 A CA002082495 A CA 002082495A CA 2082495 A CA2082495 A CA 2082495A CA 2082495 A1 CA2082495 A1 CA 2082495A1
Authority
CA
Canada
Prior art keywords
glycofurols
pharmaceutical preparation
ethylene glycols
preparation containing
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002082495A
Other languages
French (fr)
Other versions
CA2082495C (en
Inventor
Erik Bechgaard
Sveinbjorn Gizurarson
Rolf K. Hjortkjaer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lyfjathroun Hf Biopharmaceuticals
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK117090A external-priority patent/DK117090D0/en
Priority claimed from DK207590A external-priority patent/DK207590D0/en
Application filed by Individual filed Critical Individual
Priority claimed from PCT/DK1991/000119 external-priority patent/WO1991016929A1/en
Publication of CA2082495A1 publication Critical patent/CA2082495A1/en
Application granted granted Critical
Publication of CA2082495C publication Critical patent/CA2082495C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A pharmaceutical preparation for application of biologically active substance(s) to a mucosal membrane of a mammal comprising one or more substance(s) selected from the group consisting of n-glycofurols represented by formula (I), wherein n is 1 to 8, and n-ethylene glycols represented by the formula (II): H(OCH2CH2)p OH, wherein p is 1 to 14, produces a high plasma concentration of the pharmaceutically active substance(s) nearly as rapid as by i.v. administration.
CA002082495A 1990-05-10 1991-05-03 A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols Expired - Fee Related CA2082495C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK117090A DK117090D0 (en) 1990-05-10 1990-05-10 COMPOSITION FOR INTRANASAL ADMINISTRATION OF BIOL OGICALLY ACTIVE BENZODIAZEPINE COMPOUNDS
DK1170/90 1990-05-10
DK207590A DK207590D0 (en) 1990-08-30 1990-08-30 PHARMACEUTICAL PREPARATION
DK2075/90 1990-08-30
PCT/DK1991/000119 WO1991016929A1 (en) 1990-05-10 1991-05-03 A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols

Publications (2)

Publication Number Publication Date
CA2082495A1 true CA2082495A1 (en) 1991-11-11
CA2082495C CA2082495C (en) 2006-10-03

Family

ID=37101712

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002082495A Expired - Fee Related CA2082495C (en) 1990-05-10 1991-05-03 A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols

Country Status (1)

Country Link
CA (1) CA2082495C (en)

Also Published As

Publication number Publication date
CA2082495C (en) 2006-10-03

Similar Documents

Publication Publication Date Title
AU7880991A (en) A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
EA199600104A1 (en) INCREASED BIOAVAILABILITY OF BIOLOGICALLY ACTIVE COMPOUNDS WHEN BINDING WITH DERIVATIVES OF POLYPYROLORARCARBOXAMIDONAPHTHALIC ACID
MD1233B1 (en) Erythromycin derivatives, process for their preparation and pharmaceutical composition on base thereof
CA2044746A1 (en) Polypeptide compound and a process for preparation thereof
SE8702907D0 (en) STABLE PHARMACEUTICAL PREPARATION CONTAINING GRANULOCYTE COLONY STIMULATING FACTOR AND PROCESS FOR PRODUCING THE SAME
DE3564566D1 (en) Quinone derivatives, method and use of preparing same, and pharmaceutical composition
HUT47217A (en) Process for producing pharmaceutical compositions containing indol derivatives as active components
EP0564739A3 (en)
IE873125L (en) Benzimidazole derivatives
GR3017128T3 (en) Treatment of hiv infections and compounds useful therein.
HU9400430D0 (en) New pyrazine derivatives, their preparation and pharmaceutical compositions containing them
CA2040982A1 (en) N-(3-fluoro-2-phosphonylmethoxypropyl) derivatives of purine and pyrimidine heterocyclic bases, their preparation and use
IL105646A0 (en) Sulfonylbenzyl-substituted benzo-and pyridopyridones,their preparation and pharmaceutical compositions containing them
HUT38097A (en) Process for preparing substituted benzopyrans and pharmaceutical compositions containing them as active substances
NO177714C (en) Analogous Process for Preparing Therapeutically Active Peptide Derivatives
IE894050L (en) Compound with gastric acid inhibitory effect and process for¹its preparation
CA2082495A1 (en) A pharmaceutical preparation containing n-glycofurols and n-ethylene glycols
ES2145740T3 (en) GROWTH, PREPARATION AND USE FACTOR COMPOSITIONS.
AU7939491A (en) Ws7622a mono- or di-sulfate, process for preparation thereof and use thereof
NO174963C (en) Analogous Process for the Preparation of Therapeutically Active 8-Fluoroanthracycling Glucosides
CA2022323A1 (en) Excretion of potassium ion by prostanoic acid derivatives
JPS57106644A (en) Farnesence derivative, mucosa stabilizer comprising it as active ingredient, and its preparation
IT1270122B (en) 6-BENZYL-4-OXYPYRIMIDIN REPLACED, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
KR890014745A (en) FR-900493 compound, its preparation method and pharmaceutical composition containing same
JPS5742620A (en) Novel antiulcer agent

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed