CA2075501A1 - Device for use with the inhalation of powdered materials contained in rod-shaped capsules - Google Patents
Device for use with the inhalation of powdered materials contained in rod-shaped capsulesInfo
- Publication number
- CA2075501A1 CA2075501A1 CA002075501A CA2075501A CA2075501A1 CA 2075501 A1 CA2075501 A1 CA 2075501A1 CA 002075501 A CA002075501 A CA 002075501A CA 2075501 A CA2075501 A CA 2075501A CA 2075501 A1 CA2075501 A1 CA 2075501A1
- Authority
- CA
- Canada
- Prior art keywords
- mouth piece
- capsule
- mixing chamber
- receiving cavity
- cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Abstract
The invention relates to a device for use with the inhalation of powdered materials contained in rod-shaped capsules, having two parts (2, 3) which may be pivoted one relative to the other, and provided with a mixing chamber (7) having substantially tangentially directed air inlet openings, said mixing chamber having one end in communication with a mouth piece (6) and the other end in communication with a capsule receiving cavity (26), the latter being formed in conformity with the longitudinal sectional shape of a capsule and having at at least one longitudinal end a passage opening (27) for a transversely (= in the longitudinal direction of the capsule receiving cavity) reciprocating piercing needle, and wherein the part (2) of the device comprising the mouth piece (6) is mounted to pivot relative to the capsule receiving cavity comprising part (3) of the device between a closed ready for use-position and an opened position permitting the insertion of a capsule. In accordance with the invention the mouth piece (6) is integrally formed with the mixing chamber (7), whereas the capsule receiving cavity (26) is provided in a bottom section (25) which closes the mixing chamber (7) in the closed or ready for use-position and is making part of said other part (3) of the device.
Description
WO 92/10230 ~7~ f~. PC~r/NL91/00259 Title: A device for use with the inhalation of Fch~n3d materials conta med in rcd-shaped cap6ules.
The invention relates to a devi oe Por use with the inhalation of powdered materials contained in rod-s~ped capsules, of the type, cG~prising a mlx1ng chan~x~r havlng s~k~ ntially tangentially direx~ed air inlet cpenings, said mlx m g ch2mber having one end in ccmmunica-tion with a ~cuth piece and the ct~Er end in ccmmunication with ac ~ e receiving cavity, the latter being formed in conformity with the longitudinal sectional shape of a cap6ule and having at at least one longitudinal end a Fx~age CQY~LL~g for a t~ sversely (= in the lc~git1~inal direction of the capsule receiving cavity) reciprocating pieroing needle, and wherein the part of the devi oe cc~prising the mouth pie oe is m~l~rt3d to turn relative to the capsule re oe iving cavity comprising part of the devi oe ~etween a closed ready for use-position and an c~ 3d position permitting the inserticn of a r~EY~lle.
Such devices are allx~dy kT~h~n in vari~ em~xtlb=e~ts. A typical example of such a well-known devi oe is disclosed in Nl,A-176837 and NLrA-179345.
~ ith this well-known devi oe the nxlI~h piece co~prising part of the devi oe is rc~tatably nY~mted - abcut an ~YiS that is p~siticned exoentrically to its longitu~nal axLs - relative to the other part of the devi oe, whi~h comprises the nL~c~ng chamber, the ~npsule-re oe iving cavity and the piercing needle(5).
Ihe insertion of a capsule in the re oe iving cavity is rather difficult, because this is to take pla oe via the end of the mlx m g chamber facing the mouth pie oe. The remLval of an emptied capsule may also be difficult.
Another t~pical example of a w~ll-known devi oe of the type above referred to is disclosed in EF'~-0041783. With this well-kncwn devi oe the mauth piece is form mg a Exlrt ~hidh may be removed LL~II the rest of the devi oe , so that the devi oe may be loaded with a fresh capsule and an emptied capsule may be removed therefrom by taking the m~uth piece off. Morecver there are provisions wit~h this well-known device to jammungly hold a capsLle within the receiving cavity. For this purpose the walls of the caE~ e re oe iving cavity are pr~vided with ribs. The pierc mg of the ~ le is effected autcmatically when the 3S devi oe is closed by placing the mcuth pieoe, whereby the mouth piece actuates the piercing needle(s) and moreover - upon retraction of the piercing nee~le(s) - actuates an ejecting member. This means that whén WO 92/10230 PCI'/NL91/00259 ~r'`~. 2 -~ne device is closed upon placing a capsule, the latter will be au~
matically pierced and then, for direct use, ejected into the m~x~ng chamber. ~hus the closed position is also the use position. Conse-auently it is not possible to plaoe a ca~sule for later use i.e. to pos~pone piercing of the capsule until the n~nent at which the d~vice is actually used.
The invention aims at providing an i~proved devioe of the type under consideration.
In accor~nce with one aspect of t~e inverrtion an ir~alation 10 device of the type defined in tlle first part of claim 1 and disclosed in NIrA-176837 (vide also NIrA-179345) is pr~vided, which is characte-rized in that the mouth pieoe is integrally formed with the mixin~ -ch~er, whereas the capsule receiving cavity is provided in a bottam section which closes the m~x~r~ cham~er in the closed or ready for :-1~ u~position and is making part of aid other part of the device. As a ~ ~
result of this the a~qibility of the receiving cavity has been improved, so that a capsule can na~ be easily put into its seat. ~
Moreover cleaning has becane easier. ~ -In acoor~ce with a se~l asp3ct of the invention an ir~ala-20 tion devioe of the type defined in the first part of claim 2 anddisclosed in EP A-0041783 is pr~ided, which is characterized in that the mouth pieoe consists of two sections, one of which form~ part of one of the mavably connected body parts and the other of which being n~unted for a sliding movement relative to said first section between 25 between a ~etracted, inactive position and an extended active position, wherein the second mouth piece section is carrying the piercing needle(s) and the ejectir~ Dber, whereas the body part containing the capsule-receiving caVity is n~nted such that it can be moved into its closed position and fram the latter position in the 30 oper~ed position only when the ~th pieoe is taking its retracted position.
In this embcdiment, when the mouth piece is in its retracted position, it is possible to plaoe a capsule into the receiving cavity for later ll~P and then close the device without the capsule beirx~
35 pierced. The piercing will be effe~ted oally when the user actually wishes to use the device. For that purpose the us~ will have to extend the mouth piece so as to be able to take it into his mouth, thereby automatically ef~ecting the pi~rcing of the ca~lle and the ejection of the latter into the swirl chamber. Furthermore it can not ., , ., . ,. .. . ,, , . .. . .. ,,.. , ., ".. ~.. , .,. . ., ., , .. ,:.: .. , .. ., , . . ~ .
YVO 92/10230 PC~r/NL91/00259 3 2~?7~
occur that an inhalation at~empt is made with a non-pierced capsule within the swirl chamber, such as e.g. wit~ ~e device according to NLrA-176837.
In accordance with a further feature of the invention the two parts of (the bod,v of) the devi oe are conr~x~ted abcut an axis that is located in a center plane of the mGuth piece on that side of the mixing chamber that is turned away from the free Dx~lth piece end, and directed perpenlicul æ ly to the longitudinal axis of the mouth piece.
Due to this the devi oe of the invention has in principle Qbtained the character of an easily openable and closable box. The manner of using the inhalation devi oe of the invention has thus become more simple, and is now of a rather "naturzl" ch~Iracter.
The invention will be hereinafter further explained by way of example with reference to the drawing.
Fig. 1 is a perspective view of the inhalation devi oe accor~ing to the invention, in the opened position and with the mouth pie oe in its retracted position;
fig. 2 is a view as shown in fig. 1, b~t with the compcsing parts in a deas~3mbled state;
fig. 3 is a cross-sectional view of the devi oe in the closed pcsition, along the vertical midplane;
fig. 4 is a cross-section along the line IV-IV in fig. 3;
fig. 5 is a cross-section along the line V-V in fig. 3;
fig. 6 is a cross-sectional view of a detail; and fig. 7 is a front view on true scale of the inhalation device in its closed position.
The inhalation devi oe shown in the drawings comprises two parts A and B, which are pivctally conr~x~ted about an axis 1. These two parts may be closed in the aumow direction from the opened position shcwn in fig. 1 to form a relatively flat box.
The parts A and ~ each comprise a circular shell 2 and 3 respec-tively, containing a filling a and b respectively.
The two fillings a and b, which together constitute the proper inhalation devi oe , will be hereinafter further described with refe-ren oe to the further figures of the drawings.
The filling a is formed ~y a circular support plate 4, which is : ;
integrally formed with a m~unth piece section 6 and a substantially flat-cylindrical mlxing and swirl chamker 7 connecte~ with the latte~;
in the assembled position the suçport plate just fits within the . ': ' ' ' '''' .... ... : .. : :. . . . .. ~ ... . .. -. -.. -W O 92/10230 2 C~17r~ C ~ ~ P ~ /NL9l/00259 _ir~umferential edge of the shell 2.
The axis of the mouth piece section 6 and the ch~nber 7 connec-ted therewith coincides with a center line laying in t~he upper surfa oe of the support plate 4 and directed at ri~ht angles to the pivot axis 1, whereas the terminal edge 8 of the chamber 7 tu3l~ed away from the uFper portion of the mcuth piece section 6 is located in a plane wnlch p?ScPc ~hrcu3h the centre of the support plate and is direc~ed a~
right angles to sald center line.
,The termin21 edge 8 has a portion whic-h is located under the support plate 4 and is exten~ed tch~lrds the pivot axis 1 to form an arclate support means 8a (vide fig. 3) for a kx~m section which has still to be described and is me~c~ng part of the filling b of the part B.
A perforated partition 9 is provided between the mouth piece section 6 and the chamber 7. At two diametrically c~xx~sd locations o~
the circumferential wall of the chamber suk~antially tangentially directed air inlet passages 30 are provided, which coLL~a~und.with air inlet openings 31 pr~vided in the shells 2 and 3 (vide fig. S, 2 and 7).
Behind the chamber 7 the s~ ort plate 4 is ref~ised up to adjacent the circumferential edge of the plate, at 10. Guide ways 11 are extf~xling at right angles from the two lonyitud~mal edges of the rex~ss 10 and are adapte~ to receive block-shaped needle carriers 12 (vide fig. 2) and to guide these c~rriers in the transversal direction. The guide ways 11 are formed by upwardly directed ~ulgings of the su~port plate 4.
~ n the inner mcuth piece section 6 which is fixedly connected to the support plate 4, there is pravided an outer mcuth piece section 14, Which may slide on the mcuth pieCe section 6 between a retracted position (fig. 1 and 3) and an ex~nded or active pr~ition. For this purpose a slot 13 is c~t in the support plate 4 on both sides of the fixed mouth piece section 6, while the outer mouth piece section 14 is projecting with its lower portion through a corresponding recess 15 of thè shell 2. The outer mcuth piece section is provided with rearwardly extending lower and uç~er finger grip tonyues 32 and 33 respectively (fig. 3 and 5), which ahut - in the reLldcted'position of the mouth piece section 24 - against the cross edge of the recess 15 in the shell 2 and against the cross edge of a similar, still to be described recess in the shell 3 (fig. 3) respectively. In the ,, ,. ~, .. . . .. ... . . . .
W O 92/10230 PC~r/NL91/00259
The invention relates to a devi oe Por use with the inhalation of powdered materials contained in rod-s~ped capsules, of the type, cG~prising a mlx1ng chan~x~r havlng s~k~ ntially tangentially direx~ed air inlet cpenings, said mlx m g ch2mber having one end in ccmmunica-tion with a ~cuth piece and the ct~Er end in ccmmunication with ac ~ e receiving cavity, the latter being formed in conformity with the longitudinal sectional shape of a cap6ule and having at at least one longitudinal end a Fx~age CQY~LL~g for a t~ sversely (= in the lc~git1~inal direction of the capsule receiving cavity) reciprocating pieroing needle, and wherein the part of the devi oe cc~prising the mouth pie oe is m~l~rt3d to turn relative to the capsule re oe iving cavity comprising part of the devi oe ~etween a closed ready for use-position and an c~ 3d position permitting the inserticn of a r~EY~lle.
Such devices are allx~dy kT~h~n in vari~ em~xtlb=e~ts. A typical example of such a well-known devi oe is disclosed in Nl,A-176837 and NLrA-179345.
~ ith this well-known devi oe the nxlI~h piece co~prising part of the devi oe is rc~tatably nY~mted - abcut an ~YiS that is p~siticned exoentrically to its longitu~nal axLs - relative to the other part of the devi oe, whi~h comprises the nL~c~ng chamber, the ~npsule-re oe iving cavity and the piercing needle(5).
Ihe insertion of a capsule in the re oe iving cavity is rather difficult, because this is to take pla oe via the end of the mlx m g chamber facing the mouth pie oe. The remLval of an emptied capsule may also be difficult.
Another t~pical example of a w~ll-known devi oe of the type above referred to is disclosed in EF'~-0041783. With this well-kncwn devi oe the mauth piece is form mg a Exlrt ~hidh may be removed LL~II the rest of the devi oe , so that the devi oe may be loaded with a fresh capsule and an emptied capsule may be removed therefrom by taking the m~uth piece off. Morecver there are provisions wit~h this well-known device to jammungly hold a capsLle within the receiving cavity. For this purpose the walls of the caE~ e re oe iving cavity are pr~vided with ribs. The pierc mg of the ~ le is effected autcmatically when the 3S devi oe is closed by placing the mcuth pieoe, whereby the mouth piece actuates the piercing needle(s) and moreover - upon retraction of the piercing nee~le(s) - actuates an ejecting member. This means that whén WO 92/10230 PCI'/NL91/00259 ~r'`~. 2 -~ne device is closed upon placing a capsule, the latter will be au~
matically pierced and then, for direct use, ejected into the m~x~ng chamber. ~hus the closed position is also the use position. Conse-auently it is not possible to plaoe a ca~sule for later use i.e. to pos~pone piercing of the capsule until the n~nent at which the d~vice is actually used.
The invention aims at providing an i~proved devioe of the type under consideration.
In accor~nce with one aspect of t~e inverrtion an ir~alation 10 device of the type defined in tlle first part of claim 1 and disclosed in NIrA-176837 (vide also NIrA-179345) is pr~vided, which is characte-rized in that the mouth pieoe is integrally formed with the mixin~ -ch~er, whereas the capsule receiving cavity is provided in a bottam section which closes the m~x~r~ cham~er in the closed or ready for :-1~ u~position and is making part of aid other part of the device. As a ~ ~
result of this the a~qibility of the receiving cavity has been improved, so that a capsule can na~ be easily put into its seat. ~
Moreover cleaning has becane easier. ~ -In acoor~ce with a se~l asp3ct of the invention an ir~ala-20 tion devioe of the type defined in the first part of claim 2 anddisclosed in EP A-0041783 is pr~ided, which is characterized in that the mouth pieoe consists of two sections, one of which form~ part of one of the mavably connected body parts and the other of which being n~unted for a sliding movement relative to said first section between 25 between a ~etracted, inactive position and an extended active position, wherein the second mouth piece section is carrying the piercing needle(s) and the ejectir~ Dber, whereas the body part containing the capsule-receiving caVity is n~nted such that it can be moved into its closed position and fram the latter position in the 30 oper~ed position only when the ~th pieoe is taking its retracted position.
In this embcdiment, when the mouth piece is in its retracted position, it is possible to plaoe a capsule into the receiving cavity for later ll~P and then close the device without the capsule beirx~
35 pierced. The piercing will be effe~ted oally when the user actually wishes to use the device. For that purpose the us~ will have to extend the mouth piece so as to be able to take it into his mouth, thereby automatically ef~ecting the pi~rcing of the ca~lle and the ejection of the latter into the swirl chamber. Furthermore it can not ., , ., . ,. .. . ,, , . .. . .. ,,.. , ., ".. ~.. , .,. . ., ., , .. ,:.: .. , .. ., , . . ~ .
YVO 92/10230 PC~r/NL91/00259 3 2~?7~
occur that an inhalation at~empt is made with a non-pierced capsule within the swirl chamber, such as e.g. wit~ ~e device according to NLrA-176837.
In accordance with a further feature of the invention the two parts of (the bod,v of) the devi oe are conr~x~ted abcut an axis that is located in a center plane of the mGuth piece on that side of the mixing chamber that is turned away from the free Dx~lth piece end, and directed perpenlicul æ ly to the longitudinal axis of the mouth piece.
Due to this the devi oe of the invention has in principle Qbtained the character of an easily openable and closable box. The manner of using the inhalation devi oe of the invention has thus become more simple, and is now of a rather "naturzl" ch~Iracter.
The invention will be hereinafter further explained by way of example with reference to the drawing.
Fig. 1 is a perspective view of the inhalation devi oe accor~ing to the invention, in the opened position and with the mouth pie oe in its retracted position;
fig. 2 is a view as shown in fig. 1, b~t with the compcsing parts in a deas~3mbled state;
fig. 3 is a cross-sectional view of the devi oe in the closed pcsition, along the vertical midplane;
fig. 4 is a cross-section along the line IV-IV in fig. 3;
fig. 5 is a cross-section along the line V-V in fig. 3;
fig. 6 is a cross-sectional view of a detail; and fig. 7 is a front view on true scale of the inhalation device in its closed position.
The inhalation devi oe shown in the drawings comprises two parts A and B, which are pivctally conr~x~ted about an axis 1. These two parts may be closed in the aumow direction from the opened position shcwn in fig. 1 to form a relatively flat box.
The parts A and ~ each comprise a circular shell 2 and 3 respec-tively, containing a filling a and b respectively.
The two fillings a and b, which together constitute the proper inhalation devi oe , will be hereinafter further described with refe-ren oe to the further figures of the drawings.
The filling a is formed ~y a circular support plate 4, which is : ;
integrally formed with a m~unth piece section 6 and a substantially flat-cylindrical mlxing and swirl chamker 7 connecte~ with the latte~;
in the assembled position the suçport plate just fits within the . ': ' ' ' '''' .... ... : .. : :. . . . .. ~ ... . .. -. -.. -W O 92/10230 2 C~17r~ C ~ ~ P ~ /NL9l/00259 _ir~umferential edge of the shell 2.
The axis of the mouth piece section 6 and the ch~nber 7 connec-ted therewith coincides with a center line laying in t~he upper surfa oe of the support plate 4 and directed at ri~ht angles to the pivot axis 1, whereas the terminal edge 8 of the chamber 7 tu3l~ed away from the uFper portion of the mcuth piece section 6 is located in a plane wnlch p?ScPc ~hrcu3h the centre of the support plate and is direc~ed a~
right angles to sald center line.
,The termin21 edge 8 has a portion whic-h is located under the support plate 4 and is exten~ed tch~lrds the pivot axis 1 to form an arclate support means 8a (vide fig. 3) for a kx~m section which has still to be described and is me~c~ng part of the filling b of the part B.
A perforated partition 9 is provided between the mouth piece section 6 and the chamber 7. At two diametrically c~xx~sd locations o~
the circumferential wall of the chamber suk~antially tangentially directed air inlet passages 30 are provided, which coLL~a~und.with air inlet openings 31 pr~vided in the shells 2 and 3 (vide fig. S, 2 and 7).
Behind the chamber 7 the s~ ort plate 4 is ref~ised up to adjacent the circumferential edge of the plate, at 10. Guide ways 11 are extf~xling at right angles from the two lonyitud~mal edges of the rex~ss 10 and are adapte~ to receive block-shaped needle carriers 12 (vide fig. 2) and to guide these c~rriers in the transversal direction. The guide ways 11 are formed by upwardly directed ~ulgings of the su~port plate 4.
~ n the inner mcuth piece section 6 which is fixedly connected to the support plate 4, there is pravided an outer mcuth piece section 14, Which may slide on the mcuth pieCe section 6 between a retracted position (fig. 1 and 3) and an ex~nded or active pr~ition. For this purpose a slot 13 is c~t in the support plate 4 on both sides of the fixed mouth piece section 6, while the outer mouth piece section 14 is projecting with its lower portion through a corresponding recess 15 of thè shell 2. The outer mcuth piece section is provided with rearwardly extending lower and uç~er finger grip tonyues 32 and 33 respectively (fig. 3 and 5), which ahut - in the reLldcted'position of the mouth piece section 24 - against the cross edge of the recess 15 in the shell 2 and against the cross edge of a similar, still to be described recess in the shell 3 (fig. 3) respectively. In the ,, ,. ~, .. . . .. ... . . . .
W O 92/10230 PC~r/NL91/00259
2 ,~ 7 ~ ~
retracted position the o~ter termin21 edqes oî the Lnner and outer mcuth piece sections 6 and l4 are laying in a common plane within the outer cir~nference of the shell 2.
An ejecting tongue 16 is connected with the outer mouth piece section 14 (vide fig. 2) which is located within the rearward part of the recess lO (adjaoent the pivot axis l) of the support plate ~ when the mouth piece is in its retracted position and which will be moved thrcuqh the slot lO forwardly when the cuter ~cuth piece section is moved in~o its extended p~sition. Ihe ejecting tongue 16 is connected to the outer mouth piece section 14 b~ DE#~ns of a cc~3cting yoke 17 (vide fig. 2) that, in the assembled state of the device, is located under the support plate 4 and for this reason is provided slightly under the horizontal center plane of the mouth piece section 14. When formed of plastics material the connecting yoke 17 may resilientl~,~
bend relative to the mouth piece section 14 in a sufficient degree to enable it to be asse~bled with the support plate 4.
As shown in fig. 2, guide grooves l9 are provided in the upper surfaces of the legs 18 of the connecting yoke and guide pins 20 which proj0ct frcm the lower side of the needle carriers 20 are engaging into these qro3ves.
The filling b of the part B camprises a su~#~ntially circular support plate 5 which - in the assembled state - just fits within the circumferential edqe of the shell 3 and which is provided with a slot 22 that corresponds with the slot 21 in the sheil 2 to accx$~nodate the upper portion of the outer mouth pi~r~ section 14 that projects upwardly from the support plate 4 of the part A. me support plate 5 is also provided with a slot 23 that corr~çxonds with the slot lO in the support plate 4, and with rrr~ccpc 24 for acccmmodating the bulgings of the support plate 4 which constitute the guideways ll for the needle riers.
T~he support plate 5 is integrally formed with a bottc~ section 25 serving to close the rear side of the mLxlng chamber 7 in part A
when the devi oe is in its closed position. The bottam section 25 has an end fa oe that is turned away fram the pivot axis l and engages the terminz~ eadge 8 of the chamber 7. Ihis end fa oe is forming a par~ of a cylindrical surface about the pivot axis l. Furthermore - in the closed position of the devi oe - the bott~m section 25 is engaging the rearwardly e#t~\YlLn~ supporting portion 8a of the mixing and swirl c~unber 7. A cavity 26 is provided in said end fa oe of the bottcm .,.,' ' ' '' W O 92/l0230 PC~r/NL91/00259 75~ 6 ~
section 25, which cavi~y is shaped to conform to the longituoin21 section of a rcd-shaped capsule having rcunded ends. On the wall of ~he cavity 26 pressure points are for~ed by ribs 35 (fig. 3 and 4) which extend in the capsule-inserting direction and provide for a slightly jammlng seat for the capsule C in the cavity 26. The longitudinal axis of the cavity 26 extends diametrically relative ~o the bottcm section 25 and parallel to the pivot axis 1. In the closed position of the devi oe this longitudin21 axis coincides with the ccmmon axis of the piercing needles carried by the blocks 12 in the guideways ll. Passage cFeYLL~ys 27 for the pie m in~ nedles 28 are provided in the s~herical end walls of the cavity 26 and positioned on said longitudin21 axis. As seen in the re~u~ard direction the cavity 26 mrges into a passage slot 40 for the ejecting tongue 16 described hereinabove.
The device d OE ibed hereinabove is also ada ~ ed to contain a supply of capsules. For this purpose in principle all that space within the closed shells 2 and 3 is available, which has not yet been taken by the ~cuth piece sections, the nL~uLng ct2~ber, the bottcm section and the needle carriers. In those zones of the superinçxx~3d support plates 4 and 5 which are nat covered by the latter parts, recesses may be provided, the form of which corresponds with the longitudinal sectional shape of the capsules. A respective detail is shown in fig. 4, where a supply capsNle C' is received in a broad-dimensioned recess 36 of the support plate 4 and held jammed therein by ribs 37 projecting from the edges of said recess. The capsule is supported on a cross rib 38 provided on the inner side of the shell 2, which rib may - after the part B being opened - act as a tilting rib and thus facilitate the remcNal of the capsule (vide fig. 6).
The preferred inhalation devi oe shown in the drawings forms - in its closed and retracted position - a rather compact and flat article, the size of which hardly goes beyond that of a classic pocket watch or pcwder ccmpact, so that it may be put away in the user's clothing in a comfortable manner. m e actions to be performed for using the devi oe hardly require instructions. m e cQening of the "box" and the inser-tion of a ca~ e may be considered as natural actions and the sameapplies for the act of taking the finger grip tongues 32 and 33 between thumb and mdex figer to extend the mouth piece so as to take the latter into the usier's mouth.
When e~dln~d m g the mouth piece the cap~ e ends are automati-O 92/10230 P ~ /NL91/002592~?~
cally pierced. With reference to fig. 2 it will be understood ~nat substantially halfway of the extension m~vem2nt - when the guide pins 20 of the needle carriers 12 will be positioned in the inwardly directed curves of the guideways 19 - the needles 28 are c~mpletely irs~rted and that these needles will th~o~ tec - when the extension movement is continued - be retracted from the capsule ends. In the final phase of the extension movement, when the needles have already k~#~n retrac~ed from ~he cap6ule, the ejec~mg tcngue 16 will p?~
t~oxii~h the passage slot 40 in the kc~x3m saction 25 to eject the pierced capsule from the bottom section 25 into the nL~uLng chamber 7.
The rather flat shape facilitates the handling during inhaling, whereby the wall portions ebe~Ylling laterally from the extYYYIing mouth pi~ce constitute an abu~nt surface for the user' s lips and thus contribute to an optimal use.
lS For the rest the operation during inhalir~ corresponos to that of the -well~ n d vioe. Air from the =Irm~i~ atn~here is sucked thro~gh the tangential air inlet passages into the cha~er 7 and causes the capsule to b~ ara~d within the cha~er, whereby the pa~lered material is expelled from the ca~;ule ar~ is m~xed with the 20 air withLn the chamber 7, so that ~n air~er mixb~re is breathed in by the user.
me devic 3 described hereinab~ve may ~3e suitably formed of plastics material.
';'"' '.,:
' ~; ' :
.' "': .
::' .':
. .:
" ".
retracted position the o~ter termin21 edqes oî the Lnner and outer mcuth piece sections 6 and l4 are laying in a common plane within the outer cir~nference of the shell 2.
An ejecting tongue 16 is connected with the outer mouth piece section 14 (vide fig. 2) which is located within the rearward part of the recess lO (adjaoent the pivot axis l) of the support plate ~ when the mouth piece is in its retracted position and which will be moved thrcuqh the slot lO forwardly when the cuter ~cuth piece section is moved in~o its extended p~sition. Ihe ejecting tongue 16 is connected to the outer mouth piece section 14 b~ DE#~ns of a cc~3cting yoke 17 (vide fig. 2) that, in the assembled state of the device, is located under the support plate 4 and for this reason is provided slightly under the horizontal center plane of the mouth piece section 14. When formed of plastics material the connecting yoke 17 may resilientl~,~
bend relative to the mouth piece section 14 in a sufficient degree to enable it to be asse~bled with the support plate 4.
As shown in fig. 2, guide grooves l9 are provided in the upper surfaces of the legs 18 of the connecting yoke and guide pins 20 which proj0ct frcm the lower side of the needle carriers 20 are engaging into these qro3ves.
The filling b of the part B camprises a su~#~ntially circular support plate 5 which - in the assembled state - just fits within the circumferential edqe of the shell 3 and which is provided with a slot 22 that corresponds with the slot 21 in the sheil 2 to accx$~nodate the upper portion of the outer mouth pi~r~ section 14 that projects upwardly from the support plate 4 of the part A. me support plate 5 is also provided with a slot 23 that corr~çxonds with the slot lO in the support plate 4, and with rrr~ccpc 24 for acccmmodating the bulgings of the support plate 4 which constitute the guideways ll for the needle riers.
T~he support plate 5 is integrally formed with a bottc~ section 25 serving to close the rear side of the mLxlng chamber 7 in part A
when the devi oe is in its closed position. The bottam section 25 has an end fa oe that is turned away fram the pivot axis l and engages the terminz~ eadge 8 of the chamber 7. Ihis end fa oe is forming a par~ of a cylindrical surface about the pivot axis l. Furthermore - in the closed position of the devi oe - the bott~m section 25 is engaging the rearwardly e#t~\YlLn~ supporting portion 8a of the mixing and swirl c~unber 7. A cavity 26 is provided in said end fa oe of the bottcm .,.,' ' ' '' W O 92/l0230 PC~r/NL91/00259 75~ 6 ~
section 25, which cavi~y is shaped to conform to the longituoin21 section of a rcd-shaped capsule having rcunded ends. On the wall of ~he cavity 26 pressure points are for~ed by ribs 35 (fig. 3 and 4) which extend in the capsule-inserting direction and provide for a slightly jammlng seat for the capsule C in the cavity 26. The longitudinal axis of the cavity 26 extends diametrically relative ~o the bottcm section 25 and parallel to the pivot axis 1. In the closed position of the devi oe this longitudin21 axis coincides with the ccmmon axis of the piercing needles carried by the blocks 12 in the guideways ll. Passage cFeYLL~ys 27 for the pie m in~ nedles 28 are provided in the s~herical end walls of the cavity 26 and positioned on said longitudin21 axis. As seen in the re~u~ard direction the cavity 26 mrges into a passage slot 40 for the ejecting tongue 16 described hereinabove.
The device d OE ibed hereinabove is also ada ~ ed to contain a supply of capsules. For this purpose in principle all that space within the closed shells 2 and 3 is available, which has not yet been taken by the ~cuth piece sections, the nL~uLng ct2~ber, the bottcm section and the needle carriers. In those zones of the superinçxx~3d support plates 4 and 5 which are nat covered by the latter parts, recesses may be provided, the form of which corresponds with the longitudinal sectional shape of the capsules. A respective detail is shown in fig. 4, where a supply capsNle C' is received in a broad-dimensioned recess 36 of the support plate 4 and held jammed therein by ribs 37 projecting from the edges of said recess. The capsule is supported on a cross rib 38 provided on the inner side of the shell 2, which rib may - after the part B being opened - act as a tilting rib and thus facilitate the remcNal of the capsule (vide fig. 6).
The preferred inhalation devi oe shown in the drawings forms - in its closed and retracted position - a rather compact and flat article, the size of which hardly goes beyond that of a classic pocket watch or pcwder ccmpact, so that it may be put away in the user's clothing in a comfortable manner. m e actions to be performed for using the devi oe hardly require instructions. m e cQening of the "box" and the inser-tion of a ca~ e may be considered as natural actions and the sameapplies for the act of taking the finger grip tongues 32 and 33 between thumb and mdex figer to extend the mouth piece so as to take the latter into the usier's mouth.
When e~dln~d m g the mouth piece the cap~ e ends are automati-O 92/10230 P ~ /NL91/002592~?~
cally pierced. With reference to fig. 2 it will be understood ~nat substantially halfway of the extension m~vem2nt - when the guide pins 20 of the needle carriers 12 will be positioned in the inwardly directed curves of the guideways 19 - the needles 28 are c~mpletely irs~rted and that these needles will th~o~ tec - when the extension movement is continued - be retracted from the capsule ends. In the final phase of the extension movement, when the needles have already k~#~n retrac~ed from ~he cap6ule, the ejec~mg tcngue 16 will p?~
t~oxii~h the passage slot 40 in the kc~x3m saction 25 to eject the pierced capsule from the bottom section 25 into the nL~uLng chamber 7.
The rather flat shape facilitates the handling during inhaling, whereby the wall portions ebe~Ylling laterally from the extYYYIing mouth pi~ce constitute an abu~nt surface for the user' s lips and thus contribute to an optimal use.
lS For the rest the operation during inhalir~ corresponos to that of the -well~ n d vioe. Air from the =Irm~i~ atn~here is sucked thro~gh the tangential air inlet passages into the cha~er 7 and causes the capsule to b~ ara~d within the cha~er, whereby the pa~lered material is expelled from the ca~;ule ar~ is m~xed with the 20 air withLn the chamber 7, so that ~n air~er mixb~re is breathed in by the user.
me devic 3 described hereinab~ve may ~3e suitably formed of plastics material.
';'"' '.,:
' ~; ' :
.' "': .
::' .':
. .:
" ".
Claims (7)
1. A device for use with the inhalation of powdered materials contained in rod-shaped capsules of the type, comprising a mixing chamber having substantially tangentially directed air inlet openings, said mixing chamber having one end in communication with a mouth piece and the other end in communication with a capsule receiving cavity, the latter being formed in conformity with the longitudinal sectional shape of a capsule and having at at least one longitudinal end a passage opening for a transversally (= in the longitudinal direction of the capsule receiving cavity) reciprocating piercing needle, and wherein a part of the device that comprises the mouth piece is moun-ted to turn relative to a capsule receiving cavity comprising second part of the device between a closed ready for use-position and an opened position permitting the insertion of a capsule, characterized in that the mouth piece is integrally formed with the mixing chamber, whereas the capsule receiving cavity is provided in a bottom section which closes the mixing chamber in the closed or ready for use-position and is making part of said second part of the device.
2. A device for use with the inhalation of powdered materials contained in rod-shaped capsules, comprising a body with two parts mounted to be moved one relative to the other and provided with a mixing chamber having tangentially directed air inlet openings, said mixing chamber having one end in communication with a mouth piece and the other end in communication with a capsule receiving cavity, said cavity being formed in conformity with the longitudinal sectional shape of a capsule and being adapted to jammingly hold a capsule, at least one longitudinal end of said cavity having a passage opening for a transversally (= in the longitudinal direction of the capsule receiving cavity) reciprocating piercing needle, an ejecting member being provided which is mounted to be moved into the receiving cavity to urge a capsule from said cavity into the mixing chamber and wherein the mouth piece is mounted to be moved relative to the capsule receiving cavity comprising part between a closed position and an opened position permitting the insertion of a capsule and wherein the mouth piece is provided with means adapted to first actuate the piercing needle(s) and then the ejecting member when said mouth piece is moving into a use position, characterized in that the mouth piece consists of two sections, one of which forming part of one of the movably connected body parts and the other of which being mounted for a sliding movement relative to said first section between a retracted, inactive position and an extended active position, wherein the second mouth piece secton is carrying the piercing needle(s) and the ejecting member, whereas the body part contain m g the capsule-receiving cavity is mounted such that it can be moved into its closed position and from the latter position into the opened position only when the mouth piece is taking its retracted position.
3. A device according to claim 1 or 2, characterized in that the two parts of (the body of) the device are connected about a pivot axis that is located in a center plane of the mouth piece, substantially perpendicular to the longitudinal axis of the latter and positioned on that side of the mixing chamber that is turned away from the free mouth piece end.
4. A device according to claims 2 and 3, characterized in that the piercing needle is located in the the pivot axis containing center plane of the mouth piece and housed in that part of the device that comprises the stationary section of the mouth piece and the mixing chamber, whereas the slidable section of the mouth piece carries a U-shaped connecting piece having leg portions located on either side of the mixing chamber and a bridge portion that extends behind said bottom section and carries said ejecting member, the latter being tongue shaped,
5. A device according to claims 2-4, characterized in that the mouth piece and the mixing chamber are making part of a supporting plate laying substantially in a center plane of said mouth piece and mixing chamber, said support plate just fitting within the circum-ferential edge of a shell-shaped box portion, whereas the bottom section is making part of a second support plate laying substantially in a center plane of said bottom section and just fitting within the circumferential edge of a second shell-shaped box portion, that is connected with said first box portion via a id laterally positioned pivot axis, in such a way that the two support plates are resting one onto the other when the box is closed.
6. A device according to claim 5, characterized in that recesses are provided in said two shell portions, through which the mouth piece wall portions, which extend on both sides of said center plane, may project outwardly.
7. A device according to claims 5-6, characterized in that in those zones of the support plates which are located beyond said mouth piece and bottom sections, recesses are provided for receiving supply capsules.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9002706A NL9002706A (en) | 1990-12-10 | 1990-12-10 | Apparatus for use when inhaling powdered materials packaged in rod capsules. |
| NL9002706 | 1990-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2075501A1 true CA2075501A1 (en) | 1992-06-11 |
Family
ID=19858115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002075501A Abandoned CA2075501A1 (en) | 1990-12-10 | 1991-12-10 | Device for use with the inhalation of powdered materials contained in rod-shaped capsules |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5320095A (en) |
| EP (1) | EP0491426B1 (en) |
| JP (1) | JPH05504707A (en) |
| KR (1) | KR920703142A (en) |
| AT (1) | ATE151649T1 (en) |
| AU (1) | AU655792B2 (en) |
| CA (1) | CA2075501A1 (en) |
| DE (1) | DE69125695T2 (en) |
| DK (1) | DK0491426T3 (en) |
| ES (1) | ES2102993T3 (en) |
| FI (1) | FI923551A (en) |
| GR (1) | GR3023168T3 (en) |
| NL (1) | NL9002706A (en) |
| NO (1) | NO302930B1 (en) |
| WO (1) | WO1992010230A1 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY105368A (en) | 1990-03-02 | 1994-09-30 | Glaxo Group Ltd | Inhalation device. |
| SK280967B6 (en) * | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Inhalation device |
| BR9106690A (en) * | 1991-04-15 | 1993-06-29 | Huhtamaeki Yhthymae Oy | PROVISION TO MEASURE A DOSE OF PULVERULENT DRUGS FOR INHALATION AND INHALATION APPARATUS EQUIPPED WITH THE SAME |
| AUPM411494A0 (en) * | 1994-02-25 | 1994-03-24 | Central Sydney Area Health Service | Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum |
| US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| US5669378A (en) * | 1995-12-21 | 1997-09-23 | Pera; Ivo | Inhaling device |
| SE9801114D0 (en) * | 1998-03-30 | 1998-03-30 | Astra Ab | Inhalation device |
| DE19942080A1 (en) * | 1999-09-03 | 2001-03-08 | Inamed Gmbh | Inhaler |
| SE517229C2 (en) * | 2000-09-25 | 2002-05-14 | Microdrug Ag | Continuous dry powder inhaler |
| WO2002092154A1 (en) | 2001-04-26 | 2002-11-21 | New England Pharmaceuticals, Inc. | Metered dose delivery device for liquid and powder agents |
| GR1004350B (en) | 2002-03-29 | 2003-09-26 | Inhaler for dry powder | |
| EP1615689B1 (en) * | 2003-04-09 | 2016-02-03 | Novartis AG | Aerosolization apparatus with capsule puncture alignment guide |
| GB0317374D0 (en) | 2003-07-24 | 2003-08-27 | Glaxo Group Ltd | Medicament dispenser |
| GB0418278D0 (en) | 2004-08-16 | 2004-09-15 | Glaxo Group Ltd | Medicament dispenser |
| MX2007005522A (en) † | 2004-11-10 | 2007-07-05 | Cipla Ltd | Inhaler. |
| GB0507711D0 (en) | 2005-04-15 | 2005-05-25 | Vectura Group Plc | Improved blister piercing |
| GB0515584D0 (en) * | 2005-07-28 | 2005-09-07 | Glaxo Group Ltd | Medicament dispenser |
| DE102006010089A1 (en) * | 2006-02-24 | 2007-10-18 | Aha-Kunststofftechnik Gmbh | The dry powder inhaler |
| GB0622827D0 (en) * | 2006-11-15 | 2006-12-27 | Glaxo Group Ltd | Sheet driver for use in a drug dispenser |
| DE102007040366A1 (en) | 2007-08-17 | 2009-02-19 | Aha Kunststofftechnik Gmbh | The dry powder inhaler |
| US20090211576A1 (en) * | 2007-10-02 | 2009-08-27 | Timo Lehtonen | Safety and abuse deterrent improved device |
| ES2394589T3 (en) | 2007-12-14 | 2013-02-04 | Aerodesigns, Inc | Supply of food products transformable in aerosol |
| TR200803525A2 (en) * | 2008-05-16 | 2009-12-21 | Bi̇lgi̇ç Mahmut | Powder inhaler. |
| GB0901520D0 (en) * | 2009-01-30 | 2009-03-11 | Vectura Delivery Devices Ltd | Inhaler |
| WO2013016784A1 (en) | 2011-08-04 | 2013-02-07 | Victor Esteve | Dry powder inhaler |
| GB201301192D0 (en) | 2013-01-23 | 2013-03-06 | Vectura Delivery Devices Ltd | A blister piercing element for a dry powder inhaler |
| RU2629241C2 (en) | 2013-07-16 | 2017-08-28 | Эмпасиш Импортадора Эшпортадора И Дистрибуидора Ди Эмбалахенс Лтда | Powder inhaler |
| PL2944205T3 (en) * | 2014-05-15 | 2019-10-31 | Fontem Holdings 1 Bv | Electronic smoking device and mouthpiece |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2517482A (en) * | 1949-04-09 | 1950-08-01 | Sharp & Dohme Inc | Inhaler |
| DE2346914C3 (en) * | 1973-09-18 | 1980-10-16 | Paul Ritzau Pari-Werk, Gmbh & Co, 8130 Starnberg | Powdered substance inhaler |
| IT1016489B (en) * | 1974-03-18 | 1977-05-30 | Isf Spa | INHALER |
| GB1562732A (en) * | 1976-02-10 | 1980-03-12 | Allen & Hanburys Ltd | Device for dispensing medicaments |
| EP0005585B1 (en) * | 1978-05-03 | 1981-08-12 | FISONS plc | Inhalation device |
| GB2061735B (en) * | 1979-10-30 | 1983-11-30 | Riker Laboratories Inc | Breath actuated device for administration of powdered medicaments by inhalation |
| DE3167567D1 (en) * | 1980-06-06 | 1985-01-17 | Fisons Plc | Inhalation device for powdered medicaments |
| FI79651C (en) * | 1982-10-08 | 1990-02-12 | Glaxo Group Ltd | Dosing device for medicine |
| GR861995B (en) * | 1985-07-30 | 1986-11-04 | Glaxo Group Ltd | Devices for administering medicaments to patients |
| IT1222509B (en) * | 1987-08-17 | 1990-09-05 | Miat Spa | INSUFFLATOR FOR THE ADMINISTRATION OF DRUGS IN THE FORM OF PRE-DOSED POWDER IN OPERATIONS |
| GB8804069D0 (en) * | 1988-02-22 | 1988-03-23 | Britains Petite Ltd | Dispensers for powdered medication |
-
1990
- 1990-12-10 NL NL9002706A patent/NL9002706A/en not_active Application Discontinuation
-
1991
- 1991-12-10 DE DE69125695T patent/DE69125695T2/en not_active Expired - Fee Related
- 1991-12-10 EP EP91203235A patent/EP0491426B1/en not_active Expired - Lifetime
- 1991-12-10 KR KR1019920701919A patent/KR920703142A/en active IP Right Grant
- 1991-12-10 JP JP4501482A patent/JPH05504707A/en active Pending
- 1991-12-10 US US07/924,020 patent/US5320095A/en not_active Expired - Fee Related
- 1991-12-10 AT AT91203235T patent/ATE151649T1/en not_active IP Right Cessation
- 1991-12-10 WO PCT/NL1991/000259 patent/WO1992010230A1/en active Application Filing
- 1991-12-10 DK DK91203235.6T patent/DK0491426T3/en active
- 1991-12-10 CA CA002075501A patent/CA2075501A1/en not_active Abandoned
- 1991-12-10 ES ES91203235T patent/ES2102993T3/en not_active Expired - Lifetime
- 1991-12-10 AU AU91112/91A patent/AU655792B2/en not_active Ceased
-
1992
- 1992-08-07 FI FI923551A patent/FI923551A/en not_active Application Discontinuation
- 1992-08-07 NO NO923106A patent/NO302930B1/en unknown
-
1997
- 1997-04-17 GR GR970400795T patent/GR3023168T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL9002706A (en) | 1992-07-01 |
| GR3023168T3 (en) | 1997-07-30 |
| EP0491426B1 (en) | 1997-04-16 |
| NO923106D0 (en) | 1992-08-07 |
| ES2102993T3 (en) | 1997-08-16 |
| WO1992010230A1 (en) | 1992-06-25 |
| US5320095A (en) | 1994-06-14 |
| DE69125695T2 (en) | 1997-11-13 |
| AU655792B2 (en) | 1995-01-12 |
| DE69125695D1 (en) | 1997-05-22 |
| EP0491426A1 (en) | 1992-06-24 |
| FI923551A0 (en) | 1992-08-07 |
| JPH05504707A (en) | 1993-07-22 |
| AU9111291A (en) | 1992-07-08 |
| KR920703142A (en) | 1992-12-17 |
| ATE151649T1 (en) | 1997-05-15 |
| NO302930B1 (en) | 1998-05-11 |
| NO923106L (en) | 1992-10-07 |
| DK0491426T3 (en) | 1997-10-27 |
| FI923551A (en) | 1992-08-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2075501A1 (en) | Device for use with the inhalation of powdered materials contained in rod-shaped capsules | |
| CA1054479A (en) | Inhalation device | |
| FI72878C (en) | AEROSOLINHALERINGSANORDNING. | |
| IE841281L (en) | Medical administration device. | |
| US20010032644A1 (en) | Inhalation device | |
| NZ234963A (en) | Mouth inhaler: revolving magazine of encapsulated drugs | |
| JPH0257942B2 (en) | ||
| CZ282478B6 (en) | Inhaler | |
| KR20130140070A (en) | Inhalator | |
| CA2104290A1 (en) | Inhaler | |
| EP0619746B1 (en) | Synchronization device for aerosol appliances with pressurized regulating bottle | |
| CA2019385A1 (en) | Disposable medicament inhalation device | |
| JPS6340546A (en) | Preparatory preparation device of photocurable material | |
| US4577753A (en) | Sealed message carrier | |
| IE53412B1 (en) | Medical aerosol dispensing device | |
| EP2968072B1 (en) | Child resistant cover for oral dosage forms | |
| DK0806214T3 (en) | inhaler | |
| CN217038873U (en) | Bead pushing device | |
| TWI728586B (en) | Arrangement for supporting medicament delivery devices and system | |
| KR870001101Y1 (en) | Mixing case for various portable | |
| CN114145491A (en) | Cigarette holder cigarette bead filter | |
| JPH0623600U (en) | Dispensing dispenser toy | |
| GB9013978D0 (en) | Medicament container and inhalation device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |