CA2069202C - The use of 1-(5-oxohexyl)-3-methyl-7-n-propylxanthine in vascular surgery - Google Patents

The use of 1-(5-oxohexyl)-3-methyl-7-n-propylxanthine in vascular surgery Download PDF

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Publication number
CA2069202C
CA2069202C CA002069202A CA2069202A CA2069202C CA 2069202 C CA2069202 C CA 2069202C CA 002069202 A CA002069202 A CA 002069202A CA 2069202 A CA2069202 A CA 2069202A CA 2069202 C CA2069202 C CA 2069202C
Authority
CA
Canada
Prior art keywords
propylxanthine
methyl
oxohexyl
interruption
blood circulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002069202A
Other languages
English (en)
French (fr)
Other versions
CA2069202A1 (en
Inventor
Viera Danielisova
Ralf Kolvenbach
Hans-Peter Schubert
John Grome
Ernst Jurgen Schneider
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Publication of CA2069202A1 publication Critical patent/CA2069202A1/en
Application granted granted Critical
Publication of CA2069202C publication Critical patent/CA2069202C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
CA002069202A 1991-05-23 1992-05-22 The use of 1-(5-oxohexyl)-3-methyl-7-n-propylxanthine in vascular surgery Expired - Lifetime CA2069202C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4116799 1991-05-23
DEP4116799.6 1991-05-23

Publications (2)

Publication Number Publication Date
CA2069202A1 CA2069202A1 (en) 1992-11-24
CA2069202C true CA2069202C (en) 2003-12-09

Family

ID=6432229

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002069202A Expired - Lifetime CA2069202C (en) 1991-05-23 1992-05-22 The use of 1-(5-oxohexyl)-3-methyl-7-n-propylxanthine in vascular surgery

Country Status (16)

Country Link
US (1) US5475002A (zh)
EP (1) EP0514789B1 (zh)
JP (1) JP3193767B2 (zh)
KR (1) KR100219011B1 (zh)
AT (1) ATE142498T1 (zh)
AU (1) AU651205B2 (zh)
CA (1) CA2069202C (zh)
DE (1) DE59207086D1 (zh)
DK (1) DK0514789T3 (zh)
ES (1) ES2093138T3 (zh)
GR (1) GR3021039T3 (zh)
HU (1) HU207798B (zh)
IE (1) IE75890B1 (zh)
IL (1) IL101953A (zh)
TW (1) TW207497B (zh)
ZA (1) ZA923747B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992021344A2 (en) * 1991-05-24 1992-12-10 Fred Hutchinson Cancer Research Center Modulation of cellular response to external stimuli
US5981536A (en) * 1996-07-31 1999-11-09 Hoechst Aktiengesellschaft Use of xanthine derivatives for the modulation of apoptosis
US5856330A (en) * 1996-07-31 1999-01-05 Hoechst Aktiengesellschaft Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin
US6413976B1 (en) 1999-04-06 2002-07-02 Trustees Of Dartmouth College Compositions and method for decreasing neuropathic pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2330742C2 (de) * 1973-06-16 1982-07-29 Hoechst Ag, 6000 Frankfurt 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
JPH062675B2 (ja) * 1985-04-05 1994-01-12 ヘキストジヤパン株式会社 記憶障害治療剤

Also Published As

Publication number Publication date
US5475002A (en) 1995-12-12
AU1706392A (en) 1992-11-26
ES2093138T3 (es) 1996-12-16
ATE142498T1 (de) 1996-09-15
HUT61469A (en) 1993-01-28
IE921658A1 (en) 1992-12-02
TW207497B (zh) 1993-06-11
HU9201695D0 (en) 1992-08-28
IE75890B1 (en) 1997-09-24
KR100219011B1 (ko) 1999-09-01
JP3193767B2 (ja) 2001-07-30
IL101953A (en) 1995-07-31
EP0514789B1 (de) 1996-09-11
JPH05139976A (ja) 1993-06-08
GR3021039T3 (en) 1996-12-31
AU651205B2 (en) 1994-07-14
EP0514789A1 (de) 1992-11-25
DK0514789T3 (zh) 1997-02-17
DE59207086D1 (de) 1996-10-17
IL101953A0 (en) 1992-12-30
CA2069202A1 (en) 1992-11-24
HU207798B (en) 1993-06-28
ZA923747B (en) 1992-12-30

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