CA2064705A1 - Methode de culture de hcv dans des cellules eucaryotiques - Google Patents

Methode de culture de hcv dans des cellules eucaryotiques

Info

Publication number
CA2064705A1
CA2064705A1 CA2064705A CA2064705A CA2064705A1 CA 2064705 A1 CA2064705 A1 CA 2064705A1 CA 2064705 A CA2064705 A CA 2064705A CA 2064705 A CA2064705 A CA 2064705A CA 2064705 A1 CA2064705 A1 CA 2064705A1
Authority
CA
Canada
Prior art keywords
methods
eukaryotic cells
culturing hcv
hcv
culturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2064705A
Other languages
English (en)
Other versions
CA2064705C (fr
Inventor
Amy J. Weiner
Kathelyn S. Steimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Vaccines and Diagnostics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23576300&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2064705(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Publication of CA2064705A1 publication Critical patent/CA2064705A1/fr
Application granted granted Critical
Publication of CA2064705C publication Critical patent/CA2064705C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24221—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Cellules pouvant être utilisées afin de propager le virus de l'hépatite C en culture. L'invention concerne également des antigènes viraux produits à l'aide desdites cultures, ainsi que l'emploi desdits antigènes, par exemple, dans des diagnostics.
CA002064705A 1989-08-25 1990-08-22 Methode de culture de hcv dans des cellules eucaryotiques Expired - Lifetime CA2064705C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39866789A 1989-08-25 1989-08-25
US398,667 1989-08-25

Publications (2)

Publication Number Publication Date
CA2064705A1 true CA2064705A1 (fr) 1991-02-26
CA2064705C CA2064705C (fr) 1999-04-06

Family

ID=23576300

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002064705A Expired - Lifetime CA2064705C (fr) 1989-08-25 1990-08-22 Methode de culture de hcv dans des cellules eucaryotiques

Country Status (12)

Country Link
EP (1) EP0414475B1 (fr)
JP (3) JPH05502156A (fr)
AT (1) ATE161041T1 (fr)
AU (1) AU655156B2 (fr)
CA (1) CA2064705C (fr)
DE (1) DE69031791T2 (fr)
DK (1) DK0414475T3 (fr)
ES (1) ES2110411T3 (fr)
GR (1) GR3026114T3 (fr)
IE (1) IE903097A1 (fr)
PT (1) PT95093B (fr)
WO (1) WO1991002820A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU87861A1 (fr) 1989-12-18 1991-10-08 Wellcome Found Agent viral
US7166287B1 (en) 1989-12-18 2007-01-23 Glaxo Wellcome Inc. Viral agent
EP0527786A1 (fr) * 1990-04-03 1993-02-24 Southwest Foundation For Biomedical Research Virus purifies de l'hepatite c et proteines et peptides de ces virus
AU7679491A (en) * 1990-04-04 1991-10-30 Protos, Inc. Hepatitis c virus protease inhibitors
EP0527815B1 (fr) * 1990-04-06 2000-07-19 Genelabs Technologies, Inc. Epitopes du virus de l'hepatite c
US5747339A (en) 1990-06-25 1998-05-05 Research Foundation For Microbial Diseases Of Osaka Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
CA2065690A1 (fr) * 1991-04-10 1992-10-11 Hiroaki Okamoto Antigenes lies a l'hepatite non-a, non-b, systemes de detection, polynucleotides et polypeptides
US5428145A (en) * 1991-08-09 1995-06-27 Immuno Japan, Inc. Non-A, non-B, hepatitis virus genome, polynucleotides, polypeptides, antigen, antibody and detection systems
AU671967B2 (en) * 1991-11-21 1996-09-19 Common Services Agency Hepatitis-C virus testing
US5552310A (en) * 1992-06-12 1996-09-03 Hiroshi Yoshikura Replication of hepatitis C virus genome and identification of virus having high infectivity
WO1994025064A1 (fr) * 1993-05-04 1994-11-10 THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMANSERVIC ES Propagation de cellules virales de l'hepatite c et procedes associes
US5840565A (en) 1995-08-22 1998-11-24 The Regents Of The University Of California Methods for enhancing the production of viral vaccines in PKR-deficient cell culture
US6127116A (en) 1995-08-29 2000-10-03 Washington University Functional DNA clone for hepatitis C virus (HCV) and uses thereof
US5851758A (en) * 1995-10-25 1998-12-22 Childrens Research Institute Cytopathic replication of hepatitis C virus in a new cell line
US6242187B1 (en) 1996-01-29 2001-06-05 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
AU732255B2 (en) * 1996-01-29 2001-04-12 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
WO1998021338A1 (fr) 1996-11-08 1998-05-22 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Synthese et purification de particules de type virus de l'hepatite c
US7049428B1 (en) 1998-03-04 2006-05-23 Washington University HCV variants
US7338759B1 (en) 1997-03-04 2008-03-04 Washington University HCV variants
AT407256B (de) * 1998-06-24 2001-02-26 Immuno Ag Hepatitis c-virus positive endometriale zelllinie
ES2296803T3 (es) 2000-08-17 2008-05-01 Tripep Ab Vacunas que contienen ribavirina.
RU2286172C2 (ru) 2000-08-17 2006-10-27 Трипеп Аб Вакцины, содержащие рибавирин, и способы их использования
US7022830B2 (en) 2000-08-17 2006-04-04 Tripep Ab Hepatitis C virus codon optimized non-structural NS3/4A fusion gene
US6680059B2 (en) 2000-08-29 2004-01-20 Tripep Ab Vaccines containing ribavirin and methods of use thereof
WO2007031867A2 (fr) 2005-05-25 2007-03-22 Tripep Ab Gene de fusion ns3/4a non structurel de l'hepatite c
EP2185195A2 (fr) 2007-08-16 2010-05-19 Tripep Ab Plate-forme immunogène
WO2009130588A2 (fr) 2008-04-22 2009-10-29 Tripep Ab Plateforme immunogène
GB201119011D0 (en) * 2011-11-03 2011-12-14 Queen Mary Innovation Ltd Method

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464474A (en) * 1980-07-09 1984-08-07 Connaught Laboratories Limited Non-A, non-B hepatitis assay and vaccine
WO1982002774A1 (fr) * 1981-02-11 1982-08-19 Baxter Travenol Lab Virus de l'hepatite non a et non b
JPS63502962A (ja) * 1986-04-01 1988-11-02 ジーンラブズ　インコーポレイテッド ウイルス特異的な永久増殖性組織細胞
IE62868B1 (en) * 1987-11-18 1995-03-08 Chiron Corp Hepatitis C virus

Also Published As

Publication number Publication date
DE69031791T2 (de) 1998-04-02
ES2110411T3 (es) 1998-02-16
PT95093B (pt) 1997-11-28
JP2001314192A (ja) 2001-11-13
WO1991002820A1 (fr) 1991-03-07
ATE161041T1 (de) 1997-12-15
CA2064705C (fr) 1999-04-06
AU6344990A (en) 1991-04-03
AU655156B2 (en) 1994-12-08
DE69031791D1 (de) 1998-01-22
GR3026114T3 (en) 1998-05-29
JP2004049235A (ja) 2004-02-19
EP0414475A1 (fr) 1991-02-27
DK0414475T3 (da) 1998-02-09
PT95093A (pt) 1991-05-22
IE903097A1 (en) 1991-02-27
EP0414475B1 (fr) 1997-12-10
JPH05502156A (ja) 1993-04-22

Similar Documents

Publication Publication Date Title
CA2064705A1 (fr) Methode de culture de hcv dans des cellules eucaryotiques
CA2039315A1 (fr) Cellule souche hematopoietique humaine
CA2045175A1 (fr) Production de proteines au moyen de la recombinaison homologue
AU4493993A (en) Culture vessel for cell cultures
CA2188165A1 (fr) Methode de multiplication et differenciation des cellules b et leur utilisation
DE69333855D1 (de) Aus einer mit einem Stamm von Multiple-Sklerosis-Virus infizierten Zellinie hergestelltes biologisches Virusmaterial
AU4493893A (en) Culture vessel for cell cultures
ES8106552A1 (es) Un procedimiento para la propagacion del virus de la hepati-tis a humana
AU2002361797A1 (en) Cell lines with latent immunodeficiency virus and methods of use thereof
ZA917561B (en) Media for culture of mammalian cells
AU8217387A (en) Process and device for the cultivation of immobilized or adherent mammalian cells, and the use thereof in the preparation of proteins
EP0292995A3 (fr) Appareil pour le transfert de cellules
EP0204522A3 (fr) Série d'anticorps monoclonaux pour la caractérisation de la compatibilité histologique
EP0156645A3 (en) Process for the preparation of n1-methyl-10alpha-methoxylumilysergol and esters thereof, and intermediates for their preparation
AU2190288A (en) Vector for the expression of proteins of the HIV-2 virus, one of the casual agents of AIDS, cell culture infected or transformed by this vector, proteins obtained, vaccine and antibodies obtained
DK0485504T3 (da) Fremgangsmåde til fremstilling af aktiveret protein C ved celledyrkning
JPS5774093A (en) Method of increasing interferon production
CA2222718A1 (fr) Cellules 293 presentant une faculte de fixation amelioree
AU6262786A (en) Growing aids virus in cell lines lacking human class ii histocompatability antigens
JPS5534017A (en) Preparation of itaconic acid
JPS5571491A (en) Preparation of proline acylase
DK204586D0 (da) Hybridceller, der producerer et karakteristisk antigen for hepatitis b-virus, opnaaet ud fra hepatocytter og celler, der er tilvejebragt fra aber, fremgangsmaade til opnaaelse af hybridcellerne og anvendelse af disse til produktion af antigenet
CA2058785A1 (fr) Methode pour l'obtention de proteines avec des derives fviii et ou a activite fviii
JPS5542527A (en) Culturing of acid-fast bacteria
Colombo et al. Methods Used and Results Obtained at the Joint Research Centre--Ispra for the Determination of Oxygen in Some Common Non-Ferrous Metals by Vacuum and Inert-Gas Fusion Techniques

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry