CA2058630A1 - Anticorps monoclonaux humains pour vih- 1 mn gp 120 - Google Patents
Anticorps monoclonaux humains pour vih- 1 mn gp 120Info
- Publication number
- CA2058630A1 CA2058630A1 CA002058630A CA2058630A CA2058630A1 CA 2058630 A1 CA2058630 A1 CA 2058630A1 CA 002058630 A CA002058630 A CA 002058630A CA 2058630 A CA2058630 A CA 2058630A CA 2058630 A1 CA2058630 A1 CA 2058630A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- amino acid
- hiv
- sequence
- envelope protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24141—Use of virus, viral particle or viral elements as a vector
- C12N2710/24143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36154189A | 1989-06-05 | 1989-06-05 | |
| US361,541 | 1989-06-05 | ||
| US43128189A | 1989-11-03 | 1989-11-03 | |
| US431,281 | 1989-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2058630A1 true CA2058630A1 (fr) | 1990-12-06 |
Family
ID=27001330
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002058630A Abandoned CA2058630A1 (fr) | 1989-06-05 | 1990-06-05 | Anticorps monoclonaux humains pour vih- 1 mn gp 120 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0478689A4 (fr) |
| JP (1) | JPH05506561A (fr) |
| AU (1) | AU6036690A (fr) |
| CA (1) | CA2058630A1 (fr) |
| IL (1) | IL94624A0 (fr) |
| PT (1) | PT94276A (fr) |
| WO (1) | WO1990015078A1 (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5712373A (en) * | 1990-07-02 | 1998-01-27 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | HIV monoclonal antibody specific for the HTLV-IIImn gp120 envelope glycoprotein |
| JP2989862B2 (ja) * | 1990-07-02 | 1999-12-13 | 財団法人化学及血清療法研究所 | モノクローナル抗体 |
| AU9072991A (en) * | 1990-10-26 | 1992-05-26 | Public Health Research Institute Of The City Of New York, Inc., The | Neutralizing human monoclonal antibodies specific for the v3 loop and cd-4 binding site of hiv-1 gp120 |
| IT1244529B (it) * | 1991-01-30 | 1994-07-15 | Ist Superiore Sanita | Peptidi sintetici atti a potenziare l'infettivita' del virus hiv-1 |
| WO1994004574A1 (fr) * | 1991-08-22 | 1994-03-03 | Nissin Shokuhin Kabushiki Kaisha | Immunotherapie du vih |
| WO1993004090A1 (fr) * | 1991-08-22 | 1993-03-04 | Nissin Shokuhin Kabushiki Kaisha | Immunotherapie du vih |
| HUT70461A (en) * | 1992-04-01 | 1995-10-30 | Merck Anc Co Inc | Recombinant human hiv-neutralizing monoclonal antibodies for prevention and treatment of hiv invention |
| PT728015E (pt) | 1992-06-18 | 2006-07-31 | Creagen Inc | Antigenes polipeptidicos combinatoriais |
| EP0588750A3 (fr) * | 1992-08-05 | 1995-01-11 | Cigb | Procédé pour la production de polypeptides recombinants contenant des épitopes dérivées d'isolées d'HIV différentes, leur utilisations comme immunigènes et pour la détection d'anticorps contre le HIV. |
| US6114143A (en) * | 1993-03-11 | 2000-09-05 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Anti-HIV monoclonal antibody |
| US5618922A (en) * | 1994-07-25 | 1997-04-08 | Nissin Shokuhin Kabushiki Kaisha | NM03 antibody materials and methods |
| US8332159B2 (en) | 2003-02-20 | 2012-12-11 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Method for enhancing efficacy of preparation of monoclonal antibody |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4755457A (en) * | 1985-02-05 | 1988-07-05 | Robert Guroff Marjorie | Method for detecting HTLV-III neutralizing antibodies in sera |
| ATE122237T1 (de) * | 1987-05-29 | 1995-05-15 | Tanox Biosystems Inc | Hiv-1 neutralisierende monoklonale antikörper. |
| EP0339504A3 (fr) * | 1988-04-26 | 1990-09-12 | The Du Pont Merck Pharmaceutical Company | Virus d'immunodéficience humaine (HIV) peptide env-codé capable de provoquer les anticorps inhibiteurs du HIV dans les mammifères |
| JPH04502760A (ja) * | 1988-10-03 | 1992-05-21 | レプリゲン・コーポレーション | エイズの診断，予防および治療に有効な新規ｈｉｖ蛋白質およびペプチド |
| WO1991006575A1 (fr) * | 1989-11-03 | 1991-05-16 | Repligen Corporation | Anticorps monoclonal humain specifique du vih-1 |
-
1990
- 1990-06-05 CA CA002058630A patent/CA2058630A1/fr not_active Abandoned
- 1990-06-05 IL IL94624A patent/IL94624A0/xx unknown
- 1990-06-05 JP JP90510360A patent/JPH05506561A/ja active Pending
- 1990-06-05 PT PT199094276A patent/PT94276A/pt not_active Application Discontinuation
- 1990-06-05 EP EP19900910991 patent/EP0478689A4/en not_active Withdrawn
- 1990-06-05 AU AU60366/90A patent/AU6036690A/en not_active Abandoned
- 1990-06-05 WO PCT/US1990/003157 patent/WO1990015078A1/fr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL94624A0 (en) | 1991-04-15 |
| PT94276A (pt) | 1991-02-08 |
| EP0478689A4 (en) | 1993-06-16 |
| EP0478689A1 (fr) | 1992-04-08 |
| WO1990015078A1 (fr) | 1990-12-13 |
| JPH05506561A (ja) | 1993-09-30 |
| AU6036690A (en) | 1991-01-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |