CA2054798A1 - Hcv-specific peptides, agents therefor and the use thereof - Google Patents

Hcv-specific peptides, agents therefor and the use thereof

Info

Publication number
CA2054798A1
CA2054798A1 CA002054798A CA2054798A CA2054798A1 CA 2054798 A1 CA2054798 A1 CA 2054798A1 CA 002054798 A CA002054798 A CA 002054798A CA 2054798 A CA2054798 A CA 2054798A CA 2054798 A1 CA2054798 A1 CA 2054798A1
Authority
CA
Canada
Prior art keywords
hcv
specific peptides
agents therefor
relates
immunochemical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002054798A
Other languages
French (fr)
Other versions
CA2054798C (en
Inventor
Udo Krupka
Werner Stuber
Manfred Gerken
Stefan Brust
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27435056&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2054798(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE4034982A external-priority patent/DE4034982C2/en
Priority claimed from DE4112743A external-priority patent/DE4112743C2/en
Priority claimed from DE4120281A external-priority patent/DE4120281C2/en
Priority claimed from DE4121431A external-priority patent/DE4121431A1/en
Application filed by Individual filed Critical Individual
Publication of CA2054798A1 publication Critical patent/CA2054798A1/en
Application granted granted Critical
Publication of CA2054798C publication Critical patent/CA2054798C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081—Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109—Hepatitis C virus; Hepatitis G virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to polypeptides for the immunochemical determination of HCV-specific antibodies and HCV antigens, and to agents suitable for this method and the use thereof. The invention also relates to an immunochemical method for the simultaneous detection and/or for the simultaneous determination of a plurality of, different antibody specificities against pathogens which are different in each case in a single test.
CA002054798A 1990-11-03 1991-11-01 Hcv-specific peptides, agents therefor and the use thereof Expired - Lifetime CA2054798C (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DEP4034982.9 1990-11-03
DE4034982A DE4034982C2 (en) 1990-11-03 1990-11-03 Synthetic polypeptides for the determination of HCV antibodies and HCV antigens, agents therefor and their use in these detection methods
DE4112743A DE4112743C2 (en) 1991-04-19 1991-04-19 Synthetic core peptides for the determination of HCV antibodies and HCV antigens, agents therefor and their use in these detection methods
DEP4112743.9 1991-04-19
DE4120281A DE4120281C2 (en) 1991-06-19 1991-06-19 Immunochemical method for the simultaneous detection of several different antibody specificities, peptide mixtures and test therefor
DEP4120281.3 1991-06-19
DEP4121431.5 1991-06-28
DE4121431A DE4121431A1 (en) 1991-06-28 1991-06-28 Peptide(s) for hepatitis-C virus detection

Publications (2)

Publication Number Publication Date
CA2054798A1 true CA2054798A1 (en) 1992-05-04
CA2054798C CA2054798C (en) 2009-08-18

Family

ID=27435056

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002054798A Expired - Lifetime CA2054798C (en) 1990-11-03 1991-11-01 Hcv-specific peptides, agents therefor and the use thereof

Country Status (8)

Country Link
EP (2) EP0770679B2 (en)
JP (2) JP4097162B2 (en)
AT (2) ATE206717T1 (en)
AU (1) AU657497B2 (en)
CA (1) CA2054798C (en)
DE (2) DE59109271D1 (en)
DK (2) DK0770679T4 (en)
ES (2) ES2255068T5 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104285149A (en) * 2012-03-09 2015-01-14 生物梅里埃公司 Interfering peptides and method for detecting micro-organisms

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683864A (en) * 1987-11-18 1997-11-04 Chiron Corporation Combinations of hepatitis C virus (HCV) antigens for use in immunoassays for anti-HCV antibodies
US5712087A (en) * 1990-04-04 1998-01-27 Chiron Corporation Immunoassays for anti-HCV antibodies employing combinations of hepatitis C virus (HCV) antigens
EP0489968B1 (en) * 1990-12-14 1996-11-06 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US6007982A (en) * 1990-12-14 1999-12-28 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
US5910404A (en) 1990-12-14 1999-06-08 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus
ATE167522T1 (en) * 1991-01-31 1998-07-15 Abbott Lab MONOCLONAL ANTIBODIES AGAINST POSSIBLE HCV ENVELOPE REGIONS AND METHODS OF USING THEM
GB9105871D0 (en) * 1991-03-20 1991-05-08 Inst Cientifico Tecnol Navarra Synthetic peptides
US5574132A (en) * 1991-04-05 1996-11-12 Biochem Immunosystems Inc. Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV)
WO1992022571A1 (en) * 1991-06-13 1992-12-23 Baxter Diagnostics Inc. Immunoassay for non-a non-b hepatitis
DE69232871T2 (en) * 1991-06-24 2003-05-08 Chiron Corp HEPATITIS C-VIRUS POLYPEPTIDES (HIV)
DE4209215A1 (en) 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh HCV PEPTIDE ANTIGEN AND METHOD FOR DETERMINING HCV
EP0525910A1 (en) * 1991-08-02 1993-02-03 Akzo Nobel N.V. Non-A, non-B peptide
DK0608261T3 (en) * 1991-09-13 2003-03-17 Chiron Corp Compositions with immunoreactive hepatitis C virus polypeptide
DE610436T1 (en) * 1991-11-21 1995-08-03 Common Services Agency Detection of the hepatis-C virus.
WO1993011158A2 (en) * 1991-12-06 1993-06-10 Akzo Nobel N.V. Non-a, non-b peptides
US6709828B1 (en) 1992-03-06 2004-03-23 N.V. Innogenetics S.A. Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them
BR9305435A (en) * 1992-03-06 1994-12-27 Innogenetics Nv Process for determining peptides corresponding to immunologically important epitopes and their use in a process for determining biotinylated antibodies or peptides corresponding to immunologically important epitopes, process for preparing them and compositions containing them
US6667387B1 (en) 1996-09-30 2003-12-23 N.V. Innogenetics S.A. HCV core peptides
FR2690921B1 (en) * 1992-05-06 1995-06-30 Bio Merieux SYNTHESIS POLYPEPTIDES BELONGING TO HEPATITIS C VIRUS (HCV) AND USED IN PARTICULAR FOR DETECTING THE SAME.
EP1878797B1 (en) * 1992-07-16 2010-04-28 Advanced Life Science Institute, Inc Antigenic peptides for grouping hepatitis c virus, kit comprising the same and methods for its grouping using the same
DE4240980A1 (en) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV peptide antigens and method for the determination of HCV
WO1994024560A1 (en) * 1993-04-14 1994-10-27 International Murex Technologies Corporation Immunoassay
GB2282884A (en) * 1993-04-14 1995-04-19 Int Murex Tech Corp Immunoassay
JPH07135981A (en) * 1993-05-28 1995-05-30 Eisai Co Ltd Non-a, non-b hepatitis virus gene-derived dna and polypeptide constituting the same
CA2125467C (en) * 1993-07-06 2001-02-06 Heinz Dobeli Process for producing hydrophobic polypeptides, proteins or peptides
US5670310A (en) * 1994-07-29 1997-09-23 The United States Of America As Represented By The Department Of Health And Human Services Methods and compositions for differential diagnosis of acute and chronic hepatitis c virus infection
JP3665371B2 (en) * 1994-08-31 2005-06-29 株式会社先端生命科学研究所 Epitope chimera antigen peptide for hepatitis C virus infection or group determination, production method thereof, and infection or group determination method using the same
DE19540105C1 (en) * 1995-09-19 1997-02-20 United Biomedical Inc Compsn. contg. synthetic peptide(s) reactive with hepatitis C related antibodies
DE19637718A1 (en) 1996-04-01 1997-10-02 Boehringer Mannheim Gmbh Recombinant inactive core streptavidin mutants
GB9624750D0 (en) * 1996-11-28 1997-01-15 Univ London Capture assays
FR2760367B1 (en) * 1997-03-06 1999-04-30 Pasteur Merieux Serums Vacc VACCINE COMPOSITION FOR THE PREVENTION OR TREATMENT OF HEPATITIS C
WO1999058561A1 (en) * 1998-05-14 1999-11-18 Pasteur Merieux Serums & Vaccins Hepatitis c virus mimotopes
AU2001272257A1 (en) * 2000-07-07 2002-01-21 Medmira Inc. Hcv mosaic antigen composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (en) * 1987-11-18 2000-02-23 希龙股份有限公司 Nanbv diagnostics and vaccines
US5191064A (en) * 1988-09-30 1993-03-02 The Research Foundation For Microbial Diseases (Osaka University) Non-a, non-b hepatitis virus antigen peptide
UA50829C2 (en) * 1989-03-17 2002-11-15 Чірон Корпорейшн Polynucleotide, vector, cells, expressing system, polypeptides, monoclonal antibodies, preparation of polyclonal antibodies, nucleotide probe, analytic kits, method for detecting nucleic acids, methods for immunoassay, vaccine, method for production of antibodies
WO1991004262A1 (en) * 1989-09-15 1991-04-04 National Institute Of Health Of Japan New hcv isolates
AU638304B2 (en) * 1989-12-22 1993-06-24 Abbott Laboratories Hepatitis c assay
KR940000755B1 (en) * 1990-02-16 1994-01-29 유나이티드 바이오메디칼 인코오포레이티드 Synthetic peptides specific for the detection of antibodies to hcv
AU635124B2 (en) * 1990-04-16 1993-03-11 United Biomedical Inc. Synthetic peptides specific for the detection of antibodies to HCV, diagnosis of HCV infection and prevention thereof as vaccines
CA2047792C (en) * 1990-07-26 2002-07-02 Chang Y. Wang Synthetic peptides specific for the detection of antibodies to hcv, diagnosis of hcv infection and prevention thereof as vaccines
EP0489968B1 (en) * 1990-12-14 1996-11-06 Innogenetics N.V. Synthetic antigens for the detection of antibodies to hepatitis C virus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104285149A (en) * 2012-03-09 2015-01-14 生物梅里埃公司 Interfering peptides and method for detecting micro-organisms

Also Published As

Publication number Publication date
EP0770679A2 (en) 1997-05-02
JPH04330098A (en) 1992-11-18
EP0770679B2 (en) 2009-12-30
ATE206717T1 (en) 2001-10-15
ATE318309T1 (en) 2006-03-15
DK0770679T3 (en) 2006-04-03
EP0484787A3 (en) 1992-08-12
CA2054798C (en) 2009-08-18
AU8700291A (en) 1992-05-07
JP4097162B2 (en) 2008-06-11
AU657497B2 (en) 1995-03-16
ES2255068T3 (en) 2006-06-16
JP2003192697A (en) 2003-07-09
EP0770679B1 (en) 2006-02-22
JP4097191B2 (en) 2008-06-11
EP0484787A2 (en) 1992-05-13
EP0770679A3 (en) 1997-05-21
ES2161682T3 (en) 2001-12-16
DE59109221D1 (en) 2001-11-15
ES2255068T5 (en) 2010-08-03
DK0484787T3 (en) 2002-02-04
DK0770679T4 (en) 2010-05-10
DE59109271D1 (en) 2006-04-27
EP0484787B1 (en) 2001-10-10

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Legal Events

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