CA2053803A1 - Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids - Google Patents

Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids

Info

Publication number
CA2053803A1
CA2053803A1 CA002053803A CA2053803A CA2053803A1 CA 2053803 A1 CA2053803 A1 CA 2053803A1 CA 002053803 A CA002053803 A CA 002053803A CA 2053803 A CA2053803 A CA 2053803A CA 2053803 A1 CA2053803 A1 CA 2053803A1
Authority
CA
Canada
Prior art keywords
formula
fluoropyridin
yloxy
preparation
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002053803A
Other languages
French (fr)
Other versions
CA2053803C (en
Inventor
Robert Haessig
Urs Siegrist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2053803A1 publication Critical patent/CA2053803A1/en
Application granted granted Critical
Publication of CA2053803C publication Critical patent/CA2053803C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C07D213/643—2-Phenoxypyridines; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals

Abstract

(3-Fluoropyridin-2-yloxy)phenoxypropionic acids of formula I
(See formula I) wherein X is hydrogen, fluoro, chloro, bromo or trifluoromethvl and Y is hydrogen, sodium or potassium, axe prepared by reacting a compound of formula 11
CA002053803A 1990-10-23 1991-10-21 Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids Expired - Fee Related CA2053803C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH337990 1990-10-23
CH3379/90-7 1990-10-23

Publications (2)

Publication Number Publication Date
CA2053803A1 true CA2053803A1 (en) 1992-04-24
CA2053803C CA2053803C (en) 2002-12-17

Family

ID=4254687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002053803A Expired - Fee Related CA2053803C (en) 1990-10-23 1991-10-21 Process for the preparation of (3-fluoropyridin-2-yloxy)phenoxypropionic acids

Country Status (9)

Country Link
EP (1) EP0483061B1 (en)
JP (1) JP3069810B2 (en)
KR (1) KR100212690B1 (en)
BR (1) BR9104557A (en)
CA (1) CA2053803C (en)
DE (1) DE59105515D1 (en)
IE (1) IE66342B1 (en)
IL (1) IL99805A (en)
ZA (1) ZA918408B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115108972A (en) * 2022-08-29 2022-09-27 北京迪泰医药科技有限公司 Synthetic method of 2-methyl-3-fluoro-5-bromopyridine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0305593A3 (en) * 1983-12-06 1989-10-11 Ciba-Geigy Ag Intermediates for cyanamides of 2-pyridinyloxyphenoxypropionic acid

Also Published As

Publication number Publication date
DE59105515D1 (en) 1995-06-22
KR920008001A (en) 1992-05-27
EP0483061A2 (en) 1992-04-29
EP0483061A3 (en) 1992-10-28
KR100212690B1 (en) 1999-08-02
CA2053803C (en) 2002-12-17
EP0483061B1 (en) 1995-05-17
JPH04264070A (en) 1992-09-18
IL99805A0 (en) 1992-08-18
ZA918408B (en) 1992-06-24
IE913704A1 (en) 1992-05-22
JP3069810B2 (en) 2000-07-24
IE66342B1 (en) 1995-12-27
BR9104557A (en) 1992-06-09
IL99805A (en) 1995-12-31

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