CA2039194A1 - Utilisations de l-deprenyl et de compositions qui en derivent - Google Patents

Utilisations de l-deprenyl et de compositions qui en derivent

Info

Publication number
CA2039194A1
CA2039194A1 CA2039194A CA2039194A CA2039194A1 CA 2039194 A1 CA2039194 A1 CA 2039194A1 CA 2039194 A CA2039194 A CA 2039194A CA 2039194 A CA2039194 A CA 2039194A CA 2039194 A1 CA2039194 A1 CA 2039194A1
Authority
CA
Canada
Prior art keywords
deprenyl
compositions
same
frequence
pets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2039194A
Other languages
English (en)
Other versions
CA2039194C (fr
Inventor
Norton W. Milgram
David R. Stevens
Gwendolyn O. Ivy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DEPRENYL Inc USA
Original Assignee
Deprenyl Animal Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27076843&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2039194(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/576,011 external-priority patent/US5151449A/en
Application filed by Deprenyl Animal Health Inc filed Critical Deprenyl Animal Health Inc
Publication of CA2039194A1 publication Critical patent/CA2039194A1/fr
Application granted granted Critical
Publication of CA2039194C publication Critical patent/CA2039194C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Thin Film Transistor (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pulse Circuits (AREA)
  • Electrotherapy Devices (AREA)
CA002039194A 1990-08-31 1991-03-27 Utilisations de l-deprenyl et de compositions qui en derivent Expired - Lifetime CA2039194C (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/576,011 1990-08-31
US07/576,011 US5151449A (en) 1990-08-31 1990-08-31 Use of L-deprenyl for retention of specific physiological functions
US64345291A 1991-01-18 1991-01-18
US07/643,452 1991-01-18

Publications (2)

Publication Number Publication Date
CA2039194A1 true CA2039194A1 (fr) 1992-03-01
CA2039194C CA2039194C (fr) 1997-01-28

Family

ID=27076843

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002039194A Expired - Lifetime CA2039194C (fr) 1990-08-31 1991-03-27 Utilisations de l-deprenyl et de compositions qui en derivent

Country Status (16)

Country Link
US (2) US5276057A (fr)
EP (2) EP0473252B1 (fr)
JP (3) JP2819072B2 (fr)
AT (2) ATE181501T1 (fr)
AU (1) AU633714B2 (fr)
BR (1) BR9103506A (fr)
CA (1) CA2039194C (fr)
DE (2) DE69131386T2 (fr)
DK (2) DK0473252T3 (fr)
ES (2) ES2135123T3 (fr)
GR (2) GR3022971T3 (fr)
HK (1) HK1011611A1 (fr)
ID (1) ID19492A (fr)
MX (1) MX9100067A (fr)
MY (2) MY110217A (fr)
NZ (1) NZ238277A (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2039194C (fr) * 1990-08-31 1997-01-28 Norton W. Milgram Utilisations de l-deprenyl et de compositions qui en derivent
US5561163A (en) * 1990-08-31 1996-10-01 Deprenyl Animal Health, Inc. Treating hearing loss with deprenyl
US5565495A (en) * 1990-08-31 1996-10-15 Deprenyl Animal Health, Inc. Method for survival curve shifting in dogs
CA2107552C (fr) * 1991-04-04 2001-08-28 William G. Tatton Utilisation du deprenyl pour le maintien, la prevention de la perte et la recuperation de la fonction nerveuse
US5444095A (en) * 1991-04-04 1995-08-22 University Of Toronto, Innovations Foundation Use of deprenyl to rescue damaged nerve cells
US5767164A (en) * 1991-04-04 1998-06-16 Innovations Foundation Use of deprenyl to rescue damaged nerve cells
US5844003A (en) * 1991-04-04 1998-12-01 Innovations Foundation Use of deprenyl compounds to maintain, prevent loss, or recover nerve cell function
US5242950A (en) * 1992-04-23 1993-09-07 Somerset Pharmaceuticals, Inc. Treatment of macular degeneration
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
ES2149850T3 (es) * 1993-05-04 2000-11-16 Ceva Sante Animale Utilizacion de la selegilina en medicina veterinaria.
FR2704756B1 (fr) * 1993-05-04 1995-07-28 Sanofi Elf Utilisation de la sélégiline en médecine vétérinaire.
WO1996022068A2 (fr) 1995-01-13 1996-07-25 Somerset Pharmaceuticals, Inc. Procedes et compositions pharmaceutiques utilisant de la desmethylselegiline
US6033682A (en) 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
EP0808160A1 (fr) * 1995-02-10 1997-11-26 The University Of Toronto Innovations Foundation Composes deprenyle pour le traitement du glaucome
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
NZ309980A (en) * 1995-06-07 2001-06-29 Noven Pharma Transdermal composition containing a blend of one or more polymers, one or more drugs that has a low molecular weight and is liquid at room temperature
EP0866691B2 (fr) * 1995-11-06 2005-01-26 Somerset Pharmaceuticals, Inc. Administration sublinguale et buccale de selegiline
BR9908713A (pt) * 1998-03-16 2000-11-21 Somerset Pharmaceuticals Inc Uso de selegilina ou desmetil-selegilina para tratamento de feridas, queimaduras e danos dermatológicos
US20030212144A1 (en) * 2001-07-18 2003-11-13 Mohankumar Sheba J.J. Method for inducing an estrous cycle and pregnancy in a female mammal
US8058442B2 (en) * 2002-11-07 2011-11-15 Technion Research And Development Foundation Ltd. Neuroprotective iron chelators and pharmaceutical compositions comprising them
JP2006524708A (ja) * 2003-04-25 2006-11-02 インディヴァス ファーマシューティカルズ，インコーポレーテッド 塩化トロスピウムの投与により連続睡眠を促進するための方法
US8097608B2 (en) * 2003-11-25 2012-01-17 Technion Research And Development Foundation Ltd. Methods for treatment of cardiovascular disorders and diseases
WO2005051371A1 (fr) * 2003-11-25 2005-06-09 Technion Research & Development Foundation Ltd. Compositions et procedes pour traiter des troubles et des maladies cardiovasculaires
JP2005232148A (ja) * 2004-02-03 2005-09-02 Technion Research & Development Foundation Ltd 神経保護剤としてプロパルギルアミンの使用
FR2884421B1 (fr) 2005-04-15 2007-08-10 Virbac Sa Nouveaux moyens de regulation des troubles du comportement chez les animaux de compagnie
US8263655B2 (en) 2005-10-06 2012-09-11 Technion Research And Development Foundation Ltd Methods for treatment of renal failure
RU2518455C2 (ru) 2009-12-29 2014-06-10 Хилл`С Пет Ньютришн, Инк. Включающие пируват составы для домашних животных и способы их применения
TR201909277T4 (tr) 2010-02-03 2019-07-22 Pharma Two B Ltd Rasajilinin genişletilmiş salınım formülasyonları ve kullanım alanları.
CN103860503A (zh) * 2012-12-10 2014-06-18 天津市汉康医药生物技术有限公司 一种治疗帕金森病的缓释药物组合物及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA871155A (en) * 1971-05-18 Chinoin Gyogyszer-Es Vegyeszeti Termekek Gyara Rt Optically active phenyl isopropylamine derivatives having pharmaceutical properties and their preparation
HU187775B (en) * 1982-07-14 1986-02-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu New process for producing propargile-amines of pharmaceutical activity
US4916151A (en) * 1985-12-05 1990-04-10 Merrell Dow Pharmaceuticals Inc. Method of treating parkinson's syndrome
US4871550A (en) * 1986-09-05 1989-10-03 Millman Phillip L Nutrient composition for athletes and method of making and using the same
US4880883A (en) * 1987-06-03 1989-11-14 Wisconsin Alumni Research Foundation Biocompatible polyurethanes modified with lower alkyl sulfonate and lower alkyl carboxylate
US4861800A (en) * 1987-08-18 1989-08-29 Buyske Donald A Method for administering the drug deprenyl so as to minimize the danger of side effects
HU208484B (en) * 1988-08-17 1993-11-29 Chinoin Gyogyszer Es Vegyeszet Process for producing pharmaceutical composition containing acid additional salt of selegilin as active component for treating schisofrenia
CA2039194C (fr) * 1990-08-31 1997-01-28 Norton W. Milgram Utilisations de l-deprenyl et de compositions qui en derivent
US5192808A (en) * 1990-08-31 1993-03-09 Deprenyl Animal Health, Inc. Therapeutic effect of L-deprenyl in the management of pituitary-dependent hyperadrenocorticism (cushing's disease)

Also Published As

Publication number Publication date
ES2097790T3 (es) 1997-04-16
EP0732101A1 (fr) 1996-09-18
JPH04230624A (ja) 1992-08-19
JP2884501B2 (ja) 1999-04-19
DE69131386D1 (de) 1999-07-29
MX9100067A (es) 1992-04-01
ATE149350T1 (de) 1997-03-15
ATE181501T1 (de) 1999-07-15
DE69131386T2 (de) 1999-11-25
CA2039194C (fr) 1997-01-28
US5387615A (en) 1995-02-07
DK0732101T3 (da) 1999-11-22
ES2135123T3 (es) 1999-10-16
JP2884500B2 (ja) 1999-04-19
JP2819072B2 (ja) 1998-10-30
EP0473252A3 (en) 1992-08-05
EP0732101B1 (fr) 1999-06-23
US5276057A (en) 1994-01-04
BR9103506A (pt) 1992-05-12
GR3031263T3 (en) 1999-12-31
DK0473252T3 (da) 1997-09-15
EP0473252B1 (fr) 1997-03-05
EP0473252A2 (fr) 1992-03-04
HK1011611A1 (en) 1999-07-16
MY124210A (en) 2006-06-30
ID19492A (id) 1998-07-16
DE69124875T2 (de) 1997-06-26
AU633714B2 (en) 1993-02-04
NZ238277A (en) 1993-10-26
JPH09328423A (ja) 1997-12-22
GR3022971T3 (en) 1997-06-30
AU7395791A (en) 1992-03-05
DE69124875D1 (de) 1997-04-10
JPH09328422A (ja) 1997-12-22
MY110217A (en) 1998-03-31

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Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry