CA2012137A1 - Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase - Google Patents
Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenaseInfo
- Publication number
- CA2012137A1 CA2012137A1 CA2012137A CA2012137A CA2012137A1 CA 2012137 A1 CA2012137 A1 CA 2012137A1 CA 2012137 A CA2012137 A CA 2012137A CA 2012137 A CA2012137 A CA 2012137A CA 2012137 A1 CA2012137 A1 CA 2012137A1
- Authority
- CA
- Canada
- Prior art keywords
- inhibitors
- lipoxygenase
- dibenzoheterocyclic
- hydroxamic acids
- hydroxy ureas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Compounds having the formula I:
(see formula I) are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
(see formula I) are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002012137A CA2012137C (en) | 1990-03-14 | 1990-03-14 | Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/493,527 US5036067A (en) | 1990-03-14 | 1990-03-14 | Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase |
CA002012137A CA2012137C (en) | 1990-03-14 | 1990-03-14 | Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2012137A1 true CA2012137A1 (en) | 1991-09-14 |
CA2012137C CA2012137C (en) | 2000-08-08 |
Family
ID=25674010
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002012137A Expired - Fee Related CA2012137C (en) | 1990-03-14 | 1990-03-14 | Dibenzoheterocyclic hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2012137C (en) |
-
1990
- 1990-03-14 CA CA002012137A patent/CA2012137C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2012137C (en) | 2000-08-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |