CA2012062A1 - Methode de mesure de l'activite des glycosyltransferases et son utilisation - Google Patents

Methode de mesure de l'activite des glycosyltransferases et son utilisation

Info

Publication number
CA2012062A1
CA2012062A1 CA002012062A CA2012062A CA2012062A1 CA 2012062 A1 CA2012062 A1 CA 2012062A1 CA 002012062 A CA002012062 A CA 002012062A CA 2012062 A CA2012062 A CA 2012062A CA 2012062 A1 CA2012062 A1 CA 2012062A1
Authority
CA
Canada
Prior art keywords
reaction product
antibody
sugar
specimen
lectin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002012062A
Other languages
English (en)
Inventor
Shin Yazawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Sumitomo Seika Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Seika Chemicals Co Ltd filed Critical Sumitomo Seika Chemicals Co Ltd
Publication of CA2012062A1 publication Critical patent/CA2012062A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57469Immunoassay; Biospecific binding assay; Materials therefor for cancer involving tumor associated glycolinkage, i.e. TAG
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002012062A 1989-03-15 1990-03-13 Methode de mesure de l'activite des glycosyltransferases et son utilisation Abandoned CA2012062A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6445789 1989-03-15
JP64457/1989 1989-03-15

Publications (1)

Publication Number Publication Date
CA2012062A1 true CA2012062A1 (fr) 1990-09-15

Family

ID=13258789

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002012062A Abandoned CA2012062A1 (fr) 1989-03-15 1990-03-13 Methode de mesure de l'activite des glycosyltransferases et son utilisation

Country Status (4)

Country Link
EP (1) EP0387875B1 (fr)
KR (1) KR900014589A (fr)
CA (1) CA2012062A1 (fr)
DE (1) DE69022867T2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5403717A (en) * 1987-08-11 1995-04-04 Pacific Northwest Research Diagnosis of premalignant or malignant conditions of human secretory epithelia
FR2679034A1 (fr) * 1991-07-10 1993-01-15 Centre Nat Rech Scient Determination de la malignite des cellules de tumeurs humaines ou animales, au moyen de lectines endogenes.
WO1994010340A1 (fr) * 1992-10-30 1994-05-11 Mt. Sinai Hospital Corporation Procede de mesure de l'activite de la glycosyltransferase
EP0656422B1 (fr) * 1993-11-05 2000-04-26 Amersham Pharmacia Biotech UK Limited Essai de chloramphenicol-acetyl-transférase (CAT)
DE69424132T2 (de) * 1993-11-05 2000-09-21 Amersham Pharmacia Biotech Uk Ltd., Little Chalfont Chloramphenicol Acetyl Transferase (CAT) Nachweis
US5861318A (en) * 1994-11-16 1999-01-19 Pharmacia & Upjohn Company Scintillation proximity assay for N-acetylgalactosaminyltransferase activity
GB9519393D0 (en) * 1995-09-22 1995-11-22 Univ Edinburgh Novel compounds and assay method
DE10122452A1 (de) * 2001-05-09 2003-02-27 Jerini Ag Verfahren zum Nachweis der enzymatischen Aktivität von Glycosyltransferasen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3070194D1 (en) * 1979-04-16 1985-03-28 Massachusetts Inst Technology An in vitro method for determining malignancy in mammalian tissue
JPS63152998A (ja) * 1986-12-16 1988-06-25 Konica Corp 糖転移酵素の測定方法

Also Published As

Publication number Publication date
EP0387875B1 (fr) 1995-10-11
DE69022867D1 (de) 1995-11-16
EP0387875A2 (fr) 1990-09-19
DE69022867T2 (de) 1996-04-18
EP0387875A3 (fr) 1992-12-16
KR900014589A (ko) 1990-10-24

Similar Documents

Publication Publication Date Title
CA1314810C (fr) Systeme heterologue pour la detection d'adn marque chimiquement et d'autres materiaux biologiques fournissant des fractions receptrices ou cibles
van Remoortere et al. Various stages of Schistosoma express Lewis^ x, LacdiNAc, GalNAcbeta1-4 (Fucalpha1-3) GlcNAc and GalNAcbeta1-4 (Fucalpha1-2 Fucalpha1-3) GlcNAc carbohydrate epitopes: detection with monoclonal antibodies that are characterized by enzymatically synthesized neoglycoproteins
Palcic et al. Enzymic synthesis of oligosaccharides terminating in the tumor-associated sialyl-Lewis-a determinant
EP0782710B1 (fr) Procede pour detecter des anticorps
CN101900735B (zh) 用于测定高半胱氨酸的方法
FI95752B (fi) Määrityskitti ja -menetelmä kokonaisten solujen immunologiseen määritykseen
EP0387875B1 (fr) Méthode de détermination d'activités de glycosyltransférases et son utilisation
US5376531A (en) Method of detecting cancer
Zatta et al. A solid-phase assay for β-1, 4-galactosyltransferase activity in human serum using recombinant aequorin
JPH03500925A (ja) タンパク質のグリコシル化のアツセイ
JP3208668B2 (ja) チロシン燐酸化及び脱燐酸化活性を測定するための方法及びキツト
Wei et al. Structural modification of H histo-blood group antigen
WO2007001021A1 (fr) Procédé de détermination de l'activité enzymatique
Lubov'S et al. An enzyme-linked lectin assay for α1, 3-galactosyltransferase
EP0392808A2 (fr) Essai de luminescence enzymologique
Räbinä et al. A time-resolved immunofluorometric method for the measurement of sialyl Lewis x-synthesizing α1, 3-fucosyltransferase activity
JPH0421819B2 (fr)
Oubihi et al. Development of an enzyme-linked immunosorbent assay-based method for measuring galactosyltransferase activity using a synthetic glycopolymer acceptor substrate
Yazawa et al. Use of benzyl 2-acetamido-2-deoxy-3-O-(2-O-methyl-β-d-galactosyl)-β-d-glucopyranoside [2′-O-methyllacto-N-biosel βBn] as a specific acceptor for GDP-fucose: N-acetylglucosaminide α (1→ 4)-l-fucosyltransferase
Remoortere et al. Various stages of Schistosoma express Lewisx, LacdiNAc, GalNAcβ1–4 (Fucα1–3) GlcNAc and GalNAcβ1–4 (Fucα1–2Fucα1–3) GlcNAc carbohydrate epitopes: detection with monoclonal antibodies that are characterized by enzymatically synthesized neoglycoproteins
US5173407A (en) Method for measuring glycosyltransferase
JPH0315761A (ja) 糖転移酵素の活性測定方法およびその用途
Vázquez-Martín et al. Elevation of ST6Gal I activity in malignant and transitional tissue in human colorectal cancer
EP0040728A1 (fr) Méthodes d'essai comportant des réactions d'affinité biospécifique
JPH1132796A (ja) 糖転移酵素活性の測定法

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead