CA2003382A1 - Method for treating vascular diseases - Google Patents
Method for treating vascular diseasesInfo
- Publication number
- CA2003382A1 CA2003382A1 CA002003382A CA2003382A CA2003382A1 CA 2003382 A1 CA2003382 A1 CA 2003382A1 CA 002003382 A CA002003382 A CA 002003382A CA 2003382 A CA2003382 A CA 2003382A CA 2003382 A1 CA2003382 A1 CA 2003382A1
- Authority
- CA
- Canada
- Prior art keywords
- amino
- alkyl
- loweralkyl
- substituted
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27515188A | 1988-11-21 | 1988-11-21 | |
US275,151 | 1988-11-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2003382A1 true CA2003382A1 (en) | 1990-05-21 |
Family
ID=23051068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002003382A Abandoned CA2003382A1 (en) | 1988-11-21 | 1989-11-20 | Method for treating vascular diseases |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0444156A4 (el) |
CA (1) | CA2003382A1 (el) |
GR (1) | GR1001145B (el) |
WO (1) | WO1990005531A1 (el) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE68045B1 (en) * | 1990-05-11 | 1996-05-15 | Abbott Lab | Renin inhibitors |
US5244910A (en) * | 1990-08-15 | 1993-09-14 | Abbott Laboratories | Renin inhibitors |
ZA921381B (en) * | 1991-03-01 | 1992-11-25 | Fujisawa Pharmaceutical Co | New use of amino acid derivatives |
SE9903028D0 (sv) * | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
DE60022525T2 (de) * | 1999-08-30 | 2006-06-14 | Sanofi Aventis Deutschland | Ramipril zur vorbeugung von kardiovaskulären vorfällen |
EP1358178A2 (en) | 2001-01-30 | 2003-11-05 | Bristol-Myers Squibb Company | Sulfonamide lactam inhibitors of factor xa |
PL3464336T3 (pl) | 2016-06-01 | 2022-05-16 | Athira Pharma, Inc. | Związki |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3418491A1 (de) * | 1984-05-18 | 1985-11-21 | Merck Patent Gmbh, 6100 Darmstadt | Diaminosaeurederivate |
DE3438545A1 (de) * | 1984-10-20 | 1986-04-24 | Merck Patent Gmbh, 6100 Darmstadt | Peptide |
DE3538749A1 (de) * | 1985-10-31 | 1987-05-07 | Merck Patent Gmbh | Peptide |
DE3626130A1 (de) * | 1986-08-01 | 1988-02-11 | Merck Patent Gmbh | Aminosaeurederivate |
DE3640535A1 (de) * | 1986-11-27 | 1988-06-01 | Merck Patent Gmbh | Peptide |
US7490044B2 (en) * | 2004-06-08 | 2009-02-10 | Bose Corporation | Audio signal processing |
-
1989
- 1989-11-20 WO PCT/US1989/005248 patent/WO1990005531A1/en not_active Application Discontinuation
- 1989-11-20 EP EP19900901238 patent/EP0444156A4/en not_active Withdrawn
- 1989-11-20 CA CA002003382A patent/CA2003382A1/en not_active Abandoned
- 1989-11-21 GR GR890100773A patent/GR1001145B/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0444156A1 (en) | 1991-09-04 |
GR1001145B (el) | 1993-05-24 |
EP0444156A4 (en) | 1992-12-09 |
WO1990005531A1 (en) | 1990-05-31 |
GR890100773A (en) | 1990-12-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |