CA1341566C - Reponse immune a des tumeurs induite par des anticorps anti-idiotypes - Google Patents

Reponse immune a des tumeurs induite par des anticorps anti-idiotypes

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Publication number
CA1341566C
CA1341566C CA000616029A CA1341566A CA1341566C CA 1341566 C CA1341566 C CA 1341566C CA 000616029 A CA000616029 A CA 000616029A CA 1341566 A CA1341566 A CA 1341566A CA 1341566 C CA1341566 C CA 1341566C
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CA
Canada
Prior art keywords
antibody
idiotype
antibodies
mab
epitope
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA000616029A
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English (en)
Inventor
Hilary Koprowski
Dorothee Herlyn
Elaine Defreitas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wistar Institute of Anatomy and Biology
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Wistar Institute of Anatomy and Biology
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Publication of CA1341566C publication Critical patent/CA1341566C/fr
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Des anticorps anti-idiotypes, leur production et leur utilisation pour l'induction de réponse immunologique aux tumeurs sont décrits. Les anticorps supportent une image interne d'un épitope présent dans une cellule tumorale solide, dans laquelle ledit anticorps anti-idiotype : (a) immuno-réagit à travers son parotope avec un anticorps monoclonal spécifique audit épitope de cellule tumorale solide, et (b) va induire la formation d'anticorps anti-idiotypes spécifiques audit épitope de cellule tumorale solide lors de l'administration à un humain.
CA000616029A 1983-11-07 1984-11-06 Reponse immune a des tumeurs induite par des anticorps anti-idiotypes Active CA1341566C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54950583A 1983-11-07 1983-11-07
US549,505 1983-11-07

Publications (1)

Publication Number Publication Date
CA1341566C true CA1341566C (fr) 2007-12-18

Family

ID=24193287

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000616029A Active CA1341566C (fr) 1983-11-07 1984-11-06 Reponse immune a des tumeurs induite par des anticorps anti-idiotypes

Country Status (4)

Country Link
JP (1) JPH0720884B2 (fr)
CA (1) CA1341566C (fr)
PH (1) PH25303A (fr)
ZA (1) ZA848713B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1255586A (fr) * 1984-07-24 1989-06-13 Hendrik M. Geysen Methode de dosage de mimotopes
US5614610A (en) * 1984-12-21 1997-03-25 Oncogen Tumor immunotherapy using anti-idiotypic antibodies

Also Published As

Publication number Publication date
JPS61500611A (ja) 1986-04-03
ZA848713B (en) 1986-06-25
JPH0720884B2 (ja) 1995-03-08
PH25303A (en) 1991-04-30

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