CA1341252C - Interferon-.beta.2a humain et interferon-.beta.2b humain; vecteurs contenant des genes correspondant a ces interferons: lignees cellulaires produisant ces interferons, ainsi que l'utilisation de ces interferons comme produits pharmaceutiques - Google Patents

Interferon-.beta.2a humain et interferon-.beta.2b humain; vecteurs contenant des genes correspondant a ces interferons: lignees cellulaires produisant ces interferons, ainsi que l'utilisation de ces interferons comme produits pharmaceutiques

Info

Publication number
CA1341252C
CA1341252C CA000617130A CA617130A CA1341252C CA 1341252 C CA1341252 C CA 1341252C CA 000617130 A CA000617130 A CA 000617130A CA 617130 A CA617130 A CA 617130A CA 1341252 C CA1341252 C CA 1341252C
Authority
CA
Canada
Prior art keywords
leu
glu
ser
gln
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA000617130A
Other languages
English (en)
Inventor
Michel Revel
Asher Zilberstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Priority claimed from CA000520275A external-priority patent/CA1341369C/fr
Application granted granted Critical
Publication of CA1341252C publication Critical patent/CA1341252C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA000617130A 1986-10-10 1986-10-10 Interferon-.beta.2a humain et interferon-.beta.2b humain; vecteurs contenant des genes correspondant a ces interferons: lignees cellulaires produisant ces interferons, ainsi que l'utilisation de ces interferons comme produits pharmaceutiques Expired - Lifetime CA1341252C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000520275A CA1341369C (fr) 1985-10-14 1986-10-10 Interferons .beta.2a et .beta.2b humains; vecteurs contenant des genes codant pour lesdits interferons, lignees de cellules les produisant et utilisation desdits interferons a titre de medicament

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA000520275A Division CA1341369C (fr) 1985-10-14 1986-10-10 Interferons .beta.2a et .beta.2b humains; vecteurs contenant des genes codant pour lesdits interferons, lignees de cellules les produisant et utilisation desdits interferons a titre de medicament

Publications (1)

Publication Number Publication Date
CA1341252C true CA1341252C (fr) 2001-06-12

Family

ID=4134134

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000617130A Expired - Lifetime CA1341252C (fr) 1986-10-10 1986-10-10 Interferon-.beta.2a humain et interferon-.beta.2b humain; vecteurs contenant des genes correspondant a ces interferons: lignees cellulaires produisant ces interferons, ainsi que l'utilisation de ces interferons comme produits pharmaceutiques

Country Status (1)

Country Link
CA (1) CA1341252C (fr)

Similar Documents

Publication Publication Date Title
US5554513A (en) Production of recombinant human interferon-beta2
Taniguchi et al. The nucleotide sequence of human fibroblast interferon cDNA
US4889803A (en) Production of interferon gamma
EP0220574B2 (fr) Interféron bêta2A humain; vecteurs contenant des gènes codant pour ledit interféron, lignées de cellules le produisant et utilisation dudit interféron à titre de médicament
Capon et al. Two distinct families of human and bovine interferon-α genes are coordinately expressed and encode functional polypeptides
Zilberstein et al. Structure and expression of cDNA and genes for human interferon‐beta‐2, a distinct species inducible by growth‐stimulatory cytokines.
JP2515308B2 (ja) ヒト免疫インタ−フエロン
Poupart et al. B cell growth modulating and differentiating activity of recombinant human 26‐kd protein (BSF‐2, HuIFN‐beta 2, HPGF).
Charleston et al. An interferon-induced Mx protein: cDNA sequence and high-level expression in the endometrium of pregnant sheep
Yelverton et al. Bacterial synthesis of a novel human leukocyte interferon
Derynck et al. Isolation and structure of a human fibroblast interferon gene
Ohno et al. Structure of a chromosomal gene for human interferon β
US5004689A (en) DNA sequences, recombinant DNA molecules and processes for producing human gamma interferon-like polypeptides in high yields
EP0750668A1 (fr) NOUVELLES MUTEINES D'INTERFERON $g(b)
Leung et al. The structure and bacterial expression of three distinct bovine interferon-β genes
CHERNAJOVSKY et al. Efficient constitutive production of human fibroblast interferon by hamster cells transformed with the IFN-β1 gene fused to an SV40 early promoter
Mory et al. Efficient constitutive production of human IFN-γ in Chinese hamster ovary cells
JP2648860B2 (ja) ヒトインターフエロン−β２Ａ及びヒトインターフエロン−β２Ｂ、該インターフエロンをコードする遺伝子を含むベクター、該インターフエロンを産生するセルライン及び該インターフエロンの医薬品としての用途
Coulombel et al. Isolation and characterization of a novel interferon-α-encoding gene, IFN-α11 within a murine IFN cluster
US4939088A (en) Sustained production of recombinant gamma interferon using an Epstein-Barr virus replicon
US5510472A (en) Production of recombinant human interferon-beta2
Haas et al. Constitutive monocyte-restricted activity of NF-M, a nuclear factor that binds to a C/EBP motif.
CA1341252C (fr) Interferon-.beta.2a humain et interferon-.beta.2b humain; vecteurs contenant des genes correspondant a ces interferons: lignees cellulaires produisant ces interferons, ainsi que l'utilisation de ces interferons comme produits pharmaceutiques
EP0174143A1 (fr) Famille distincte d'interférons de leucocytes humains, compositions les contenant, méthodes pour leur production et ADN et hôtes transfectés pour ces méthodes
KR100382628B1 (ko) 인터페론α/β결합단백질과이의제조및용도

Legal Events

Date Code Title Description
MKEX Expiry

Effective date: 20180612