CA1244708A - Infant formulas - Google Patents

Infant formulas

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Publication number
CA1244708A
CA1244708A CA000433971A CA433971A CA1244708A CA 1244708 A CA1244708 A CA 1244708A CA 000433971 A CA000433971 A CA 000433971A CA 433971 A CA433971 A CA 433971A CA 1244708 A CA1244708 A CA 1244708A
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CA
Canada
Prior art keywords
fatty acids
omega
formula
oil
total
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000433971A
Other languages
French (fr)
Inventor
Michael T. Clandinin
Janet E. Chappell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovations Foundation of University of Toronto
Wyeth LLC
Original Assignee
Innovations Foundation of University of Toronto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innovations Foundation of University of Toronto filed Critical Innovations Foundation of University of Toronto
Application granted granted Critical
Publication of CA1244708A publication Critical patent/CA1244708A/en
Expired legal-status Critical Current

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Abstract

ABSTRACT OF THE DISCLOSURE

An edible fat product is provided for incorp-oration in a formula suitable for feeding infants. The product comprises at least one of the following:
(a) at least one member of the group of C20, .omega.-6 fatty acids and C22,.omega.-6 fatty acids, wherein the total of said C20,.omega.-6 and said C22,.omega.-6 fatty acids is about 0.13-5.6% by weight of all fatty acids in the pro-duct;
(b) at least one member of the group of C20, .omega.-3 fatty acids and C22,.omega.-3 fatty acids, wherein the total of said C20,.omega.-3 and said C22,.omega.-3 fatty acids is about 0.013-3.33% by weight of all fatty acids in the product.
A formula is also provided which is suit-able for feeding infants. The formula comprises at least one of the following:
(a) prostaglandin E2 in a concentration of about 50-1000 nanograms per 100 mls. of the formula;
(b) 6-keto prostaglandin F1? in a concentra-tion of about 20-300 nanograms per 100 mls. of the formula;
(c) prostaglandin F2? in a concentration of about 25-300 nanograms per 100 mls. of the formula.

Claims (41)

THE EMBODIMENTS OF THE INVENTION IN WHICH AN EXCLUSIVE
PROPERTY OR PRIVILEGE IS CLAIMED ARE DEFINED AS FOLLOWS:
1. An edible fat product for incorporation in a formula suitable for feeding infants, said product comprising at least one of the following:
a) at least one member of the group of C20,.omega.-6 fatty acids and C22,.omega.-6 fatty acids, wherein the total of said C20,.omega.-6 and said C22,.omega.-6 fatty acids is about 0.13-5.6% by weight of all fatty acids in the product;
b) at least one member of the group of C20,.omega.-3 fatty acids and C22,.omega.-3 fatty acids, wherein the total of said C20,.omega.-3 and said C22,.omega.-3 fatty acids is about 0.013.3-33%
by weight of all fatty acids in the product.
2. An edible fat product for incorporation in a formula suitable for feeding infants, said product comprising at least one of the following:
a) a fatty acid source of semi-purified or purified origin containing at least one member of the group of C20,.omega.-6 fatty acids and C22,.omega.-6 fatty acids, wherein the total of said C20,.omega.-6 fatty acids is about 0.13% -5.6% by weight of all fatty acids in the product; and b) a fatty acid source of semi-purified or purified origin containing at least one member of the group of C20,.omega.-3 fatty acids and C22,.omega.-3 fatty acids, wherein the total of said C20,.omega.-3 and said C22,.omega.-3 fatty acids is about 0.013% - 3.33% by weight of all fatty acids in the product.
3. An edible fat product as claimed in claim 1 or 2, which includes C22, .omega.-3 fatty acids in the amount of 0.013-2.22% by weight of all fatty acids in the product.
4. An edible fat product as claimed in claim 1 or 2, which includes C20, .omega.-6 fatty acids and C22, .omega.-6 fatty acids, wherein the total of said C20,.omega.-6 and said C22, .omega.-6 fatty acids is about 0.39-3.9% by weight of all fatty acids in the product.
5. An edible fat product as claimed in claim 1 or 2, which includes C20, .omega.-3 fatty acids and C22, .omega.-3 fatty acids, wherein the total of said C20, .omega.-3 and said C22, .omega.-3 fatty acids is about 0.05-1.39% by weight of all fatty acids in the product.
6. An edible fat product as claimed in claim 1 or 2, which includes C22, .omega.-3 fatty acids in the amount of about 0.05-1.39% by weight of all fatty acids in the product.
7. A formula suitable for feeding infants, comprising sugar, non-fat milk, water and an edible fat, said fat comprising at least one of a) at least one member of the group of C20, .omega.-6 fatty acids and C22, .omega.-6 fatty acids, wherein the total of said C20, .omega.-6 and said C22, .omega.-6 fatty acids is about 5-100 mg.
per 100 mls. of the formula;
b) at least one member of the group of C20, .omega.-3 fatty acids and C22, .omega.-3 fatty acids, wherein the total of said C20, .omega.-3 and said C22, .omega.-3 fatty acids is about 0.5-60 mg.
per 100 mls. of the formula.
8. A formula suitable for feeding infants, comprising:
sugar, non-fat milk, water and an edible fat, said fat comprising at least one of a) a fatty acid source of semi-purified or purified origin containing at least one member of the group of C20,.omega.-6 fatty acids and C22,.omega.-6 fatty acids, wherein the total of said C20,.omega.-6 and said C22,.omega.-6 fatty acids is about 5 - 100 mg. per 100 mls. of the formula;
and b) a fatty acid source of semi-purified or purified origin containing at least one member of the group of C20,.omega.-3 fatty acids and C22,.omega.-3 fatty acids, wherein the total of said C20,.omega.-3 and said C22,.omega.-3 fatty acids is about 0.5 - 60 mg. per 100 mls. of the formula.
9. A formula as claimed in claim 7 or 8, which includes C22,.omega.-3 fatty acids in the amount of about 0.5-40 mg.
per 100 mls. of the formula.
10. A formula as claimed in claim 7 or 8, which includes C20,.omega.-6 fatty acids and C22,.omega.-6 fatty acids, wherein the total of said C20,.omega.-6 and said C22,.omega.-6 fatty acids is about 15-70 mg. per 100 mls. of the formula.
11. A formula as claimed in claim 7 or 8, which includes C20,.omega.-3 fatty acids and C22,.omega.-3 fatty acids wherein the total of said C20,.omega.-3 and said C22,.omega.-3 fatty acids is about 2-25 mg. per 100 mls. of the formula.
12. A formula as claimed in claim 7 or 8, which includes C22,.omega.-3 fatty acids in the amount of about 2-25 mg. per 100 mls. of the formula.
13. An edible fat product as claimed in claim 1 or 2, which includes a fatty acid from each of group (a) and (b).
14. A formula as claimed in claim 7 or 8, which includes a fatty acid from each of group (a) and (b).
15. A formula as claimed in claim 7 or 8, wherein the total concentration of fatty acids in the formula is about 1.8-3.8 gm. per 100 mls. of the formula.
16. A formula as claimed in claim 7 or 8, wherein a portion of the fatty acids are derived from egg yolk lipid.
17. An edible fat product as claimed in claim 1 or 2, wherein a portion of the fatty acids are derived from egg yolk lipid.
18. A formula as claimed in claim 7 or 8, wherein each 100 mls. of the formula contains a total of about 5-80 mg.
of C20:4,.omega.-6 fatty acids, about 1-40 mg. of C22:6,.omega.-3 fatty acids, and about 0.5-15 mg. of C20:5,.omega.-3 fatty acids.
19. A formula as claimed in claim 7 or 8, wherein each 100 mls. of the formula contains a total of about 10-70 mg.
of C20:4,.omega.-6 fatty acids, about 5-22 mg. of C22:6,.omega.-3 fatty acids, and about 2-8 mg. of C20:5,.omega.-3 fatty acids.
20. An edible fat product as claimed in claim 1 or 2, wherein the total of C20:4,.omega.-6 fatty acids is about 0.13-4.44%, the total of C22:6.omega.-3 fatty acids is about 0.02-2.22%, and the total of C20:5,.omega.-3 fatty acids is about 0.01-0.83%, by weight of all fatty acids in the fat product.
21. An edible fat product as claimed in claim 1 or 2, wherein the total of C20:4, .omega.-6 fatty acids is about 0.26-3.9%, the total of C22:6, .omega.-3 fatty acids is about 0.13-1.22%, and the total of C20:5, .omega.-3 fatty acids is about 0.05-0.44%, by weight o all fatty acids in the fat product.
22. A formula as claimed in claim 7, wherein a portion of the fatty acids are derived from a blend of egg yolk lipid and at least one member of the group of coconut oil and soyabean oil.
23. A formula as claimed in claim 22, wherein:
the egg yolk lipid in the blend is about 75-95 parts by weight; and the total of the coconut oil and soyabean oil in the blend is about 5-25 parts by weight.
24. A formula as claimed in claim 23, wherein the total concentration of fatty acids in the formula is about 1.8-3.8 gm. per 100 mls. of the formula, and wherein substantially all fatty acids in the formula are derived from said blend.
25. An edible fat product as claimed in claim 1 or 2, wherein a portion of the fatty acids are derived from a blend of egg yolk lipid and at least one member of the group of coconut oil and soyabean oil.
26. An edible fat product as claimed in claim 1 or 2, wherein a portion of the fatty acids are derived from a blend of egg yolk lipid and at least one member of the group of coconut oil and soyabean oil, and wherein:

the egg yolk lipid in the blend is about 75-95 parts by weight; and the total of the coconut oil and the soyabean oil in the blend is about 5-25 parts by weight.
27. A formula as claimed in claim 7, wherein a portion of the fatty acids are derived from a mixture sub-stantially approximating in composition a blend of egg yolk lipid and at least one member of the group of coconut oil and soyabean oil.
28. A formula as claimed in claim 27, which further includes a protein, water, minerals, and vitamins.
29. A process for the preparation of an edible fat product for incorporation into a formula suitable for feeding infants, said process comprising:
adding to one or both of coconut oil and soyabean oil at least one of a) at least one member of the group of C20, .omega.-6 fatty acids and C22, .omega.-6 fatty acids, wherein the total of said C20, .omega.-6 and said C22, .omega.-6 fatty acids is about 0.13 - 5.6% by weight of all fatty acids in the product;
and b) at least one member of the group of C20, .omega.-3 fatty acids and C22, .omega.-3 fatty acids, wherein the total of said C20, .omega.-3 and said C22, .omega.-3 fatty acids is about 0.013 -3.33% by weight of all fatty acids in the product.
30. A process as claimed in claim 29, wherein said fatty acids are derived from egg yolk lipid.
31. An edible fat for use in preparing a formula suitable for feeding infants, said fat comprising: a blend of egg yolk lipid and an oil selected from the group consisting of coconut oil, soyabean oil and mixtures thereof, wherein said egg yolk lipid and oil are present in amounts sufficient to provide an amount of C20, .omega.-6 and C22, .omega.-6 fatty acids of about 0.13 - 5.6% by weight of all fatty acids in the product and an amount of C20, .omega.-3 and C22, .omega.-3 fatty acids of about 0.013 - 3.33%
by weight of all fatty acids in the product.
32. An edible fat product as claimed in claim 31, wherein the egg yolk lipid in the blend is about 75 - 95 parts by weight and the total of the coconut oil and the soyabean oil in the blend is about 5 -25 parts by weight.
33. A formula suitable for feeding infants, comprising:
protein, carbohydrate, water, minerals, vitamins and an edible fat, said fat comprising a blend of egg yolk lipid and an oil selected from the group consisting of coconut oil, soyabean oil and mixtures thereof, wherein said egg yolk lipid and oil are present in amounts sufficient to provide an amount of C20, .omega.-6 and C22, .omega.-6 fatty acids of about 5 - 100 mg. per 100 mls. of the formula and an amount of C20, .omega.-3 and C22, .omega.-3 fatty acids of about 0.5 to 60 mg. per 100 mls. of the formula.
34. An edible fat product as claimed in claim 33, wherein the egg yolk lipid in the blend is about 75 - 95 parts by weight and the total of the coconut oil and the soyabean oil in the blend is about 5 - 25 parts by weight.
35. A formula as claimed in claim 34, wherein the total concentration of fatty acids in the formula is about 1.8 - 3.8 gm. per 100 mls. of the formula.
36. A formula as claimed in claim 34, wherein the total concentration of fatty acids in the formula is about 1.8 - 3.8 gm. per 100 mls. of the formula, and whereby substantially all fatty acids in the formula are derived from said blend.
37. A formula as claimed in claim 7 or 8, comprising sugar, non-fat milk, water and at least one of a) prostaglandin E2 in a concentration of about 50-1000 nanograms per 100 mls. of the formula;
b) 6-keto prostaglandin F1? in a concentration of about 20-300 nanograms per 100 mls. of the formula;
c) prostaglandin F2? in a concentration of about 25-300 nanograms per 100 mls. of the formula.
38. An edible fat for use in preparing a formula suitable for feeding infants, said fat comprising:
a blend of fish oil and a vegetable oil, wherein said oils are present in amounts sufficient to provide an amount of C20, .omega.-6 and C22,.omega.-6 fatty acids of about 0.13 - 5.6% by weight of all fatty acids in the product, and an amount of C20,.omega.-3 and C22,.omega.-3 fatty acids of about 0.013-3.33% by weight of all fatty acids in the product.
39. An edible fat product as claimed in claim 44, wherein the vegetable oil is a blend of cocoa oil, palm oil, oreo oil, sunflower oil, coconut oil and soyabean oil.
40. A formula suitable for feeding infants, comprising:
protein, carbohydrate, water, minerals, vitamins and an edible fat, said fat comprising a blend of fish oil and a vegetable oil, wherein said oils are present in amounts sufficient to provide an amount of C20,.omega.-6 and C22,.omega.-6 fatty acids of about 5-100 mg. per 100 mls. of the formula and an amount of C20, .omega.-3 and C22,.omega.-3 fatty acids of about 0.5 - 60 mg. per 100 mls. of the formula.
41. A formula as claimed in claim 46, wherein the vegetable oil is a blend of cocoa oil, palm oil, oreo oil, sunflower oil, coconut oil and soyabean oil.
CA000433971A 1982-08-06 1983-08-05 Infant formulas Expired CA1244708A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40584982A 1982-08-06 1982-08-06
US405,849 1982-08-06

Publications (1)

Publication Number Publication Date
CA1244708A true CA1244708A (en) 1988-11-15

Family

ID=23605500

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000433971A Expired CA1244708A (en) 1982-08-06 1983-08-05 Infant formulas

Country Status (1)

Country Link
CA (1) CA1244708A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0705539A2 (en) 1994-10-06 1996-04-10 Friesland Brands B.V. A food for pregnant and lactating women

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0705539A2 (en) 1994-10-06 1996-04-10 Friesland Brands B.V. A food for pregnant and lactating women

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