CA1212057A - Acetaminophen analogs, antigens and antibodies - Google Patents

Acetaminophen analogs, antigens and antibodies

Info

Publication number
CA1212057A
CA1212057A CA000425141A CA425141A CA1212057A CA 1212057 A CA1212057 A CA 1212057A CA 000425141 A CA000425141 A CA 000425141A CA 425141 A CA425141 A CA 425141A CA 1212057 A CA1212057 A CA 1212057A
Authority
CA
Canada
Prior art keywords
compound according
amino acid
carbon atoms
poly
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000425141A
Other languages
English (en)
French (fr)
Inventor
Pyare Khanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Application granted granted Critical
Publication of CA1212057A publication Critical patent/CA1212057A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9486—Analgesics, e.g. opiates, aspirine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA000425141A 1982-04-02 1983-04-05 Acetaminophen analogs, antigens and antibodies Expired CA1212057A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US364,836 1982-04-02
US06/364,836 US4424150A (en) 1982-04-02 1982-04-02 Acetaminophen analogs, antigens, and antibodies

Publications (1)

Publication Number Publication Date
CA1212057A true CA1212057A (en) 1986-09-30

Family

ID=23436305

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000425141A Expired CA1212057A (en) 1982-04-02 1983-04-05 Acetaminophen analogs, antigens and antibodies

Country Status (6)

Country Link
US (1) US4424150A (enExample)
EP (1) EP0095229B1 (enExample)
JP (1) JPS58192854A (enExample)
AT (1) ATE41414T1 (enExample)
CA (1) CA1212057A (enExample)
DE (1) DE3379400D1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0201633A3 (en) * 1984-12-20 1989-02-22 Abbott Laboratories Substituted anilide compounds and their use
JPS62205095A (ja) * 1986-03-04 1987-09-09 Toyo Jozo Co Ltd 新生理活性物質アルドスタチンおよびその製造法
US4828983A (en) * 1986-07-10 1989-05-09 Eastman Kodak Company Use of phenols and anilines to increase the rate of peroxidase catalyzed oxidation of leuco dyes
US5047318A (en) * 1988-06-13 1991-09-10 Eastman Kodak Company Imidazole leuco dye composition containing 4'-hydroxyacetanilide, diagnostic kit and method using same
EP0386644B1 (en) * 1989-03-10 1997-06-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Reagents for the determination of drugs
US6015683A (en) * 1992-07-15 2000-01-18 Clinical Diagnostic Systems, Inc. Dry analytical element for acetaminophen assay
US5372932A (en) * 1992-12-22 1994-12-13 Eastman Kodak Company Analytical element and method for the determination of a specific binding ligand using a 4-hydroxy or 4-alkoxyarylacetamide as stabilizer
US5372931A (en) * 1992-12-22 1994-12-13 Eastman Kodak Company Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods
US20090263839A1 (en) * 2008-04-21 2009-10-22 Board Of Trustees Of The University Of Arkansas Acetaminophen-protein adduct assay device and method
WO2015123574A1 (en) 2014-02-14 2015-08-20 The Board Of Trustees Of The University Of Arkansas Acetaminophen protein adducts and methods of use thereof
CA2967037A1 (en) 2014-12-03 2016-06-09 Bioventures, Llc Anti-acetaminophen antibodies and acetaminophen protein adducts
CN113248596B (zh) * 2021-04-15 2022-12-16 华南农业大学 一种可同时检测对乙酰氨基酚和非那西丁的人工抗原、抗体及其制备方法和应用
CN113121389A (zh) * 2021-04-27 2021-07-16 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） 一种苯胺类药物快速检测试剂盒及其制备方法与应用
CN115232022B (zh) * 2022-08-02 2024-01-30 梯尔希（南京）药物研发有限公司 一种对乙酰氨基酚二聚体衍生物的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975342A (en) 1972-05-15 1976-08-17 Biological Developments, Inc. Tyrosyl-class antigenic conjugates, their preparation and antibodies raised thereto
US3981863A (en) 1975-02-25 1976-09-21 Micromedic Diagonistics, Inc. Cyanocobalamin derivatives

Also Published As

Publication number Publication date
ATE41414T1 (de) 1989-04-15
EP0095229A3 (en) 1985-04-10
EP0095229B1 (en) 1989-03-15
JPS58192854A (ja) 1983-11-10
JPH0460103B2 (enExample) 1992-09-25
DE3379400D1 (en) 1989-04-20
EP0095229A2 (en) 1983-11-30
US4424150A (en) 1984-01-03

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Legal Events

Date Code Title Description
MKEX Expiry