CA1208937A - Systeme de numeration des particules pour un dispositif de fractionnement - Google Patents
Systeme de numeration des particules pour un dispositif de fractionnementInfo
- Publication number
- CA1208937A CA1208937A CA000449103A CA449103A CA1208937A CA 1208937 A CA1208937 A CA 1208937A CA 000449103 A CA000449103 A CA 000449103A CA 449103 A CA449103 A CA 449103A CA 1208937 A CA1208937 A CA 1208937A
- Authority
- CA
- Canada
- Prior art keywords
- particles
- particle
- nature
- counting
- sample
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002245 particle Substances 0.000 title claims abstract description 165
- 238000009826 distribution Methods 0.000 claims abstract description 21
- 238000000034 method Methods 0.000 claims abstract description 13
- 238000005194 fractionation Methods 0.000 claims description 9
- 230000007246 mechanism Effects 0.000 claims description 8
- 238000000926 separation method Methods 0.000 claims description 8
- 230000000704 physical effect Effects 0.000 claims 1
- 230000005855 radiation Effects 0.000 description 18
- 239000012530 fluid Substances 0.000 description 13
- 230000003287 optical effect Effects 0.000 description 11
- 150000002500 ions Chemical class 0.000 description 9
- 239000000463 material Substances 0.000 description 6
- 238000004062 sedimentation Methods 0.000 description 6
- 238000001514 detection method Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 238000005259 measurement Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000002398 sedimentation field-flow fractionation Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 238000002835 absorbance Methods 0.000 description 2
- 201000009310 astigmatism Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000005375 photometry Methods 0.000 description 2
- 238000002471 steric field-flow fractionation Methods 0.000 description 2
- 238000005303 weighing Methods 0.000 description 2
- ZXVONLUNISGICL-UHFFFAOYSA-N 4,6-dinitro-o-cresol Chemical compound CC1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O ZXVONLUNISGICL-UHFFFAOYSA-N 0.000 description 1
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 description 1
- 241000168096 Glareolidae Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 description 1
- 239000006229 carbon black Substances 0.000 description 1
- 235000019241 carbon black Nutrition 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005670 electromagnetic radiation Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 229910052734 helium Inorganic materials 0.000 description 1
- 239000001307 helium Substances 0.000 description 1
- SWQJXJOGLNCZEY-UHFFFAOYSA-N helium atom Chemical compound [He] SWQJXJOGLNCZEY-UHFFFAOYSA-N 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000000976 ink Substances 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229910052754 neon Inorganic materials 0.000 description 1
- GKAOGPIIYCISHV-UHFFFAOYSA-N neon atom Chemical compound [Ne] GKAOGPIIYCISHV-UHFFFAOYSA-N 0.000 description 1
- 239000013618 particulate matter Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- ZMRUPTIKESYGQW-UHFFFAOYSA-N propranolol hydrochloride Chemical compound [H+].[Cl-].C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 ZMRUPTIKESYGQW-UHFFFAOYSA-N 0.000 description 1
- 239000005297 pyrex Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 238000009877 rendering Methods 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1486—Counting the particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N2015/1493—Particle size
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N2021/4704—Angular selective
Landscapes
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Combined Means For Separation Of Solids (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47448183A | 1983-03-11 | 1983-03-11 | |
| US474,481 | 1983-03-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1208937A true CA1208937A (fr) | 1986-08-05 |
Family
ID=23883709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000449103A Expired CA1208937A (fr) | 1983-03-11 | 1984-03-08 | Systeme de numeration des particules pour un dispositif de fractionnement |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0118897A3 (fr) |
| JP (1) | JPS59173733A (fr) |
| CA (1) | CA1208937A (fr) |
| DK (1) | DK146284A (fr) |
| GR (1) | GR81949B (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2348085T3 (es) * | 2003-07-02 | 2010-11-30 | Caridianbct, Inc. | Sistema de control y monitorizacion para el procesamiento de sangre. |
| JP5427586B2 (ja) * | 2009-12-19 | 2014-02-26 | 三菱重工業株式会社 | 油中水分除去装置および油中水分除去方法 |
| GB201216121D0 (en) * | 2012-09-10 | 2012-10-24 | Novartis Ag | Sample quantification by disc centrifugation |
| ITUD20120137A1 (it) * | 2012-07-31 | 2014-02-01 | Alifax Holding S P A | Apparato e procedimento per la determinazione della velocita' di sedimentazione del sangue e di altri parametri ad essa correlati |
| GB201304631D0 (en) * | 2013-03-14 | 2013-05-01 | Malvern Instr Ltd | Monomer detection in protein separation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4350292A (en) * | 1979-12-27 | 1982-09-21 | Coulter Electronics, Inc. | Centrifugal feeder |
| US4284497A (en) * | 1980-02-29 | 1981-08-18 | E. I. Du Pont De Nemours And Company | Rotor for sedimentation field flow fractionation |
-
1984
- 1984-02-29 DK DK146284A patent/DK146284A/da not_active IP Right Cessation
- 1984-03-08 CA CA000449103A patent/CA1208937A/fr not_active Expired
- 1984-03-09 JP JP4415184A patent/JPS59173733A/ja active Pending
- 1984-03-09 EP EP84102565A patent/EP0118897A3/fr not_active Withdrawn
- 1984-03-09 GR GR74043A patent/GR81949B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR81949B (fr) | 1984-12-12 |
| EP0118897A2 (fr) | 1984-09-19 |
| DK146284A (da) | 1984-09-12 |
| EP0118897A3 (fr) | 1988-01-07 |
| JPS59173733A (ja) | 1984-10-01 |
| DK146284D0 (da) | 1984-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |