CA1208237A - Process for preparing 6-(lower alkoxy)-5- (trifluoromethyl)-1-naphthalenecarboxylic acid - Google Patents

Process for preparing 6-(lower alkoxy)-5- (trifluoromethyl)-1-naphthalenecarboxylic acid

Info

Publication number
CA1208237A
CA1208237A CA000413919A CA413919A CA1208237A CA 1208237 A CA1208237 A CA 1208237A CA 000413919 A CA000413919 A CA 000413919A CA 413919 A CA413919 A CA 413919A CA 1208237 A CA1208237 A CA 1208237A
Authority
CA
Canada
Prior art keywords
trifluoromethyl
methyl
acid
naphthalene
lower alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000413919A
Other languages
English (en)
French (fr)
Inventor
Kazimir Sestanj
Steven Fung
Nedumparambil A. Abraham
Francesco Bellini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Canada Inc
Original Assignee
Ayerst Mckenna and Harrison Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc
Application granted granted Critical
Publication of CA1208237A publication Critical patent/CA1208237A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2632—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving an organo-magnesium compound, e.g. Grignard synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/58—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of halogen, e.g. by hydrogenolysis, splitting-off
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/06—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by conversion of non-aromatic six-membered rings or of such rings formed in situ into aromatic six-membered rings, e.g. by dehydrogenation
    • C07C37/07—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by conversion of non-aromatic six-membered rings or of such rings formed in situ into aromatic six-membered rings, e.g. by dehydrogenation with simultaneous reduction of C=O group in that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/213—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C49/217—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the aromatic rings
    • C07C49/223—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the aromatic rings polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000413919A 1981-11-13 1982-10-21 Process for preparing 6-(lower alkoxy)-5- (trifluoromethyl)-1-naphthalenecarboxylic acid Expired CA1208237A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/321,302 US4408077A (en) 1981-11-13 1981-11-13 6-(Lower alkoxy)-5-(trifluoromethyl)-1-naphthalenecarboxaldehydes
US321,302 1981-11-13

Publications (1)

Publication Number Publication Date
CA1208237A true CA1208237A (en) 1986-07-22

Family

ID=23250042

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000413919A Expired CA1208237A (en) 1981-11-13 1982-10-21 Process for preparing 6-(lower alkoxy)-5- (trifluoromethyl)-1-naphthalenecarboxylic acid

Country Status (6)

Country Link
US (1) US4408077A (OSRAM)
AT (1) AT391690B (OSRAM)
CA (1) CA1208237A (OSRAM)
DK (1) DK161510C (OSRAM)
GR (1) GR77378B (OSRAM)
HU (1) HU187811B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499310A (en) * 1981-11-13 1985-02-12 Ayerst, Mckenna & Harrison, Inc. 5-Methyl-1-(trifluoromethyl)-2-naphthalenol, process for its preparation and ethers thereof
US4590010A (en) * 1985-04-18 1986-05-20 Ethyl Corporation Substituted naphthoic acid process
US4662065A (en) * 1986-05-22 1987-05-05 Battery Engineering, Inc. Method for dehydrating manganese dioxide
GB8915104D0 (en) * 1989-06-30 1989-08-23 Beecham Group Plc Chemical process
JP4038024B2 (ja) * 2001-03-12 2008-01-23 住友化学株式会社 １−クロロ−４−アリールブタン類の製造方法
DE10135027A1 (de) * 2001-07-18 2003-02-06 Solvay Pharm Gmbh Verwendung Trifluoracetylalkyl-substituierter Phenyl-, Phenol- und Benzoylderivate in der Behandlung und/oder Prophylaxe von Obestias und deren Begleit- und/oder Folgeerkrankungen
AT510165B1 (de) * 2010-09-23 2012-02-15 Inova Lisec Technologiezentrum Verfahren zum herstellen von mit einem von luft verschiedenen gas gefülltem isolierglas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391186A (en) * 1964-06-16 1968-07-02 Scient Ind De L Ile De France Benzoic acids
US3977949A (en) * 1975-07-07 1976-08-31 Columbia Chemical Corporation Acidic plating bath and additives for electrodeposition of bright tin

Also Published As

Publication number Publication date
DK161510C (da) 1991-12-23
DK161510B (da) 1991-07-15
AT391690B (de) 1990-11-12
US4408077A (en) 1983-10-04
GR77378B (OSRAM) 1984-09-11
HU187811B (en) 1986-02-28
ATA408982A (de) 1990-05-15
DK506782A (da) 1983-05-14

Similar Documents

Publication Publication Date Title
JP3921238B2 (ja) ベンゾイル誘導体及びその合成
CA1137486A (en) Process for the preparation of 2,5-bis(2,2,2- trifluoroethoxy)-n-(2-piperidylmethyl) benzamidee
CA1208237A (en) Process for preparing 6-(lower alkoxy)-5- (trifluoromethyl)-1-naphthalenecarboxylic acid
US4326087A (en) 3-Bromo-4-fluoro-benzyl derivatives
Sato et al. Jasmonoid synthesis from cis-4-heptenoic acid.
US4551557A (en) Bromination of substituted benzaldehydes
Katritzky et al. A novel synthesis of esters via substitution of the benzotriazolyl group in 1-(benzotriazol-1-yl) alkyl esters with organozinc reagents
WO2008127560A1 (en) Process for making galantamine
US4499310A (en) 5-Methyl-1-(trifluoromethyl)-2-naphthalenol, process for its preparation and ethers thereof
US4172960A (en) Process for preparing pyrogallol
US5600008A (en) Benzoyl derivatives and synthesis thereof
US5248816A (en) Process for making 2-hydroxymandelic acid and 2-hydroxybenzaldehydes
EP1308432B1 (en) Process for the preparation of 5- (4-chlorophenyl)-methyl|-2,2-dimethylcyclopentanone
US6054605A (en) 2, 3-dihalogeno-6-trifluoromethylbenzene derivatives and process for producing the same
HU190628B (en) Process for preparing 3-vinyl-substituted 2,2-dimethyl-cyclopropane-1-carboxylic acids and and their esters
AU703688B2 (en) Process for producing 3,5-diaryl pyrazolene
US4761508A (en) 1,1-(3-ethylphenyl)phenylethylene and method for preparing it
EP0772579B1 (en) Benzoyl derivatives and synthesis thereof
EP0037698A1 (en) Benzaldehyde derivatives for use as a chemical intermediate
US4713485A (en) Process for preparing α-hydroxy-alkanoic acids and compounds obtained by this process
HU199420B (en) Process for producing 5-halogen-6-aminonicotinic acid halides
RU2258060C2 (ru) Способ получения 5-[(4-хлорфенил)метил]-2,2-диметилциклопентанона
JP2595089B2 (ja) ３―フエノキシベンジル２―（４―ジフルオロハロメトキシフェニル）―２―メチルプロピルエーテル誘導体の製造法
US6054624A (en) 2,3-dihalogeno-6-trifluoromethylbenzene derivatives and process for producing the same
US4675419A (en) Process for preparing α-hydroxy-acids and compounds obtained by this process

Legal Events

Date Code Title Description
MKEX Expiry