CA1207737A - Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix - Google Patents
Transfer of macromolecules from a chromatographic substrate to an immobilizing matrixInfo
- Publication number
- CA1207737A CA1207737A CA000428218A CA428218A CA1207737A CA 1207737 A CA1207737 A CA 1207737A CA 000428218 A CA000428218 A CA 000428218A CA 428218 A CA428218 A CA 428218A CA 1207737 A CA1207737 A CA 1207737A
- Authority
- CA
- Canada
- Prior art keywords
- membrane
- modifying agent
- charge modifying
- charge
- microporous membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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Classifications
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- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0081—After-treatment of organic or inorganic membranes
- B01D67/0093—Chemical modification
- B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
- B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/56—Polyamides, e.g. polyester-amides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/3272—Polymers obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3268—Macromolecular compounds
- B01J20/328—Polymers on the carrier being further modified
- B01J20/3282—Crosslinked polymers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2323/00—Details relating to membrane preparation
- B01D2323/30—Cross-linking
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Transplantation (AREA)
- Inorganic Chemistry (AREA)
- Food Science & Technology (AREA)
- Manufacturing & Machinery (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Electrochemistry (AREA)
- Environmental & Geological Engineering (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Peptides Or Proteins (AREA)
- Sewing Machines And Sewing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/464,609 US4512896A (en) | 1983-02-07 | 1983-02-07 | Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix |
| US464,609 | 1983-02-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1207737A true CA1207737A (en) | 1986-07-15 |
Family
ID=23844591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000428218A Expired CA1207737A (en) | 1983-02-07 | 1983-05-16 | Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4512896A (enExample) |
| EP (1) | EP0138841B1 (enExample) |
| JP (1) | JPS60501126A (enExample) |
| AU (1) | AU577276B2 (enExample) |
| CA (1) | CA1207737A (enExample) |
| DE (2) | DE3486313T2 (enExample) |
| FR (1) | FR2540629B1 (enExample) |
| IL (1) | IL70866A (enExample) |
| WO (1) | WO1984003055A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4601828A (en) * | 1983-02-07 | 1986-07-22 | Yale University | Transfer of macromolecules from a chromatographic substrate to an immobilizing matrix |
| USRE34457E (en) * | 1983-12-28 | 1993-11-30 | Daicel Chemical Industries, Inc. | Separating agent |
| USRE38435E1 (en) * | 1983-12-28 | 2004-02-24 | Daicel Chemical Industries, Ltd. | Separating agent |
| JPS60142930A (ja) * | 1983-12-28 | 1985-07-29 | Daicel Chem Ind Ltd | 分離剤 |
| FR2586689B1 (fr) * | 1985-09-02 | 1990-06-08 | Plant Genetic Systems Nv | Moyens et procedes de transfert de proteines sur une surface receptrice supportee |
| EP0214909A1 (fr) * | 1985-09-02 | 1987-03-18 | Plant Genetic Systems N.V. | Moyens et procedes de transfert de proteines et/ou d'acides nucleiques sur une surface receptrice supportee |
| US4806546A (en) * | 1985-09-30 | 1989-02-21 | Miles Inc. | Immobilization of nucleic acids on derivatized nylon supports |
| US4997537A (en) * | 1986-10-21 | 1991-03-05 | Northeastern University | High performance microcapillary gel electrophoresis |
| US5665216A (en) * | 1986-10-21 | 1997-09-09 | Northeastern University | Capillary column for high performance electrophoretic separation and detection of SDS proteins and system and using the same |
| DE3736087C2 (de) * | 1987-10-24 | 1997-03-06 | Serva Feinbiochem Gmbh & Co | Gewebe zur Herstellung von Elektrophoresegelen |
| US5114585A (en) * | 1988-03-01 | 1992-05-19 | Gelman Sciences, Inc. | Charged porous filter |
| EP0436547B1 (en) * | 1988-05-10 | 1994-11-30 | E.I. Du Pont De Nemours And Company | Process for rapid nucleic acid detection |
| US5374524A (en) * | 1988-05-10 | 1994-12-20 | E. I. Du Pont De Nemours And Company | Solution sandwich hybridization, capture and detection of amplified nucleic acids |
| US5004543A (en) * | 1988-06-21 | 1991-04-02 | Millipore Corporation | Charge-modified hydrophobic membrane materials and method for making the same |
| US5075220A (en) * | 1988-10-07 | 1991-12-24 | Eastman Kodak Company | Determination of a chlamydial or gonococcal antigen using a positively-charged ionically binding support |
| US5004806A (en) * | 1988-10-17 | 1991-04-02 | Molecular Devices Corporation | Nitrocellulose filtration to remove proteins from polynucleotides |
| US5683916A (en) * | 1988-10-31 | 1997-11-04 | Hemasure Inc. | Membrane affinity apparatus and purification methods related thereto |
| US4957620A (en) * | 1988-11-15 | 1990-09-18 | Hoechst Celanese Corporation | Liquid chromatography using microporous hollow fibers |
| US4981591A (en) * | 1989-04-07 | 1991-01-01 | Cuno, Incorporated | Cationic charge modified filter media |
| GB8921818D0 (en) * | 1989-09-27 | 1989-11-08 | Astromed Ltd | Treatment of carbohydrates |
| US5269931A (en) * | 1990-09-17 | 1993-12-14 | Gelman Sciences Inc. | Cationic charge modified microporous membranes |
| US5151189A (en) * | 1990-09-17 | 1992-09-29 | Gelman Sciences, Inc. | Cationic charge modified microporous membrane |
| US5543054A (en) * | 1993-11-24 | 1996-08-06 | Millipore Corporation | Method and apparatus for covalent immobilization of charge- conjugated carbohydrate molecules |
| US5728301A (en) * | 1994-09-29 | 1998-03-17 | Truett; William L. | Apparatus and method for thin layer chromatography |
| US5714359A (en) * | 1995-10-12 | 1998-02-03 | The University Of Akron | Apparatus and method for electrostatic endothelial cell seeding in a vascular prosthesis |
| US6010573A (en) * | 1998-07-01 | 2000-01-04 | Virginia Commonwealth University | Apparatus and method for endothelial cell seeding/transfection of intravascular stents |
| JP2000180442A (ja) * | 1998-12-15 | 2000-06-30 | Fuji Photo Film Co Ltd | 血液濾過器 |
| US6780327B1 (en) * | 1999-02-25 | 2004-08-24 | Pall Corporation | Positively charged membrane |
| US6680208B1 (en) * | 1999-11-19 | 2004-01-20 | Becton, Dickinson And Company | Rapid protein identification using antibody mixtures |
| US7846746B2 (en) * | 2001-04-10 | 2010-12-07 | Children's Medical Center Corporation | Methods of analysis and labeling of protein-protein interactions |
| US20030038081A1 (en) * | 2001-08-14 | 2003-02-27 | I-Fan Wang | High strength asymmetric cellulosic membrane |
| US20030036085A1 (en) * | 2002-08-19 | 2003-02-20 | Salinaro Richard F | Membranes |
| SG150501A1 (en) * | 2004-02-05 | 2009-03-30 | Millipore Corp | Porous adsorptive or chromatographic media |
| MX2007001821A (es) * | 2004-08-13 | 2007-07-16 | Univ Mcmaster | Material compuesto que contiene un polimero en gel no reticulado. |
| BRPI0516161A (pt) | 2004-09-30 | 2008-08-26 | Univ Mcmaster | material compósito, e, aparelho de filtração |
| GB0702504D0 (en) * | 2007-02-09 | 2007-03-21 | Ge Healthcare Bio Sciences Ab | Cross-linked cellulose membranes |
| US9433922B2 (en) | 2007-08-14 | 2016-09-06 | Emd Millipore Corporation | Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same |
| US20090130738A1 (en) * | 2007-11-19 | 2009-05-21 | Mikhail Kozlov | Media for membrane ion exchange chromatography |
| US8277649B2 (en) * | 2009-12-14 | 2012-10-02 | General Electric Company | Membranes and associated methods for purification of antibodies |
| CN113692420B (zh) * | 2019-04-08 | 2023-09-12 | 旭化成医疗株式会社 | 用于纯化含蛋白质的溶液的聚酰胺介质及其制造方法 |
| CN111675825B (zh) * | 2020-06-09 | 2022-06-24 | 大连工业大学 | 一种附有胰蛋白酶的微孔膜的制备方法及其在蛋白水解中的应用 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL110447C (enExample) | 1957-09-05 | |||
| US2926154A (en) | 1957-09-05 | 1960-02-23 | Hercules Powder Co Ltd | Cationic thermosetting polyamide-epichlorohydrin resins and process of making same |
| US3224986A (en) | 1962-04-18 | 1965-12-21 | Hercules Powder Co Ltd | Cationic epichlorohydrin modified polyamide reacted with water-soluble polymers |
| DE1792083A1 (de) * | 1968-07-19 | 1971-04-29 | Merck Anlagen Gmbh | Zweischichtenplatte und ihre Verwendung zur duennschichtchromatographischen Auftrennung von Aminosaeuren |
| US3769968A (en) | 1971-11-22 | 1973-11-06 | L Blount | Speculum |
| JPS4887119A (enExample) | 1972-02-24 | 1973-11-16 | ||
| US3875044A (en) * | 1972-06-09 | 1975-04-01 | Marine Colloids Inc | Hydratable gel sheets |
| US3878100A (en) * | 1973-02-01 | 1975-04-15 | Marine Colloids Inc | Separation medium |
| US3876738A (en) | 1973-07-18 | 1975-04-08 | Amf Inc | Process for producing microporous films and products |
| US3928517A (en) | 1973-12-26 | 1975-12-23 | Amf Inc | Quench bath regeneration system for microporous film production |
| DE2861803D1 (en) * | 1977-06-15 | 1982-07-01 | Nat Res Dev | Electrophoresis membranes, their use in a separation method and separation apparatus |
| ZA792326B (en) | 1978-05-15 | 1980-06-25 | Pall Corp | Process for preparing polyamide membrane filter media and product |
| JPS54155892A (en) * | 1978-05-29 | 1979-12-08 | Ohashi Mochihiko | Device for concentration electrophoresis |
| JPS56115727A (en) * | 1980-02-19 | 1981-09-11 | Kuraray Co Ltd | Carrier for immobilizing physiologically active substance |
| US4357311A (en) * | 1980-10-03 | 1982-11-02 | Warner-Lambert Company | Substrate for immunoassay and means of preparing same |
| WO1982001477A1 (en) * | 1980-10-27 | 1982-05-13 | Inc Amf | Charge modified microporous membrane,process for charge modifying said membrane and process for filtration of fluid |
| CH649718A5 (de) * | 1981-03-25 | 1985-06-14 | Aligena Ag | Verfahren zur herstellung von semipermeablen membranen aus polymeren auf acrylnitrilbasis, die nach diesem verfahren hergestellten membranen und ihre verwendung. |
| US4473475A (en) | 1981-05-29 | 1984-09-25 | Amf Inc. | Charge modified microporous membrane, process for charge modifying said membrane, and process for filtration of fluids |
| US4415428A (en) * | 1982-01-27 | 1983-11-15 | Fmc Corporation | Support for electrophoresis and method of producing same |
| NL8203102A (nl) * | 1982-08-04 | 1984-03-01 | Katholieke Universiteit Facult | Papier voor rna-blotting; werkwijze voor het maken daarvan; toepassingen van het papier. |
-
1983
- 1983-02-07 US US06/464,609 patent/US4512896A/en not_active Expired - Lifetime
- 1983-05-16 CA CA000428218A patent/CA1207737A/en not_active Expired
-
1984
- 1984-01-27 DE DE3486313T patent/DE3486313T2/de not_active Revoked
- 1984-01-27 AU AU24978/84A patent/AU577276B2/en not_active Ceased
- 1984-01-27 EP EP84900827A patent/EP0138841B1/en not_active Revoked
- 1984-01-27 JP JP59500904A patent/JPS60501126A/ja active Granted
- 1984-01-27 DE DE84900827T patent/DE3486231T2/de not_active Revoked
- 1984-01-27 WO PCT/US1984/000139 patent/WO1984003055A1/en not_active Ceased
- 1984-02-03 IL IL70866A patent/IL70866A/xx not_active IP Right Cessation
- 1984-02-07 FR FR8401805A patent/FR2540629B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3486313T2 (de) | 1994-11-10 |
| EP0138841A1 (en) | 1985-05-02 |
| EP0138841A4 (en) | 1987-12-01 |
| JPH0376868B2 (enExample) | 1991-12-06 |
| AU2497884A (en) | 1984-08-30 |
| DE3486231T2 (de) | 1994-04-14 |
| AU577276B2 (en) | 1988-09-22 |
| JPS60501126A (ja) | 1985-07-18 |
| FR2540629A1 (fr) | 1984-08-10 |
| US4512896A (en) | 1985-04-23 |
| WO1984003055A1 (en) | 1984-08-16 |
| IL70866A (en) | 1987-09-16 |
| IL70866A0 (en) | 1984-05-31 |
| DE3486231D1 (de) | 1993-11-25 |
| FR2540629B1 (fr) | 1989-09-22 |
| EP0138841B1 (en) | 1993-10-20 |
| DE3486313D1 (de) | 1994-07-07 |
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