CA1206559A - Method of and apparatus for detecting change in the breakoff point of a droplet generation system - Google Patents
Method of and apparatus for detecting change in the breakoff point of a droplet generation systemInfo
- Publication number
- CA1206559A CA1206559A CA000421053A CA421053A CA1206559A CA 1206559 A CA1206559 A CA 1206559A CA 000421053 A CA000421053 A CA 000421053A CA 421053 A CA421053 A CA 421053A CA 1206559 A CA1206559 A CA 1206559A
- Authority
- CA
- Canada
- Prior art keywords
- stream
- radiation
- jet stream
- amplitude
- undulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000008859 change Effects 0.000 title claims abstract description 39
- 238000000034 method Methods 0.000 title claims abstract description 16
- 239000002245 particle Substances 0.000 claims abstract description 40
- 239000007788 liquid Substances 0.000 claims abstract description 15
- 230000005855 radiation Effects 0.000 claims description 45
- 239000006194 liquid suspension Substances 0.000 claims description 7
- 230000006872 improvement Effects 0.000 claims description 6
- 210000004027 cell Anatomy 0.000 description 12
- 239000013078 crystal Substances 0.000 description 10
- 230000000694 effects Effects 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 239000012530 fluid Substances 0.000 description 5
- 238000012937 correction Methods 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 238000011144 upstream manufacturing Methods 0.000 description 3
- NOQGZXFMHARMLW-UHFFFAOYSA-N Daminozide Chemical compound CN(C)NC(=O)CCC(O)=O NOQGZXFMHARMLW-UHFFFAOYSA-N 0.000 description 2
- 210000000601 blood cell Anatomy 0.000 description 2
- 239000003990 capacitor Substances 0.000 description 2
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- 241000331231 Amorphocerini gen. n. 1 DAD-2008 Species 0.000 description 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 description 1
- 101100536354 Drosophila melanogaster tant gene Proteins 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- PBAYDYUZOSNJGU-UHFFFAOYSA-N chelidonic acid Natural products OC(=O)C1=CC(=O)C=C(C(O)=O)O1 PBAYDYUZOSNJGU-UHFFFAOYSA-N 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000000684 flow cytometry Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- HCTVWSOKIJULET-LQDWTQKMSA-M phenoxymethylpenicillin potassium Chemical compound [K+].N([C@H]1[C@H]2SC([C@@H](N2C1=O)C([O-])=O)(C)C)C(=O)COC1=CC=CC=C1 HCTVWSOKIJULET-LQDWTQKMSA-M 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000004513 sizing Methods 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/149—Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1404—Handling flow, e.g. hydrodynamic focusing
- G01N2015/1406—Control of droplet point
Landscapes
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Dispersion Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833307789 DE3307789A1 (de) | 1983-03-04 | 1983-03-04 | Verfahren und vorrichtung zur anzeige einer aenderung des zerfallpunktes in einem tropfenerzeugungssystem |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1206559A true CA1206559A (en) | 1986-06-24 |
Family
ID=6192580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000421053A Expired CA1206559A (en) | 1983-03-04 | 1983-02-07 | Method of and apparatus for detecting change in the breakoff point of a droplet generation system |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JPS59159046A (enrdf_load_stackoverflow) |
| AU (1) | AU563027B2 (enrdf_load_stackoverflow) |
| CA (1) | CA1206559A (enrdf_load_stackoverflow) |
| CH (1) | CH654925A5 (enrdf_load_stackoverflow) |
| DE (1) | DE3307789A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2542110B1 (enrdf_load_stackoverflow) |
| GB (1) | GB2136561B (enrdf_load_stackoverflow) |
| NL (1) | NL8300783A (enrdf_load_stackoverflow) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3512090C1 (de) * | 1985-04-03 | 1986-10-02 | Eltro GmbH, Gesellschaft für Strahlungstechnik, 6900 Heidelberg | Schaltungsanordnung zur Aufbereitung von gleichzeitig zur Verarbeitung anstehenden sehr unterschiedlich grossen Signalamplituden |
| ATE298084T1 (de) | 1997-01-31 | 2005-07-15 | Horticulture & Food Res Inst | Optische vorrichtung und methode |
| US6071689A (en) | 1997-12-31 | 2000-06-06 | Xy, Inc. | System for improving yield of sexed embryos in mammals |
| US6149867A (en) | 1997-12-31 | 2000-11-21 | Xy, Inc. | Sheath fluids and collection systems for sex-specific cytometer sorting of sperm |
| US7208265B1 (en) | 1999-11-24 | 2007-04-24 | Xy, Inc. | Method of cryopreserving selected sperm cells |
| AU760689B2 (en) * | 2000-03-28 | 2003-05-22 | Matsushita Electric Works Ltd. | Particle sensor |
| AU3768902A (en) | 2000-11-29 | 2002-06-11 | Xy Inc | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| US7713687B2 (en) | 2000-11-29 | 2010-05-11 | Xy, Inc. | System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations |
| GB2388585A (en) * | 2002-05-17 | 2003-11-19 | Unilever Plc | Dosing system with multi-spout nozzle |
| EP2283724B8 (en) | 2002-08-01 | 2016-03-16 | Xy, Llc | Heterospermic insemination to assess sperm function |
| US8486618B2 (en) | 2002-08-01 | 2013-07-16 | Xy, Llc | Heterogeneous inseminate system |
| MXPA05001654A (es) | 2002-08-15 | 2005-10-18 | Xy Inc | Citometro de flujo de alta resolucion. |
| US7169548B2 (en) | 2002-09-13 | 2007-01-30 | Xy, Inc. | Sperm cell processing and preservation systems |
| US7758811B2 (en) | 2003-03-28 | 2010-07-20 | Inguran, Llc | System for analyzing particles using multiple flow cytometry units |
| NZ544103A (en) | 2003-05-15 | 2010-10-29 | Xy Llc | Efficient haploid cell sorting for flow cytometer systems |
| CA2561661C (en) | 2004-03-29 | 2015-11-24 | Monsanto Technology Llc | Sperm suspensions for sorting into x or y chromosome-bearing enriched populations |
| EP1769067A2 (en) | 2004-07-22 | 2007-04-04 | Monsanto Technology LLC | Process for enriching a population of sperm cells |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3380584A (en) * | 1965-06-04 | 1968-04-30 | Atomic Energy Commission Usa | Particle separator |
| BE793185A (fr) * | 1971-12-23 | 1973-04-16 | Atomic Energy Commission | Appareil pour analyser et trier rapidement des particules telles que des cellules biologiques |
| US3963606A (en) * | 1974-06-03 | 1976-06-15 | Coulter Electronics, Inc. | Semi-automatic adjusting delay for an electronic particle separator |
| NL180704C (nl) * | 1976-06-14 | Coulter Electronics | Inrichting voor gelijktijdige optische meting van kenmerken van zich in een suspensie bevindende deeltjes. | |
| US4047183A (en) * | 1976-11-04 | 1977-09-06 | International Business Machines Corporation | Method and apparatus for controlling the formation and shape of droplets in an ink jet stream |
| US4318480A (en) * | 1979-08-20 | 1982-03-09 | Ortho Diagnostics, Inc. | Method and apparatus for positioning the point of droplet formation in the jetting fluid of an electrostatic sorting device |
-
1983
- 1983-02-07 CA CA000421053A patent/CA1206559A/en not_active Expired
- 1983-02-08 GB GB08303440A patent/GB2136561B/en not_active Expired
- 1983-02-08 AU AU11244/83A patent/AU563027B2/en not_active Ceased
- 1983-03-02 JP JP58033000A patent/JPS59159046A/ja active Granted
- 1983-03-03 CH CH1159/83A patent/CH654925A5/fr not_active IP Right Cessation
- 1983-03-03 NL NL8300783A patent/NL8300783A/nl not_active Application Discontinuation
- 1983-03-03 FR FR8303501A patent/FR2542110B1/fr not_active Expired
- 1983-03-04 DE DE19833307789 patent/DE3307789A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NL8300783A (nl) | 1984-10-01 |
| FR2542110A1 (fr) | 1984-09-07 |
| GB8303440D0 (en) | 1983-03-16 |
| JPH0324626B2 (enrdf_load_stackoverflow) | 1991-04-03 |
| CH654925A5 (fr) | 1986-03-14 |
| GB2136561A (en) | 1984-09-19 |
| AU1124483A (en) | 1984-08-16 |
| DE3307789A1 (de) | 1984-09-06 |
| DE3307789C2 (enrdf_load_stackoverflow) | 1991-09-19 |
| AU563027B2 (en) | 1987-06-25 |
| FR2542110B1 (fr) | 1988-11-04 |
| GB2136561B (en) | 1986-06-25 |
| JPS59159046A (ja) | 1984-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |