CA1202917A - Process for producing subculturable lymphokine- producing human t cell hybridomas - Google Patents

Process for producing subculturable lymphokine- producing human t cell hybridomas

Info

Publication number
CA1202917A
CA1202917A CA000414159A CA414159A CA1202917A CA 1202917 A CA1202917 A CA 1202917A CA 000414159 A CA000414159 A CA 000414159A CA 414159 A CA414159 A CA 414159A CA 1202917 A CA1202917 A CA 1202917A
Authority
CA
Canada
Prior art keywords
cell
cells
human
hybridoma
acute leukemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000414159A
Other languages
English (en)
French (fr)
Inventor
Toshiaki Osawa
Yoshiro Kobayashi
Makoto Asada
Masahiro Higuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Denka Co Ltd
Original Assignee
Denki Kagaku Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Denki Kagaku Kogyo KK filed Critical Denki Kagaku Kogyo KK
Application granted granted Critical
Publication of CA1202917A publication Critical patent/CA1202917A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA000414159A 1981-10-28 1982-10-26 Process for producing subculturable lymphokine- producing human t cell hybridomas Expired CA1202917A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56171505A JPS6011889B2 (ja) 1981-10-28 1981-10-28 継代可能なリンホカイン産生ヒトｔ細胞融合株及びその取得方法
JP171505/81 1981-10-28

Publications (1)

Publication Number Publication Date
CA1202917A true CA1202917A (en) 1986-04-08

Family

ID=15924347

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000414159A Expired CA1202917A (en) 1981-10-28 1982-10-26 Process for producing subculturable lymphokine- producing human t cell hybridomas

Country Status (5)

Country Link
JP (1) JPS6011889B2 (de)
CA (1) CA1202917A (de)
DE (1) DE3239863C2 (de)
FR (1) FR2515208B1 (de)
GB (1) GB2108528B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1214123A (en) * 1983-01-20 1986-11-18 Masashi Matsui Cell lines for use in the preparation of hybridoma cells
JPS59169492A (ja) * 1983-03-15 1984-09-25 Asahi Chem Ind Co Ltd ヒト融合細胞からの生理活性物質の産生方法
EP0179127B1 (de) * 1984-04-13 1989-12-13 Akzo N.V. Leukoregulin, ein antitumor-lymphokin und dessen verwendung als heilmittel
US4843004A (en) * 1984-05-11 1989-06-27 Sloan-Kettering Institute For Cancer Research Method for the production of human T-T cell hybrids and production suppressor factor by human T-T cell hybrids
US4959457A (en) * 1984-05-31 1990-09-25 Genentech, Inc. Anti-lymphotoxin
US4665032A (en) * 1984-06-28 1987-05-12 Cornell Research Foundation, Inc. Human T cell hybridomas which produce immunosuppressive factors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE57107T1 (de) * 1981-01-28 1983-04-14 Coats Patons Plc, Glasgow, Scotland Verfahren zur herstellung von monoklonalen antikoerpern und zellen, faehig diese antikoerper herzustellen.

Also Published As

Publication number Publication date
FR2515208A1 (fr) 1983-04-29
GB2108528B (en) 1984-12-19
DE3239863A1 (de) 1983-05-05
DE3239863C2 (de) 1985-08-29
FR2515208B1 (fr) 1985-07-19
GB2108528A (en) 1983-05-18
JPS6011889B2 (ja) 1985-03-28
JPS5872520A (ja) 1983-04-30

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