CA1198679A - Pharmaceutical compositions for promoting healing of wounds - Google Patents

Pharmaceutical compositions for promoting healing of wounds

Info

Publication number
CA1198679A
CA1198679A CA000385170A CA385170A CA1198679A CA 1198679 A CA1198679 A CA 1198679A CA 000385170 A CA000385170 A CA 000385170A CA 385170 A CA385170 A CA 385170A CA 1198679 A CA1198679 A CA 1198679A
Authority
CA
Canada
Prior art keywords
weight
composition
amino acids
gel
semi
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000385170A
Other languages
English (en)
French (fr)
Inventor
David Cottier
Richard F. Calver
John K. Stanley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ed Geistlich Soehne AG fuer Chemische Industrie
Original Assignee
Ed Geistlich Soehne AG fuer Chemische Industrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ed Geistlich Soehne AG fuer Chemische Industrie filed Critical Ed Geistlich Soehne AG fuer Chemische Industrie
Application granted granted Critical
Publication of CA1198679A publication Critical patent/CA1198679A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/21—Acids
    • A61L2300/214—Amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000385170A 1980-09-04 1981-09-03 Pharmaceutical compositions for promoting healing of wounds Expired CA1198679A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8028554 1980-09-04
GB8028554 1980-09-04

Publications (1)

Publication Number Publication Date
CA1198679A true CA1198679A (en) 1985-12-31

Family

ID=10515840

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000385170A Expired CA1198679A (en) 1980-09-04 1981-09-03 Pharmaceutical compositions for promoting healing of wounds

Country Status (15)

Country Link
EP (1) EP0047647B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5780316A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU7486081A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE890230A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1198679A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH650148A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3173310D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK390181A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES8307491A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI812708L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2489145A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2082911B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1209894B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ198259A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA816124B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0302536B1 (en) * 1982-04-22 1992-11-19 E.R. Squibb & Sons, Inc. Granules for use in treating wounds
US4604384A (en) * 1982-06-24 1986-08-05 Smith Robert A Pharmaceutical gel composition
GR79380B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1982-09-28 1984-10-22 Johnson & Johnson Prod Inc
EP0137743A3 (en) * 1983-09-13 1986-10-01 Ed. Geistlich Söhne Ag Für Chemische Industrie Topically administrable pharmaceutical compositions
DD248961A1 (de) * 1984-05-22 1987-08-26 Akad Wissenschaften Ddr Verfahren zur herstellung wundheilungsfoerdernder praeparationen
EP0274532B1 (en) * 1986-06-13 1992-09-09 Japan Immuno Research Laboratories Co., Ltd. Wound-healing drug and cosmetics
EP0321709A3 (en) * 1987-12-23 1990-04-04 Francisco José Izundegui MacDonnell Fast healing and binding chemical compound or curative agent for healing wounded live animal and human soft tissues inflicted by cutting edges or separating forces
US4871718A (en) * 1987-12-29 1989-10-03 Raymond A. Roncari Composition of matter for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair
GB2276819B (en) * 1993-03-23 1996-12-11 Johnson & Johnson Medical Aqueous wound treatment composition comprising a polysaccharide and hexylene glycol
US5670169A (en) * 1993-12-20 1997-09-23 E.R. Squibb & Sons, Inc. Wound hydrating gel with novel preservative system and low cytotoxicity
GB2291348B (en) * 1994-07-18 1999-01-20 Johnson & Johnson Medical Sterile gel composition for wound treatment comprising alginate and polyhydric alcohol
RU2165754C2 (ru) * 1997-04-02 2001-04-27 Мчедлидзе Тамаз Шалвович Мазь для лечения гнойновоспалительных заболеваний, ожогов, воспалительных заболеваний суставов, трофических язв и длительно незаживающих ран, способ ее приготовления и способ лечения
WO1998043613A1 (fr) * 1997-04-02 1998-10-08 Tamaz Shalvovich Mchedlidze Onguents pour traiter tous les stades de lesions suppuratives, brulures et ulcers trophiques, modes de preparation et applications
RU2138250C1 (ru) * 1997-06-23 1999-09-27 ОАО "Нижегородский химико-фармацевтический завод" Способ получения мази "диоксиколь"
RU2146921C1 (ru) * 1997-11-05 2000-03-27 Рязанский областной клинический кожно-венерологический диспансер Мазевая композиция, стимулирующая регенерацию эпителия
RU2146923C1 (ru) * 1997-11-05 2000-03-27 Рязанский областной клинический кожно-венерологический диспансер Средство для лечения дерматозов
RU2145497C1 (ru) * 1998-04-16 2000-02-20 Государственный научный центр лекарственных средств Средство для лечения гнойно-некротических процессов
RU2135180C1 (ru) * 1999-02-15 1999-08-27 Фармацевтическое научно-производственное предприятие "Ретиноиды" (акционерное общество закрытого типа) Мазь для заживления ран
US7514097B1 (en) 1999-11-09 2009-04-07 Denki Kagaku Kogyo Kabushiki Kaisha Use of soluble cellulose derivative having been made hardly soluble in water and process for producing the same
WO2002094256A1 (en) * 2001-05-23 2002-11-28 Debatosh Datta Lysine and/or analogues and/or polymers thereof for promoting wound healing and angiogenesis
RU2349302C1 (ru) * 2007-09-21 2009-03-20 Виталий Георгиевич Пшеничников Фармацевтическая композиция для наружного применения "офломелид" при гнойно-воспалительных заболеваниях
US10413528B2 (en) * 2014-10-20 2019-09-17 John H. Plumb Methods to inhibit infection during wound healing with topical compositions including amino acids
WO2019035953A1 (en) 2017-08-18 2019-02-21 Calwood Nutritionals, Llc COMPOSITIONS AND METHODS FOR INCREASING MUSCLE MASS AND MUSCLE STRENGTH, TREATING SKIN, REDUCING WEAR AND DEGRADING FROM AGING AND EXPOSURE AND ENHANCING RECOVERY OF A STRESS SUCH AS EXERCISE AND TRAUMA
RU2733714C2 (ru) * 2017-11-07 2020-10-06 Общество с ограниченной ответственностью "Трейдсервис" Стабильная комбинированная фармацевтическая композиция диоксидина и анестетиков

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786076A (en) * 1966-10-13 1974-01-15 J Morelle Lipoaminoacids
FR2215212B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1973-01-18 1976-03-05 Seperic Ch
DE2438703C3 (de) * 1974-08-12 1980-02-21 Ernst Dr.Med. 4970 Bad Oeynhausen Lauven Verwendung einer Mischung bei der Rheumabehandlung

Also Published As

Publication number Publication date
JPS5780316A (en) 1982-05-19
ES505172A0 (es) 1983-07-01
GB2082911B (en) 1984-04-18
IT8149222A0 (it) 1981-09-03
IT1209894B (it) 1989-08-30
FR2489145B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-05-25
DE3173310D1 (en) 1986-02-06
NZ198259A (en) 1985-05-31
GB2082911A (en) 1982-03-17
AU7486081A (en) 1982-03-11
EP0047647B1 (en) 1985-12-27
FI812708A7 (fi) 1982-03-05
CH650148A5 (fr) 1985-07-15
DK390181A (da) 1982-03-05
BE890230A (fr) 1982-01-04
FI812708L (fi) 1982-03-05
ZA816124B (en) 1982-09-29
EP0047647A3 (en) 1982-09-15
FR2489145A1 (fr) 1982-03-05
EP0047647A2 (en) 1982-03-17
ES8307491A1 (es) 1983-07-01

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Legal Events

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