CA1184155A - Fitments for containers from which liquid is intended to be withdrawn by a hollow needle or tube - Google Patents
Fitments for containers from which liquid is intended to be withdrawn by a hollow needle or tubeInfo
- Publication number
- CA1184155A CA1184155A CA000392729A CA392729A CA1184155A CA 1184155 A CA1184155 A CA 1184155A CA 000392729 A CA000392729 A CA 000392729A CA 392729 A CA392729 A CA 392729A CA 1184155 A CA1184155 A CA 1184155A
- Authority
- CA
- Canada
- Prior art keywords
- needle
- container
- liquid
- fitment
- tube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1406—Septums, pierceable membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D51/00—Closures not otherwise provided for
- B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
Abstract
S P E C I F I C A T I O N
"Fitments for Containers from which Liquid is Intended to be Withdrawn by a Hollow Needle or Tube"
ABSTRACT OF THE DISCLOSURE
A container provided with a self-sealing closure member, through which a needle may be inserted to withdraw liquid from the container, is fitted with a sterilizing cap. The space within the upper region of the cap is divided into compartments by partitions, and each of the compartments contains a sterilizing substance.
On withdrawal of a dose of liquid from the container a needle is caused to penetrate a weakened region of the cap and to pass through one of the compartments prior to penetrating the closure member and being introduced into the liquid within the container. After the appropriate dose has been taken up the needle may be withdrawn. The needle is coated with sterilizing substance both on introduction of the needle into the container and on withdrawal of the needle, and this serves to present contamination of the liquid within the container by the needle as well as infection of the site of injection where the needle is subsequently used to perform an injection.
After the needle has been passed through one of the compartments a number of times, it may be passed through another of the compartments which contains fresh sterilizing substance.
"Fitments for Containers from which Liquid is Intended to be Withdrawn by a Hollow Needle or Tube"
ABSTRACT OF THE DISCLOSURE
A container provided with a self-sealing closure member, through which a needle may be inserted to withdraw liquid from the container, is fitted with a sterilizing cap. The space within the upper region of the cap is divided into compartments by partitions, and each of the compartments contains a sterilizing substance.
On withdrawal of a dose of liquid from the container a needle is caused to penetrate a weakened region of the cap and to pass through one of the compartments prior to penetrating the closure member and being introduced into the liquid within the container. After the appropriate dose has been taken up the needle may be withdrawn. The needle is coated with sterilizing substance both on introduction of the needle into the container and on withdrawal of the needle, and this serves to present contamination of the liquid within the container by the needle as well as infection of the site of injection where the needle is subsequently used to perform an injection.
After the needle has been passed through one of the compartments a number of times, it may be passed through another of the compartments which contains fresh sterilizing substance.
Description
4~55 This invention relates to fitments for containers from which liquid is intended to be withdrawn by a hollow needle or -tube. The liquid may be an injection liquid for use in injecting humans, animals, fruit or vegetables.
Farmers have for many years given rou-tine oral drenches of anthelminthics to suppress the e~fects of intestinal and other parasitic worms in cattle, sheep and pigs. However -these drenches only become e~fective af-ter a relatively long period. Although it has recently become possible to achieve the same effect in a much shorter space of time by injecting the animal, there has been a reluctance by ~armers to use the new method. This is because it is not usual to sterilize the site of injection either before or after injec-tion3 and the same needle is generally used for injecting a large number of animals without sterilizing the needle between each injection. In addition, where the dose is withdrawn directly from an injection liquid container by inserting the needle into the container, the unsterilized needle may con-taminate the remainder of the injectlon liquid in the container. Thus there is a significant chance of the site of injection becoming infected leading to an abscess. Also, especially with sheep, there are several r utine injections given to stop various clostridial complications and each time the animal is injected it increases the risk of rejection of the carcass for human consumption due to abscesses.
It is known in the field of human medicine to provide an injection liquid container with a self-sealing closure member through which the needle may be passed to withdraw a dose from the container. On withdrawal of the needle the closure member will self-seal and thereby prevent contamination of the injection liquid directly from the enviro~ment. However some contamination of the liquid on insertion of the needle into the container is virtually inevitable.
It is an object of -this invention to provide a fitment for an injection liquid container which serves to automatically sterilize the needle as a dose is withdrawn from the container. It is a further obJect f the invention to provide such a fitment which serves to prevent contamination of the liquid in the container by the needle.
According to the invention there is provided ~4~S5;
a fitmeIlt for ~ container ~rom which liquid is intended to be withdrawn by insertîng a hollow needle or tube into ~he container, the fitment belng provided to steri-lise the needle or tube ~s it is introduced into the container to withdraw liquid therefrom, and comprising an enclosure incorporating means ~or sterili~ing the needle or tube as it is moved therethrough lnto the con~
tainer9 the enclosure having an end wall incorporating a portion which is integrally formed with the end wall and which may be separated therefrom so as to form an aper-ture in the end wall through which the point of the needle or -tube may be passed into the enclosure.
Preferably the fitment is in -the form of a cap for fitting to a suitably shaped portion of the container through which the needle or tube is intended to be in-serted. Where the liquid is to be withdrawn by a needle, the cap may be fitted over a closure member of the con-tainer. Thus 9 if the closure member is of the conven-tional self-sealing type, the needle may pass through the closure member after passing through the cap and the closure member will automatically seal the container again on withdraw~ of the needle. The cap may be provided with an inwardly extending lip for engaging under a shoulder on the container.
The fitment may be divided into a plurality of compartments separated by one or more partitions, each compartment containing sterilising means. This enables the sterilising means in a second compartment to be used for sterilising the needle or tuhe when the sterilising means in a first compartment has become contaminated.
3a -Preferably a plurality of partitions extend radially outwardly from a common axis and are equiangularly distributed.
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\
\
~i."
The invention also pro~ides a liquid container fitted with such a fitment, the fitment preferably being fitted over a self-sealing closure member of -the container.
In order that the invention may be more fully understood, an embodiment of the invention will now be described, by way of example, with reference to -the accompanying drawing, in which:
Figure 1 is a vertical section through an injection liquid bottle fitted with a cap in accordance with the invention;
Figure 2 is a horizontal section through the cap, taken along the line II - II in Figure 1; and Figure 3 is a view of the cap from above.
The sterilizing cap 1 is shown fitted to a collapsible plas-tics bottle 2 containing injection liquid 3 and provided with a self-sealing closure member 4 of a known type. The closure member 4 comprises a rubber self sealing element 5 and a metal ring 6 which cooperates wi-th an annular flange 7 provided on the bottle 2 -to clamp the closure member 4 on to the bottle 2.
The cap 1 is made of plastics ma-terial and comprises a circular -top wall ~ and a cylindrical side wall 9 extending downwardly therefrom. The space within the upper region of the cap 1 is divided into three compartmen-ts 20, 21 and 22 by means of three equiangularly extending partitions 10, 11 and 12 as shown mos-t clearly in Figure 2.
Each of the compartments contains sterilizing means (not shown) such as a sponge impregnated with ~terilising liquid, for example. Alternatively each compartment may contain a sterilising powder or a sterilising gel.
Furthermore the cap 1 i5 attached to ~he bottl~ 2 by an inwardly extending anm~lar lip 13 at ~he bottom of the side wall 9 which lip 13 engages underneath -the ring 6 of the closure member 4. The lip 13 may be formed a~ter the cap 1 has been fitted over the closure member 4, for example by means of a heat treatment. Alternatively the lip 1~ may be preformed, and the side wall 9 of the cap 1 may be deformable to enable ~he lip 13 to fit over the closure member 4 and to snap in under the ring 6~ In addition the lip 13 m~y be provided with a ramp surface to enable it to fit over the closure member 4 more easily. A circular rubber seal 17 is provided between the bottoms ~f the partitions 10, 11 and 12 and the ~op of the closure member 4.
As shown in Figure 3~ the top wall 8 of the cap 1 is provided with three regions 14, 15 and 16 each of which is easily removable from the remainder of the top wall so as to enable a needle or tube to be passed through the aperture so formed into the sterilising means in *he associ.ated compar$ment 209 21 or 22, In order to withdraw a dose of injection liquid 3 froM the bottle 2, one of the three removable re~ions 14~ 15 and 16 is forcibly removed from the top _ 6 --wall 8 of the cap 1 and discarded, and ~he needle of an injection gun is passed through the aperture so formed in the top wall 8 and through one of the com~
par-tments 20, 21 and 22 containing a sterilising sub-stance. The ~eedle is ^then caused to penetrate theseal 17 and the self-seali~g element 5 prior to being introduced into the liquid 3 within the bottle 2.
After the appropriate dose has been taken up, the needle may be withdrawn and the bottle 2 will be auto-matically resealed by the self-sealing element 5 thus preventing contamination of the ]iquid 3 remaining within the bottle 2 from the environment~ During the process of introducing the needle into9 and withdrawing the needle from, the bottle 2, the needle is coated with sterilising substance. This coating sterilises the needle prior to injection as well as the site of in-jection due to some of the sterilising substance coating the needle being transferred to the site of injection.
Also the needle is sterilised as it is actually intro-duced into the bottle`2 and this prevents c3ntaminationof the liquid 3 by the needle.
When the compar~ment 20, 21 or 22 in the cap 1 through which the needle has passed has become con-tamined after a number of doses have been withdrawn or due to a considerable period of time having elapsed since the first dose was taken, a subsequent dose may be taken by removing a further one of the removable regions 14, 15 and 16 of the top wall 8 and passing the needle ;5 through a fur~her one of the compartments 20, 21 and 22 containing fresh sterilising substance into the liquid 3 in the bottle 2. Similarly the sterilsing substance in the third compartment 20, 21 or ~2 may be used to sterilise the needle when the other two com~
partments have become contaminated.
Whilst the form of the invention described above with reference to the drawing is intended primarily for fitting to containe~ filled with injection liquid which is to be withdrawn there~rom by a hollow needle prior to performing an iniection with the needle, it should be understood that a similar sterilising cap, but provided with only one compartment containing sterilising substance, may be fitted to a container for a liquid, such as glucose~ which is to be introduced directly into a patientls blood supply. In use, a needle at one end of a flexible tube is automatically sterilised by the cap as i-t is inserted into the con-tainer, and a further needle at the other end of the flexible tube is inserted into the patient's arm. The sterilising cap may also be used in other applications where a liquid is to be withdrawn from a container by a hollow needle.
In view of the provision of the removable portions 14, 15 and 16 the sterilising substance in each compartment 20, 21 or 22 is prevented from being con-tamina-Sed from outside until the sterilising subst~nce in the appropriate compartment is to be used for sterilising a needle. Furthermore it is a straight-forward operation to remove one of the removable portions 14~ 15 and 16 when liquid is to be withdrawn from the bottle, and the needle may then be inserted into the bottle without any danger to the user.
Whilst the word "sterilising'l is used in this specification in the sense of killing micro-organisms, such as bacteria or viruses, it should be understood ~hat it is not essential that all micro-organisms are killed, ~hat is to say that the needleor tube is rendered absolutely sterile.
,~
Farmers have for many years given rou-tine oral drenches of anthelminthics to suppress the e~fects of intestinal and other parasitic worms in cattle, sheep and pigs. However -these drenches only become e~fective af-ter a relatively long period. Although it has recently become possible to achieve the same effect in a much shorter space of time by injecting the animal, there has been a reluctance by ~armers to use the new method. This is because it is not usual to sterilize the site of injection either before or after injec-tion3 and the same needle is generally used for injecting a large number of animals without sterilizing the needle between each injection. In addition, where the dose is withdrawn directly from an injection liquid container by inserting the needle into the container, the unsterilized needle may con-taminate the remainder of the injectlon liquid in the container. Thus there is a significant chance of the site of injection becoming infected leading to an abscess. Also, especially with sheep, there are several r utine injections given to stop various clostridial complications and each time the animal is injected it increases the risk of rejection of the carcass for human consumption due to abscesses.
It is known in the field of human medicine to provide an injection liquid container with a self-sealing closure member through which the needle may be passed to withdraw a dose from the container. On withdrawal of the needle the closure member will self-seal and thereby prevent contamination of the injection liquid directly from the enviro~ment. However some contamination of the liquid on insertion of the needle into the container is virtually inevitable.
It is an object of -this invention to provide a fitment for an injection liquid container which serves to automatically sterilize the needle as a dose is withdrawn from the container. It is a further obJect f the invention to provide such a fitment which serves to prevent contamination of the liquid in the container by the needle.
According to the invention there is provided ~4~S5;
a fitmeIlt for ~ container ~rom which liquid is intended to be withdrawn by insertîng a hollow needle or tube into ~he container, the fitment belng provided to steri-lise the needle or tube ~s it is introduced into the container to withdraw liquid therefrom, and comprising an enclosure incorporating means ~or sterili~ing the needle or tube as it is moved therethrough lnto the con~
tainer9 the enclosure having an end wall incorporating a portion which is integrally formed with the end wall and which may be separated therefrom so as to form an aper-ture in the end wall through which the point of the needle or -tube may be passed into the enclosure.
Preferably the fitment is in -the form of a cap for fitting to a suitably shaped portion of the container through which the needle or tube is intended to be in-serted. Where the liquid is to be withdrawn by a needle, the cap may be fitted over a closure member of the con-tainer. Thus 9 if the closure member is of the conven-tional self-sealing type, the needle may pass through the closure member after passing through the cap and the closure member will automatically seal the container again on withdraw~ of the needle. The cap may be provided with an inwardly extending lip for engaging under a shoulder on the container.
The fitment may be divided into a plurality of compartments separated by one or more partitions, each compartment containing sterilising means. This enables the sterilising means in a second compartment to be used for sterilising the needle or tuhe when the sterilising means in a first compartment has become contaminated.
3a -Preferably a plurality of partitions extend radially outwardly from a common axis and are equiangularly distributed.
\
\
\
~i."
The invention also pro~ides a liquid container fitted with such a fitment, the fitment preferably being fitted over a self-sealing closure member of -the container.
In order that the invention may be more fully understood, an embodiment of the invention will now be described, by way of example, with reference to -the accompanying drawing, in which:
Figure 1 is a vertical section through an injection liquid bottle fitted with a cap in accordance with the invention;
Figure 2 is a horizontal section through the cap, taken along the line II - II in Figure 1; and Figure 3 is a view of the cap from above.
The sterilizing cap 1 is shown fitted to a collapsible plas-tics bottle 2 containing injection liquid 3 and provided with a self-sealing closure member 4 of a known type. The closure member 4 comprises a rubber self sealing element 5 and a metal ring 6 which cooperates wi-th an annular flange 7 provided on the bottle 2 -to clamp the closure member 4 on to the bottle 2.
The cap 1 is made of plastics ma-terial and comprises a circular -top wall ~ and a cylindrical side wall 9 extending downwardly therefrom. The space within the upper region of the cap 1 is divided into three compartmen-ts 20, 21 and 22 by means of three equiangularly extending partitions 10, 11 and 12 as shown mos-t clearly in Figure 2.
Each of the compartments contains sterilizing means (not shown) such as a sponge impregnated with ~terilising liquid, for example. Alternatively each compartment may contain a sterilising powder or a sterilising gel.
Furthermore the cap 1 i5 attached to ~he bottl~ 2 by an inwardly extending anm~lar lip 13 at ~he bottom of the side wall 9 which lip 13 engages underneath -the ring 6 of the closure member 4. The lip 13 may be formed a~ter the cap 1 has been fitted over the closure member 4, for example by means of a heat treatment. Alternatively the lip 1~ may be preformed, and the side wall 9 of the cap 1 may be deformable to enable ~he lip 13 to fit over the closure member 4 and to snap in under the ring 6~ In addition the lip 13 m~y be provided with a ramp surface to enable it to fit over the closure member 4 more easily. A circular rubber seal 17 is provided between the bottoms ~f the partitions 10, 11 and 12 and the ~op of the closure member 4.
As shown in Figure 3~ the top wall 8 of the cap 1 is provided with three regions 14, 15 and 16 each of which is easily removable from the remainder of the top wall so as to enable a needle or tube to be passed through the aperture so formed into the sterilising means in *he associ.ated compar$ment 209 21 or 22, In order to withdraw a dose of injection liquid 3 froM the bottle 2, one of the three removable re~ions 14~ 15 and 16 is forcibly removed from the top _ 6 --wall 8 of the cap 1 and discarded, and ~he needle of an injection gun is passed through the aperture so formed in the top wall 8 and through one of the com~
par-tments 20, 21 and 22 containing a sterilising sub-stance. The ~eedle is ^then caused to penetrate theseal 17 and the self-seali~g element 5 prior to being introduced into the liquid 3 within the bottle 2.
After the appropriate dose has been taken up, the needle may be withdrawn and the bottle 2 will be auto-matically resealed by the self-sealing element 5 thus preventing contamination of the ]iquid 3 remaining within the bottle 2 from the environment~ During the process of introducing the needle into9 and withdrawing the needle from, the bottle 2, the needle is coated with sterilising substance. This coating sterilises the needle prior to injection as well as the site of in-jection due to some of the sterilising substance coating the needle being transferred to the site of injection.
Also the needle is sterilised as it is actually intro-duced into the bottle`2 and this prevents c3ntaminationof the liquid 3 by the needle.
When the compar~ment 20, 21 or 22 in the cap 1 through which the needle has passed has become con-tamined after a number of doses have been withdrawn or due to a considerable period of time having elapsed since the first dose was taken, a subsequent dose may be taken by removing a further one of the removable regions 14, 15 and 16 of the top wall 8 and passing the needle ;5 through a fur~her one of the compartments 20, 21 and 22 containing fresh sterilising substance into the liquid 3 in the bottle 2. Similarly the sterilsing substance in the third compartment 20, 21 or ~2 may be used to sterilise the needle when the other two com~
partments have become contaminated.
Whilst the form of the invention described above with reference to the drawing is intended primarily for fitting to containe~ filled with injection liquid which is to be withdrawn there~rom by a hollow needle prior to performing an iniection with the needle, it should be understood that a similar sterilising cap, but provided with only one compartment containing sterilising substance, may be fitted to a container for a liquid, such as glucose~ which is to be introduced directly into a patientls blood supply. In use, a needle at one end of a flexible tube is automatically sterilised by the cap as i-t is inserted into the con-tainer, and a further needle at the other end of the flexible tube is inserted into the patient's arm. The sterilising cap may also be used in other applications where a liquid is to be withdrawn from a container by a hollow needle.
In view of the provision of the removable portions 14, 15 and 16 the sterilising substance in each compartment 20, 21 or 22 is prevented from being con-tamina-Sed from outside until the sterilising subst~nce in the appropriate compartment is to be used for sterilising a needle. Furthermore it is a straight-forward operation to remove one of the removable portions 14~ 15 and 16 when liquid is to be withdrawn from the bottle, and the needle may then be inserted into the bottle without any danger to the user.
Whilst the word "sterilising'l is used in this specification in the sense of killing micro-organisms, such as bacteria or viruses, it should be understood ~hat it is not essential that all micro-organisms are killed, ~hat is to say that the needleor tube is rendered absolutely sterile.
,~
Claims (9)
1. A fitment for a container from which liquid is intended to be withdrawn by inserting a hollow needle or tube into the container, the fitment being provided to sterilise the needle or tube as it is introduced into the container to withdraw liquid therefrom, and comprising an enclosure incorporating means for sterilising the needle or tube as it is moved therethrough into the container, the enclosure having an end wall incorporating a portion which is integrally formed with the end wall and which may be separated therefrom so as to form an aperture in the end wall through which the point of the needle or tube may be passed into the enclosure.
2. A fitment according to claim 1, wherein the fitment is in the form of a cap for fitting to a suitably shaped portion of the container through which the needle or tube is intended to be inserted.
3. A fitment according to claim 2, wherein the cap has an inwardly extending lip for engaging under a shoulder on the container.
4. A fitment according to claim 1, wherein a plurality of compartments separated by one or more partitions are disposed within the fitment, and each compartment contains sterilising means.
5. A fitment according to claim 4, wherein a plurality of partitions extend radially outwardly from a common axis and are equiangularly distributed.
6. A fitment according to claim 1, wherein the sterilising means comprises a sterilising gel or powder, or absorbent material impregnated with sterilising fluid.
7. A liquid container provided with a fitment according to claim 1.
8. A liquid container according to claim 7, wherein the container has an opening which is closed off by a closure member and the fitment is fitted over the closure member.
9. A liquid container according to claim 8, wherein the closure member is self-sealing.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8040774 | 1980-12-19 | ||
| GB8040774 | 1980-12-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1184155A true CA1184155A (en) | 1985-03-19 |
Family
ID=10518105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000392729A Expired CA1184155A (en) | 1980-12-19 | 1981-12-18 | Fitments for containers from which liquid is intended to be withdrawn by a hollow needle or tube |
Country Status (9)
| Country | Link |
|---|---|
| AU (1) | AU7865881A (en) |
| CA (1) | CA1184155A (en) |
| DE (1) | DE3149504A1 (en) |
| ES (1) | ES270939Y (en) |
| FR (1) | FR2496603A1 (en) |
| GB (1) | GB2091229B (en) |
| IT (1) | IT1169286B (en) |
| NL (1) | NL8105724A (en) |
| ZA (1) | ZA818753B (en) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8302481D0 (en) * | 1983-01-29 | 1983-03-02 | Sterimatic Holdings Ltd | Fitments for containers |
| US4645073A (en) * | 1985-04-02 | 1987-02-24 | Survival Technology, Inc. | Anti-contamination hazardous material package |
| DE4011878A1 (en) * | 1990-04-12 | 1991-10-17 | Andreas Mommer | Bottle for medicinal liquid - incorporates tear=off spout protected by outer cap |
| DE4209872C2 (en) * | 1991-05-28 | 1996-11-14 | Dade Int Inc | Device for measuring the bleeding time in vitro |
| DE29622030U1 (en) * | 1996-12-18 | 1997-02-13 | Fina Research | Termination device |
| US7243689B2 (en) | 2000-02-11 | 2007-07-17 | Medical Instill Technologies, Inc. | Device with needle penetrable and laser resealable portion and related method |
| US7331944B2 (en) | 2000-10-23 | 2008-02-19 | Medical Instill Technologies, Inc. | Ophthalmic dispenser and associated method |
| KR100865599B1 (en) | 2000-10-23 | 2008-10-27 | 피 페턴트, 인크. | Dispenser and method of filling the dispenser |
| AU2002353790A1 (en) | 2001-10-03 | 2003-04-14 | Medical Instill Technologies, Inc. | Syringe and reconstitution syringe |
| US7798185B2 (en) | 2005-08-01 | 2010-09-21 | Medical Instill Technologies, Inc. | Dispenser and method for storing and dispensing sterile food product |
| EP1517834B1 (en) | 2002-06-19 | 2012-05-23 | Medical Instill Technologies, Inc. | Sterile filling machine having needle filling station within e-beam chamber |
| JP4425140B2 (en) | 2002-09-03 | 2010-03-03 | メディカル・インスティル・テクノロジーズ・インコーポレイテッド | Liquid medicine bottle assembly |
| EP1631496B1 (en) | 2003-04-28 | 2014-02-26 | Medical Instill Technologies, Inc. | Container with valve assembly for filling and dispensing substances, and apparatus and method for filling |
| EP2631194B1 (en) * | 2012-02-22 | 2017-02-01 | Tetra Laval Holdings & Finance S.A. | A closure for a container of a pourable product |
| US20150231289A1 (en) * | 2012-08-23 | 2015-08-20 | 0736413 B.C. Ltd. | Disinfectant cap for hypodermic needles |
| US20190047756A1 (en) * | 2016-03-03 | 2019-02-14 | Engage Biotech, Inc | Disinfecting multi-dosage vial cap |
| KR102135543B1 (en) * | 2018-08-10 | 2020-07-20 | (주)지 메디 | The Injection Set |
| CN114873067B (en) * | 2022-06-17 | 2023-06-16 | 南方医科大学南方医院 | Mercury thermometer disinfection device |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2186888A (en) * | 1938-08-06 | 1940-01-09 | Burroughs Wellcome Co | Antiseptic bottle closure |
| US2459304A (en) * | 1946-08-28 | 1949-01-18 | Blank Frederick | Medical vial stopper for insuring sterile needle punctures |
| FR1532510A (en) * | 1967-05-29 | 1968-07-12 | Plug |
-
1981
- 1981-12-09 GB GB8137094A patent/GB2091229B/en not_active Expired
- 1981-12-14 DE DE19813149504 patent/DE3149504A1/en not_active Withdrawn
- 1981-12-17 FR FR8123564A patent/FR2496603A1/en active Pending
- 1981-12-18 IT IT25695/81A patent/IT1169286B/en active
- 1981-12-18 CA CA000392729A patent/CA1184155A/en not_active Expired
- 1981-12-18 NL NL8105724A patent/NL8105724A/en not_active Application Discontinuation
- 1981-12-18 ZA ZA818753A patent/ZA818753B/en unknown
- 1981-12-18 AU AU78658/81A patent/AU7865881A/en not_active Abandoned
- 1981-12-18 ES ES1981270939U patent/ES270939Y/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES270939U (en) | 1983-12-01 |
| NL8105724A (en) | 1982-07-16 |
| AU7865881A (en) | 1982-06-24 |
| GB2091229A (en) | 1982-07-28 |
| IT8125695A0 (en) | 1981-12-18 |
| GB2091229B (en) | 1984-04-26 |
| IT1169286B (en) | 1987-05-27 |
| ES270939Y (en) | 1984-06-01 |
| ZA818753B (en) | 1982-11-24 |
| FR2496603A1 (en) | 1982-06-25 |
| DE3149504A1 (en) | 1982-08-19 |
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