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US2186888A - Antiseptic bottle closure - Google Patents

Antiseptic bottle closure Download PDF

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Publication number
US2186888A
US2186888A US22339038A US2186888A US 2186888 A US2186888 A US 2186888A US 22339038 A US22339038 A US 22339038A US 2186888 A US2186888 A US 2186888A
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Grant
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Prior art keywords
bottle
air
material
closure
contents
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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Inventor
Paul E Tullar
Robert C Page
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Glaxo Wellcome Inc
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Glaxo Wellcome Inc
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S215/00Bottles and jars
    • Y10S215/03Medical

Description

Jan. 9, 1940. P. E. TULLAR fr A. 2,186,888

ANTISBPTIC BOTTLE cLosUnE Filed Aug. 6, 1938 .Pereeiea Jee. 8, 1840 UNITED STATES PATENT OFFICE 2,188,888 Amsmmc noms cLosUnE Application August 6, 1938, Serial No. 223,390

3 Claims.

This invention relates to a bottle closure and more particularly an antiseptic bottle closure to permit the withdrawal of liquid contents by means of a hypodermic needle and syringe.

In injecting various medicines into the body or veins ot a patient, it is necessary that the liquid injected be in a highly sterilized and antiseptic condition and free from contamination by dirt, dust, sporesor bacteria which are in the atmosphere under normal conditions.

An object of the invention is to maintain the sterility of the contents of a bottle during and subsequent to frequent withdrawals of said substances.

Another object 'of the invention is to provide an effective air-tight bottle closure oi' such construction that only filtered air can enter the bot-4 tle and come in contact with the contents thereof. Another object is to permit at all times an l equilibrium er altered er sterilized air with the contents 'of the bottle.

Another object is to maintain equal atmospheric pressure at all times in the bottle, thus allowing rapid withdrawal of the contents.

u Another object is to provide a closure of such construction that the bottle can be held .in any position without loss of uid or leakage of the contents into the lter thus preventing the contents from being concentrated -by evaporation.

l. Although the novel features which are believed to be characteristic of this invention will `be more particularly pointed out in the claims appended hereto, the invention itself may be better understood by referring to the following I, description taken in connection with the accompanying drawing in which speciiic embodiments thereofhave been set forth for purposes of illustration.

In the accompanying drawing,

0' Fig. 1 shows a bottle having .inserted therein an antiseptic closure embodying my invention, together with a hypodermic syringe and a hollow needle withdrawing some of the contents of the bottle;

l Fig. 2 is a top plan view partly broken away;l Fig. 3 is a sectional View of a bottle with the closure in position;

Fig. 4 is a sectional view of a modification thereof.

l0 'I'he numeral 5 denotes a bottle. The closure is made of some pliable, resilient material, preferably rubber, and is circular in form to t tightly into the neck of the bottle. It has walls 6, a bottom l and a chamber 8 containing 'some II absorbent material, preferably sterilized cotton.

The top of the chamber is covered by a ilat, thin sheet of material, preferably rubber, 9, having air vents- I0 to permit 'the ingress of air. At the bottom of the closure there is a groove II extending entirely around the closure. This l' groove II has air vents I2. To the bottom of the closure is secured, and preferably formed integral therewith, a depending ila'p or flange I3. The periphery I4 of the flange I3 isA made of extremely thin and pliable rubber or simi- 10 lar material. l

The operation of the device is as follows. Assuming the bottle 'to be completely lled with the liquid which it is desired to use, there is of course no air in the bottle. The iluid is withl5 drawn, as shown in Fig. 1, by inserting'a h ollow hypodermic needle I5 attached to the syringe I6 of usual construction. As the iluid is withdrawn, the space occupied by the amount withdrawn necessarily has to be filled up with'air. 20 The atmospheric air, by passing through the vents Ill, the sterilized absorbent material 8 and the vent holes I2 at thebottom of the closure, passes into the interior I1 of the bottle 5. When a certain amount of fluid has been withdrawn and the bottle placed in an upright or partially upright position, the incoming air will deiiect the lower part Il 'of the ange I3 away from the bottle and allow the air, which has been filtered by coming through the absorbent material, to so enter the bottle, as shown in the modied structure in Fig. 4. When the bottle is inverted or partially inverted, as shown in Fig. 1, the fluid will press the member I4 closely against the side of the' bottle and prevent the contents of the bottle from going into the absorbent material. It will thus be seen that the air in the bottle is at all times in a sterile condition.

It will be noted from Figs. 3 and 4 that the walls 6 of the structure extend upwardly, as shown in dotted lines in Fig. 4, and are then bent over the lip of the bottle I8 to form a shoulder I9. IWhile the air vent in the upper portion of the structure 6, shown at I0, is in registry with the upper part of the closure, it will be 5 understood that these vents Ill, as shown in Fig.

4, may be placed anywhere in the top of the structure for conveniencein manufacturing.

The closure is extremely simple and can be placed in the bottle by any unskilled person and can be made to lit bottles of any required size. The bottle can be held in any position Without the use of a long needle to reach the bottom thereof and all the contents of the bottle can be conveniently removed by using the needle. If

there is any alcohol or other disinfectant solution used to rinse the needle and syringe, it does not get into the contents of the bottle because the needle is thoroughly cleansed as it passes through the absorbent cotton.

We claim:

l. An antiseptic bottle closure comprising a stopper made of soft, pliable, impervious material, said stopper having a chamber lled with absorbent sterilized material,v and top and bottom walls above and below said chamber respectively adapted to be punctured by a syringe or the like to permit withdrawal of the contents of the bottle, said stopper having air vents positioned to permit passage of air into said bottle through said absorbent material as the contents of said bottle is removed and means associated with said stopper to prevent escape of liquid into said absorbent material through said air vents when the bottle is held in inverted position.

2. An antiseptic bottle closure comprising a stopper made of soft, pliable, impervious material, said stopper having a chamber filled with absorbent sterilized material, and top and bottom walls above and below said chamber respectively adapted to be punctured by a syringe or the like to permit withdrawal of the contents .through said air vents when the bottle is inverted.

3. An antiseptic bottle closure comprising a stopper made of soft, pliable, impervious material, said stopper having a chamber lled with absorbent sterilized material, and top and bottom walls above and below said chamber respectively adapted to be punctured by a syringe or the like to permit withdrawal of the contents of the bottle, a depending skirt formed on said stopper in a position to engage the inner surface of the bottle, air vents arranged in said stopper to permit passage of air through said absorbent sterilized material and around the outer surface of said skirt into the bottle, said skirt being adapted to close said air vents and prevent reverse passage of liquid into said absorbent material when the bottle is inverted.

PAUL E. TULLAR. ROBERT C. PAGE.

US2186888A 1938-08-06 1938-08-06 Antiseptic bottle closure Expired - Lifetime US2186888A (en)

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Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2571015A (en) * 1946-10-10 1951-10-09 John C Columbus Coffee maker
US2661742A (en) * 1949-08-13 1953-12-08 Hauduroy Paul Multiple container
US2754866A (en) * 1953-01-22 1956-07-17 Republic Molding Corp Flexible containers
US2830722A (en) * 1954-01-25 1958-04-15 American Thermos Products Comp Closure for vacuum-insulated containers
US2884152A (en) * 1953-08-26 1959-04-28 Merck & Co Inc Vented bottle closure
US2887108A (en) * 1953-11-18 1959-05-19 Becton Dickinson Co Syringe assembly
US3946780A (en) * 1973-01-04 1976-03-30 Sellers John C Fermentation container
US4111326A (en) * 1976-03-04 1978-09-05 Becton, Dickinson And Company Closure for air evacuated container
US4186840A (en) * 1976-03-04 1980-02-05 Becton, Dickinson And Company Cannulapierceable, self-sealing closure
US4236647A (en) * 1979-01-15 1980-12-02 Kotturan Paulson A Container for sterile liquids
US4261474A (en) * 1979-11-01 1981-04-14 Cohen Milton J Filter device for injectable fluids
US4312349A (en) * 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
FR2496603A1 (en) * 1980-12-19 1982-06-25 Seven Holdings Ltd Accessory for container designed for drawing fluid there through hollow needle or tube
US4671331A (en) * 1986-03-13 1987-06-09 Lyphomed, Inc. Cover for medicinal vial
US4700202A (en) * 1983-02-23 1987-10-13 Sharp Kabushiki Kaisha Ink cartridge in an ink jet system printer
US4769026A (en) * 1986-08-19 1988-09-06 Erbamont, Inc. Method and apparatus for purging a syringe
US4815619A (en) * 1987-07-13 1989-03-28 Turner Thomas R Medicament vial safety cap
US20090178998A1 (en) * 2007-12-31 2009-07-16 Keisha Gay Knight Closed cover for medicinal vial
US7824922B2 (en) 2001-03-09 2010-11-02 Gen-Probe Incorporated Method for removing a fluid substance from a closed system
US20130085466A1 (en) * 2009-03-30 2013-04-04 Shinagawa Co., Ltd Plug for container
WO2017151248A1 (en) * 2016-03-03 2017-09-08 Engage Biotech, Inc. Disinfecting multi-dosage vial cap
US9814650B1 (en) 2015-04-20 2017-11-14 Stephen Dailey Self-disinfecting medication vial cap assembly

Cited By (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2571015A (en) * 1946-10-10 1951-10-09 John C Columbus Coffee maker
US2661742A (en) * 1949-08-13 1953-12-08 Hauduroy Paul Multiple container
US2754866A (en) * 1953-01-22 1956-07-17 Republic Molding Corp Flexible containers
US2884152A (en) * 1953-08-26 1959-04-28 Merck & Co Inc Vented bottle closure
US2887108A (en) * 1953-11-18 1959-05-19 Becton Dickinson Co Syringe assembly
US2830722A (en) * 1954-01-25 1958-04-15 American Thermos Products Comp Closure for vacuum-insulated containers
US3946780A (en) * 1973-01-04 1976-03-30 Sellers John C Fermentation container
US4290534A (en) * 1976-03-04 1981-09-22 Becton, Dickinson And Company Cannula pierceable self-sealing closure
US4136794A (en) * 1976-03-04 1979-01-30 Becton, Dickinson And Company Cannula pierceable, self-sealing closure
US4186840A (en) * 1976-03-04 1980-02-05 Becton, Dickinson And Company Cannulapierceable, self-sealing closure
US4187952A (en) * 1976-03-04 1980-02-12 Becton, Dickinson And Company Cannula pierceable, self-sealing closure
US4226333A (en) * 1976-03-04 1980-10-07 Becton, Dickinson And Company Cannula pierceable self-sealing closure
US4111326A (en) * 1976-03-04 1978-09-05 Becton, Dickinson And Company Closure for air evacuated container
US4295572A (en) * 1976-03-04 1981-10-20 Becton, Dickinson And Company Cannula pierceable self-sealing closure
US4301936A (en) * 1976-03-04 1981-11-24 Becton, Dickinson And Company Cannula pierceable self-sealing closure
US4236647A (en) * 1979-01-15 1980-12-02 Kotturan Paulson A Container for sterile liquids
US4312349A (en) * 1979-07-23 1982-01-26 Cohen Milton J Filter device for injectable fluid
US4261474A (en) * 1979-11-01 1981-04-14 Cohen Milton J Filter device for injectable fluids
FR2496603A1 (en) * 1980-12-19 1982-06-25 Seven Holdings Ltd Accessory for container designed for drawing fluid there through hollow needle or tube
US4700202A (en) * 1983-02-23 1987-10-13 Sharp Kabushiki Kaisha Ink cartridge in an ink jet system printer
US4671331A (en) * 1986-03-13 1987-06-09 Lyphomed, Inc. Cover for medicinal vial
US4769026A (en) * 1986-08-19 1988-09-06 Erbamont, Inc. Method and apparatus for purging a syringe
US4815619A (en) * 1987-07-13 1989-03-28 Turner Thomas R Medicament vial safety cap
US8685347B2 (en) 2001-03-09 2014-04-01 Gen-Probe Incorporated Penetrable cap
USRE45194E1 (en) 2001-03-09 2014-10-14 Gen-Probe Incorporated Penetrable cap
US8052944B2 (en) 2001-03-09 2011-11-08 Gen-Probe Incorporated Penetrable cap
US8057762B2 (en) 2001-03-09 2011-11-15 Gen-Probe Incorporated Penetrable cap
US7824922B2 (en) 2001-03-09 2010-11-02 Gen-Probe Incorporated Method for removing a fluid substance from a closed system
US20090178998A1 (en) * 2007-12-31 2009-07-16 Keisha Gay Knight Closed cover for medicinal vial
US20130085466A1 (en) * 2009-03-30 2013-04-04 Shinagawa Co., Ltd Plug for container
US8888756B2 (en) * 2009-03-30 2014-11-18 Gto Ltd. Plug for container
US9814650B1 (en) 2015-04-20 2017-11-14 Stephen Dailey Self-disinfecting medication vial cap assembly
WO2017151248A1 (en) * 2016-03-03 2017-09-08 Engage Biotech, Inc. Disinfecting multi-dosage vial cap

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