CA1153376A - Antidepressant agent - Google Patents

Antidepressant agent

Info

Publication number
CA1153376A
CA1153376A CA000360824A CA360824A CA1153376A CA 1153376 A CA1153376 A CA 1153376A CA 000360824 A CA000360824 A CA 000360824A CA 360824 A CA360824 A CA 360824A CA 1153376 A CA1153376 A CA 1153376A
Authority
CA
Canada
Prior art keywords
formula
iii
pyridin
triazolo
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000360824A
Other languages
English (en)
French (fr)
Inventor
Duane F. Morrow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1153376A publication Critical patent/CA1153376A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA000360824A 1979-09-24 1980-09-23 Antidepressant agent Expired CA1153376A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/078,536 US4254124A (en) 1979-09-24 1979-09-24 Antidepressant agent
US078,536 1993-06-16

Publications (1)

Publication Number Publication Date
CA1153376A true CA1153376A (en) 1983-09-06

Family

ID=22144661

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000360824A Expired CA1153376A (en) 1979-09-24 1980-09-23 Antidepressant agent

Country Status (7)

Country Link
US (1) US4254124A (US20100223739A1-20100909-C00005.png)
EP (1) EP0025985B1 (US20100223739A1-20100909-C00005.png)
JP (1) JPS5697285A (US20100223739A1-20100909-C00005.png)
AT (1) ATE5407T1 (US20100223739A1-20100909-C00005.png)
CA (1) CA1153376A (US20100223739A1-20100909-C00005.png)
DE (1) DE3065697D1 (US20100223739A1-20100909-C00005.png)
GR (1) GR82325B (US20100223739A1-20100909-C00005.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4465683A (en) * 1979-09-14 1984-08-14 Mead Johnson & Company Anti-psychotic agents
KR100343948B1 (ko) * 1999-11-16 2002-07-24 한국과학기술연구원 피페라지닐에틸 트리아졸 화합물 및 그 제조방법
ITMI20071603A1 (it) * 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
PL3749668T3 (pl) 2018-02-07 2022-07-25 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Ciągły sposób wytwarzania trazodonu

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
FR8135M (US20100223739A1-20100909-C00005.png) * 1968-12-31 1970-08-10
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
IT1041817B (it) * 1975-08-12 1980-01-10 Acraf Prodotto farmaceutico utilizzabile nelle sindrommi cerebrali

Also Published As

Publication number Publication date
DE3065697D1 (en) 1983-12-29
US4254124A (en) 1981-03-03
JPH0224831B2 (US20100223739A1-20100909-C00005.png) 1990-05-30
EP0025985B1 (en) 1983-11-23
ATE5407T1 (de) 1983-12-15
EP0025985A1 (en) 1981-04-01
GR82325B (US20100223739A1-20100909-C00005.png) 1984-12-13
JPS5697285A (en) 1981-08-05

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Legal Events

Date Code Title Description
MKEX Expiry