CA1151641A - Cephalosporin esters and ethers - Google Patents

Cephalosporin esters and ethers

Info

Publication number
CA1151641A
CA1151641A CA000331646A CA331646A CA1151641A CA 1151641 A CA1151641 A CA 1151641A CA 000331646 A CA000331646 A CA 000331646A CA 331646 A CA331646 A CA 331646A CA 1151641 A CA1151641 A CA 1151641A
Authority
CA
Canada
Prior art keywords
formula
methyl
ester
triazin
manufactured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000331646A
Other languages
English (en)
French (fr)
Inventor
Marc Montavon
Roland Reiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1151641A publication Critical patent/CA1151641A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000331646A 1978-07-19 1979-07-12 Cephalosporin esters and ethers Expired CA1151641A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH778678 1978-07-19
CH7786/78 1978-07-19

Publications (1)

Publication Number Publication Date
CA1151641A true CA1151641A (en) 1983-08-09

Family

ID=4330453

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000331646A Expired CA1151641A (en) 1978-07-19 1979-07-12 Cephalosporin esters and ethers

Country Status (20)

Country Link
US (1) US4292428A (enExample)
EP (1) EP0008372B1 (enExample)
JP (1) JPS5515492A (enExample)
KR (1) KR830000678B1 (enExample)
AT (1) ATE2331T1 (enExample)
AU (1) AU529233B2 (enExample)
CA (1) CA1151641A (enExample)
DE (1) DE2964607D1 (enExample)
DK (1) DK295279A (enExample)
ES (1) ES8101605A1 (enExample)
FI (1) FI782683A7 (enExample)
GR (1) GR72943B (enExample)
HU (1) HU183012B (enExample)
IL (1) IL57795A (enExample)
MC (1) MC1277A1 (enExample)
NO (1) NO782998L (enExample)
NZ (1) NZ191003A (enExample)
PH (1) PH15899A (enExample)
PT (1) PT69939A (enExample)
ZA (1) ZA793501B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526977A (en) * 1981-10-07 1985-07-02 American Home Products Corporation 2-(3-Amino-5-isoxazolyl)-2-oxyimino-acetic acids
JPS61267585A (ja) * 1985-01-16 1986-11-27 Fujisawa Pharmaceut Co Ltd セフアロスポラン酸誘導体もしくはその薬理学的に許容しうる塩
US4698338A (en) * 1986-02-19 1987-10-06 Eli Lilly And Company 7[2-(2-aminothiazol-4-yl)-2-benzyloximino]acetamido-3[4-alkyl-5-oxo-6-hydroxy-3,4-dihydro-1,2,4-triazin-3-yl]thiomethyl cephalosporins

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091211A (en) * 1974-05-05 1978-05-23 Hoffmann-La Roche Inc. Cephalosporins
CA1100129A (en) * 1974-08-02 1981-04-28 William H.W. Lunn Cephalosporin compounds
GB1555471A (en) * 1975-06-19 1979-11-14 Glaxo Lab Ltd 7 carbamoylalkoxyimino acetamido 3 em 4 carboxylic acidsand derivatives thereof
AU510280B2 (en) * 1976-08-30 1980-06-19 Bristol-Myers Company Antibacterial cephalosporin agents
US4178443A (en) * 1977-06-03 1979-12-11 Hoffmann-La Roche Inc. Derivatives of 7 [-substituted oxyimins acetamido] cephalosporins
GB1599232A (en) * 1977-06-03 1981-09-30 Hoffmann La Roche 7-(2-oximinoacetamido)-cephalosporin derivatives

Also Published As

Publication number Publication date
US4292428A (en) 1981-09-29
NO782998L (no) 1980-01-22
ZA793501B (en) 1980-07-30
NZ191003A (en) 1984-05-31
AU4888079A (en) 1980-01-24
MC1277A1 (fr) 1980-05-23
IL57795A0 (en) 1979-11-30
GR72943B (enExample) 1984-01-16
ATE2331T1 (de) 1983-02-15
EP0008372A1 (de) 1980-03-05
FI782683A7 (fi) 1980-01-20
EP0008372B1 (de) 1983-01-26
PT69939A (en) 1979-08-01
ES482574A0 (es) 1980-12-16
IL57795A (en) 1982-09-30
AU529233B2 (en) 1983-06-02
KR830000678B1 (ko) 1983-03-28
PH15899A (en) 1983-04-15
JPS5515492A (en) 1980-02-02
DE2964607D1 (en) 1983-03-03
DK295279A (da) 1980-01-20
ES8101605A1 (es) 1980-12-16
HU183012B (en) 1984-04-28

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Legal Events

Date Code Title Description
MKEX Expiry