CA1142918A - Tri-py-ceph combo - Google Patents

Tri-py-ceph combo

Info

Publication number
CA1142918A
CA1142918A CA000282573A CA282573A CA1142918A CA 1142918 A CA1142918 A CA 1142918A CA 000282573 A CA000282573 A CA 000282573A CA 282573 A CA282573 A CA 282573A CA 1142918 A CA1142918 A CA 1142918A
Authority
CA
Canada
Prior art keywords
compound
hydrogen
chemical equivalent
obvious chemical
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000282573A
Other languages
English (en)
French (fr)
Inventor
Takayuki Naito
Jun Okumura
Hajime Kamachi
Seiji Iimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/771,859 external-priority patent/US4103085A/en
Priority claimed from US05/777,986 external-priority patent/US4112228A/en
Priority claimed from US05/788,056 external-priority patent/US4104469A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1142918A publication Critical patent/CA1142918A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/32Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D317/34Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CA000282573A 1976-07-13 1977-07-12 Tri-py-ceph combo Expired CA1142918A (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US70522676A 1976-07-13 1976-07-13
US05/771,859 US4103085A (en) 1977-02-24 1977-02-24 7-(Syn-α-alkoxy-iminofurylacetamido-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US771,859 1977-02-24
US05/777,986 US4112228A (en) 1976-07-13 1977-03-16 7-(D-α-Hydroxy-2-arylacetamido)-3-(2-carboxyalkyl-2,3-dihydro-s-triazolo-[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids and derivatives
US05/788,056 US4104469A (en) 1977-04-15 1977-04-15 7-(Syn-α-alkoxy-iminofuryl)acetamido-3-(2-methyl-2,3-dihydro-s-triazolo[4,3-b]pyridazin-3-on-6-ylthiomethyl)-3-cephem-4-carboxylic acids
US788,056 1977-04-15
US705,226 1985-02-25
US777,986 1996-12-24

Publications (1)

Publication Number Publication Date
CA1142918A true CA1142918A (en) 1983-03-15

Family

ID=27505490

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000282573A Expired CA1142918A (en) 1976-07-13 1977-07-12 Tri-py-ceph combo

Country Status (16)

Country Link
JP (1) JPS5328191A (el)
AU (1) AU511805B2 (el)
BE (1) BE856785A (el)
CA (1) CA1142918A (el)
CH (1) CH640239A5 (el)
DE (1) DE2731724A1 (el)
DK (1) DK143344C (el)
FI (1) FI772179A (el)
FR (1) FR2358411A1 (el)
GB (1) GB1561236A (el)
GR (1) GR81280B (el)
IE (1) IE45548B1 (el)
LU (1) LU77756A1 (el)
NL (1) NL7707820A (el)
SE (2) SE7708053L (el)
YU (1) YU171977A (el)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228061A3 (en) * 1985-12-23 1988-12-14 Takeda Chemical Industries, Ltd. Cephem compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946000A (en) * 1973-10-31 1976-03-23 Bristol-Myers Company 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids

Also Published As

Publication number Publication date
DK143344C (da) 1981-12-14
SE8205482D0 (sv) 1982-09-24
SE8205482L (sv) 1982-09-24
DE2731724A1 (de) 1978-01-19
AU511805B2 (en) 1980-09-04
CH640239A5 (en) 1983-12-30
JPS5328191A (en) 1978-03-16
DK312677A (da) 1978-01-14
FR2358411A1 (fr) 1978-02-10
LU77756A1 (el) 1978-02-08
FR2358411B1 (el) 1981-06-12
YU171977A (en) 1982-06-30
AU2698277A (en) 1979-01-18
GB1561236A (en) 1980-02-13
IE45548B1 (en) 1982-09-22
SE7708053L (sv) 1978-01-14
IE45548L (en) 1978-01-13
FI772179A (el) 1978-01-14
BE856785A (fr) 1978-01-13
GR81280B (el) 1984-12-11
NL7707820A (nl) 1978-01-17
DK143344B (da) 1981-08-10

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Legal Events

Date Code Title Description
MKEX Expiry