CA1100427A - Process for recovering protease - Google Patents

Process for recovering protease

Info

Publication number
CA1100427A
CA1100427A CA303,652A CA303652A CA1100427A CA 1100427 A CA1100427 A CA 1100427A CA 303652 A CA303652 A CA 303652A CA 1100427 A CA1100427 A CA 1100427A
Authority
CA
Canada
Prior art keywords
group
protease
organic solvent
amino acid
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA303,652A
Other languages
English (en)
French (fr)
Inventor
Yuji Nonaka
Heijiro Satoh
Kiyotaka Oyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Tosoh Corp
Original Assignee
Sagami Chemical Research Institute
Toyo Soda Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute, Toyo Soda Manufacturing Co Ltd filed Critical Sagami Chemical Research Institute
Application granted granted Critical
Publication of CA1100427A publication Critical patent/CA1100427A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/816—Enzyme separation or purification by solubility

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
CA303,652A 1977-05-23 1978-05-18 Process for recovering protease Expired CA1100427A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP58828/77 1977-05-23
JP5882877A JPS5411294A (en) 1977-05-23 1977-05-23 Recovery of protease

Publications (1)

Publication Number Publication Date
CA1100427A true CA1100427A (en) 1981-05-05

Family

ID=13095501

Family Applications (1)

Application Number Title Priority Date Filing Date
CA303,652A Expired CA1100427A (en) 1977-05-23 1978-05-18 Process for recovering protease

Country Status (4)

Country Link
US (1) US4212946A (en, 2012)
JP (1) JPS5411294A (en, 2012)
CA (1) CA1100427A (en, 2012)
DE (1) DE2822528A1 (en, 2012)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR8008024A (pt) * 1979-04-06 1981-03-31 Forenede Bryggerier As Processo para a producao enzimatica de peptideos
EP0075160B1 (en) * 1981-09-21 1987-01-07 Toyo Soda Manufacturing Co., Ltd. Process for recovering a dipeptide derivative
JPS5867655A (ja) * 1981-10-16 1983-04-22 Toyo Soda Mfg Co Ltd ジペプチドエステルとアミノ酸エステルとの付加化合物の回収法
JPS5917997A (ja) * 1982-07-23 1984-01-30 Toyo Soda Mfg Co Ltd ジペプチドエステルとアミノ酸エステルとの付加化合物の製造方法
JPS60164495A (ja) * 1984-01-16 1985-08-27 モンサント　コンパニー Ｎ‐ホルミルアミノ酸とペプチド残基の酵素的結合法
JPS6171478U (en, 2012) * 1984-10-18 1986-05-15
JPS6260376U (en, 2012) * 1985-10-04 1987-04-14
EP0344803B1 (en) * 1988-06-03 1995-09-13 Sharp Kabushiki Kaisha Electronic device with calendar function
KR930002966B1 (ko) * 1990-11-24 1993-04-16 주식회사 미 원 디펩티드의 제조방법
US5371198A (en) * 1991-12-16 1994-12-06 Novo Nordisk A/S Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
US5623059A (en) * 1992-03-09 1997-04-22 Novo Nordisk A/S Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
US5422261A (en) * 1993-04-16 1995-06-06 Baxter International Inc. Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells
US5670358A (en) * 1995-10-19 1997-09-23 Baxter International Inc. Method for inhibiting chymopapain and papain enzyme activity with polysaccharides of animal origin
JP4842058B2 (ja) * 2006-08-31 2011-12-21 三井金属アクト株式会社 車両の開閉体リフト装置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4119493A (en) * 1975-10-23 1978-10-10 (Zaidanhojin) Sagami Chemical Research Center Process for producing a peptide
US4086136A (en) * 1975-10-23 1978-04-25 (Zaidanhojin) Sagami Chemical Research Center Process for producing a peptide using a serine or thiol proteinase
DE2857828C2 (en, 2012) * 1977-01-27 1990-06-07 Toyo Soda Mfg. Co., Ltd., Shinnanyo, Yamaguchi, Jp

Also Published As

Publication number Publication date
US4212946A (en) 1980-07-15
DE2822528C2 (en, 2012) 1988-04-14
JPS5411294A (en) 1979-01-27
JPS5713268B2 (en, 2012) 1982-03-16
DE2822528A1 (de) 1978-12-07

Similar Documents

Publication Publication Date Title
CA1100427A (en) Process for recovering protease
US4436925A (en) Addition compound of dipeptide derivative and amino acid derivative
US4284721A (en) Method for manufacturing dipeptides
WO1990012805A1 (en) Postostatin and related compound thereof, or their salts
Chen et al. The preparation and reactions of mixed anhydrides of N-alkoxycarbonylamino acids
US4212945A (en) Process for recovering protease
JPS58502207A (ja) ペプチド合成およびアミノ酸封鎖剤
US5418146A (en) Process for preparing dipeptides
JPH01222795A (ja) ペプチド、特にジペプチドを酵素により造るための方法およびそのための装置
EP0149594A2 (en) Enzymatic coupling of n-formyl amino acids and/or peptide residues
US4309341A (en) Method for purifying α- L-aspartyl-L-phenylalanine lower alkyl ester
IE52242B1 (en) Preparation of amino protected-l-aspartyl-l-phenylalanine alkyl ester
CA1320923C (en) Enzyme mediated coupling reactions
FR2547816A1 (fr) Procede de synthese de l'aspartame
Stelakatos et al. Amino-acid 4-methoxybenzyl esters
US4897507A (en) Method for producing α-L-aspartyl-L-phenylalanine derivatives
CA1100948A (en) Addition compound of dipeptide derivative and amino acid derivative
Milne et al. The Use of N-Benzylsulfonyl-α-amino Acids in Enzymatic Syntheses of the L-Phenylhydrazides, and for Enzymatic Resolutions1, 2
JPH0751090A (ja) 光学活性３−アミノブタン酸の製造法及びそのエステル中間体
JPS6027519B2 (ja) ペプチド誘導体の新規合成法
Stevenson et al. SYNTHESIS OF A NONAPEPTIDE SEQUENCE (A11‐A19) OF RUBREDOXIN. Amino Acids and Peptides. XXVIII
CA1193279A (en) Method for purifying n-benzyloxycarbonyl aspartic acid
EP1224211B1 (en) Process for the preparation of a dipeptide and intermediate product in such a process
CN119504467A (zh) 一种alpha-甲基-L-亮氨酸的合成方法
EP0300450A2 (en) Method for producing alpha-L-aspartyl-L-phenylalanine methyl ester hydrochloride

Legal Events

Date Code Title Description
MKEX Expiry