CA1094561A - 1,2,3,4,10,10a-hexahydrobenz¬g|isoquinoline compounds - Google Patents

1,2,3,4,10,10a-hexahydrobenz¬g|isoquinoline compounds

Info

Publication number
CA1094561A
CA1094561A CA281,898A CA281898A CA1094561A CA 1094561 A CA1094561 A CA 1094561A CA 281898 A CA281898 A CA 281898A CA 1094561 A CA1094561 A CA 1094561A
Authority
CA
Canada
Prior art keywords
carbon atoms
formula
hydrogen
alkyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA281,898A
Other languages
English (en)
French (fr)
Inventor
Jean-Michel Bastian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH863276A external-priority patent/CH622783A5/de
Priority claimed from CH863176A external-priority patent/CH622782A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1094561A publication Critical patent/CA1094561A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/66—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having a hetero atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA281,898A 1976-07-06 1977-07-04 1,2,3,4,10,10a-hexahydrobenz¬g|isoquinoline compounds Expired CA1094561A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH8631/76 1976-07-06
CH863276A CH622783A5 (en) 1976-07-06 1976-07-06 Process for the preparation of novel hexahydrobenz[g]isoquinoline derivatives
CH863176A CH622782A5 (en) 1976-07-06 1976-07-06 Process for the preparation of novel hexahydrobenz[g]isoquinoline derivatives
CH8632/76 1976-07-06

Publications (1)

Publication Number Publication Date
CA1094561A true CA1094561A (en) 1981-01-27

Family

ID=25703556

Family Applications (1)

Application Number Title Priority Date Filing Date
CA281,898A Expired CA1094561A (en) 1976-07-06 1977-07-04 1,2,3,4,10,10a-hexahydrobenz¬g|isoquinoline compounds

Country Status (19)

Country Link
US (1) US4150136A (enExample)
JP (1) JPS537681A (enExample)
AT (1) AT366369B (enExample)
CA (1) CA1094561A (enExample)
DE (1) DE2728831A1 (enExample)
DK (1) DK285077A (enExample)
ES (2) ES460371A1 (enExample)
FI (1) FI65242C (enExample)
FR (1) FR2357547A1 (enExample)
GB (1) GB1582783A (enExample)
IE (1) IE45241B1 (enExample)
IL (1) IL52449A (enExample)
MY (1) MY8400058A (enExample)
NL (1) NL7707307A (enExample)
NZ (1) NZ184547A (enExample)
PH (1) PH14074A (enExample)
PT (1) PT66758B (enExample)
SE (2) SE7707445L (enExample)
SU (1) SU692559A3 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4678791A (en) * 1985-05-07 1987-07-07 Pennwalt Corporation 6-phenyl-1,2-3,4,4a,5-6,10b-octahydrobenz(h)isoquinolines useful for treating depression

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3325803A (en) * 1964-10-01 1967-06-13 Ibm Deflection control circuit

Also Published As

Publication number Publication date
IL52449A (en) 1981-09-13
FI771986A7 (enExample) 1978-01-07
SU692559A3 (ru) 1979-10-15
DE2728831A1 (de) 1978-01-19
PT66758A (fr) 1977-08-01
AT366369B (de) 1982-04-13
MY8400058A (en) 1984-12-31
SE7707445L (sv) 1978-01-07
NZ184547A (en) 1980-08-26
GB1582783A (en) 1981-01-14
NL7707307A (nl) 1978-01-10
IE45241B1 (en) 1982-07-14
PH14074A (en) 1981-01-26
PT66758B (fr) 1979-03-12
SE8207394L (sv) 1982-12-23
FI65242C (fi) 1984-04-10
FI65242B (fi) 1983-12-30
SE8207394D0 (sv) 1982-12-23
ATA477577A (de) 1981-08-15
ES460371A1 (es) 1979-05-01
IL52449A0 (en) 1977-10-31
FR2357547A1 (fr) 1978-02-03
JPS537681A (en) 1978-01-24
US4150136A (en) 1979-04-17
IE45241L (en) 1978-01-06
FR2357547B1 (enExample) 1980-02-15
ES476889A1 (es) 1979-07-16
AU2677177A (en) 1979-01-11
DK285077A (da) 1978-01-07

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Legal Events

Date Code Title Description
MKEX Expiry